Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 23, Pages 6728-6730Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1cc11645b
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Funding
- Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan [S0801043]
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A combination of dimethyl sulfoxide (DMSO) and trifluoroacetic anhydride (TFAA) mediates functionalization at the 2 alpha-position of indole derivatives. Carbon and heteroatom nucleophiles were directly introduced via a one-pot procedure in excellent yields.
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