A design strategy for drug-like polyheterocycles with privileged substructures for discovery of specific small-molecule modulators

Development of Fluorescent Glucose Bioprobes and Their Application on Real-Time and Quantitative Monitoring of Glucose Uptake in Living Cells

(2011) Hyang Yeon Lee et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bioactivity-Guided Navigation of Chemical Space

(2010) Robin S. Bon et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Small Molecules with High Scaffold Diversity: Exploitation of Metathesis Cascades in Combination with Inter- and Intramolecular Diels-Alder Reactions

(2010) Catherine O'Leary-Steele et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tertiary Skipped Diynes: A Pluripotent Building Block for the Modular and Diversity-Oriented Synthesis of Nitrogen Heterocycles

(2010) David Tejedor et al.   CHEMISTRY-A EUROPEAN JOURNAL

Development of a Benzopyran-Containing Androgen Receptor Antagonist to Treat Antiandrogen-Resistant Prostate Cancer

(2010) Sangmi Oh et al.   ChemMedChem

Construction of a Polyheterocyclic Benzopyran Library with Diverse Core Skeletons through Diversity-Oriented Synthesis Pathway

(2010) Sangmi Oh et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Discovery of Novel Benzopyranyl Tetracycles that Act as Inhibitors of Osteoclastogenesis Induced by Receptor Activator of NF-κB Ligand

(2010) Mingyan Zhu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antidiabetic and Antiobesity Effects of Ampkinone (6f), a Novel Small Molecule Activator of AMP-Activated Protein Kinase

(2010) Sangmi Oh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Diversity-Oriented Synthesis of Disubstituted Alkenes Using Masked Silanols

(2010) Hannah F. Sore et al.   ORGANIC LETTERS

Discovery of a novel benzopyranyl compound as a potent in vitro and in vivo osteogenic agent

(2010) Sangmi Oh et al.   MedChemComm

Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules

(2010) Warren R.J.D. Galloway et al.   Nature Communications

Principles, implementation, and application of biology-oriented synthesis (BIOS)

(2009) Wolfram Wilk et al.   BIOLOGICAL CHEMISTRY

Diversity-oriented synthesis of bicyclic and tricyclic alkaloids

(2009) Mónica Díaz-Gavilán et al.   CHEMICAL COMMUNICATIONS

Efficient Parallel Synthesis of Privileged Benzopyranylpyrazoles via Regioselective Condensation of β-Keto Aldehydes with Hydrazines

(2009) So Ok Park et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Diastereoselective Synthesis of Polycyclic Acetal-Fused Pyrano[3,2-c]pyran-5(2H)-one Derivatives

(2009) Ram Sagar et al.   JOURNAL OF ORGANIC CHEMISTRY

Gold(I)-Catalyzed Coupling Reactions for the Synthesis of Diverse Small Molecules Using the Build/Couple/Pair Strategy

(2009) Tuoping Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A small molecule that directs differentiation of human ESCs into the pancreatic lineage

(2009) Shuibing Chen et al.   Nature Chemical Biology

Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy

(2009) Takuya Uchida et al.   ORGANIC LETTERS

An Efficient One-Step Synthesis of Heterobiaryl Pyrazolo[3,4-b]pyridines via Indole Ring Opening

(2009) Sanghee Lee et al.   ORGANIC LETTERS

Synthesis of Natural-Product-Like Molecules with Over Eighty Distinct Scaffolds

(2008) Daniel Morton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diversity‐oriented synthesis

(2008) Richard J. Spandl et al.   CHEMICAL RECORD

Chemical biology—identification of small molecule modulators of cellular activity by natural product inspired synthesis

(2008) Katja Hübel et al.   CHEMICAL SOCIETY REVIEWS

Expanding the Chemical Space in Practice: Diversity-Oriented Synthesis

(2008) Marine Peuchmaur et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Diversity-Oriented Synthesis of Privileged Benzopyranyl Heterocycles froms-cis-Enones

(2008) Heeseon An et al.   JOURNAL OF ORGANIC CHEMISTRY

Facile and Efficient Synthesis of Carbohybrids as Stereodivergent Druglike Small Molecules

(2008) Ram Sagar et al.   JOURNAL OF ORGANIC CHEMISTRY

Diversity-oriented synthesis; a spectrum of approaches and results

(2008) Richard J. Spandl et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

An improved synthesis of pyrimidine- and pyrazole-based acyclo-C-nucleosides as carbohybrids

(2008) Ram Sagar et al.   TETRAHEDRON LETTERS

Towards the Optimal Screening Collection: A Synthesis Strategy

(2007) Thomas E. Nielsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION