Secretion of dengue virus envelope protein ectodomain from mammalian cells is dependent on domain II serotype and affects the immune response upon DNA vaccination

Recognition determinants of broadly neutralizing human antibodies against dengue viruses

(2015) Alexander Rouvinski et al.   NATURE

Dengue E Protein Domain III-Based DNA Immunisation Induces Strong Antibody Responses to All Four Viral Serotypes

(2015) Monica Poggianella et al.   PLoS Neglected Tropical Diseases

Climate change and dengue: a critical and systematic review of quantitative modelling approaches

(2014) Suchithra Naish et al.   BMC INFECTIOUS DISEASES

Safety and Immunogenicity of DNA Vaccines Encoding Ebolavirus and Marburgvirus Wild-Type Glycoproteins in a Phase I Clinical Trial

(2014) U. N. Sarwar et al.   JOURNAL OF INFECTIOUS DISEASES

Virus-Like Particle Secretion and Genotype-Dependent Immunogenicity of Dengue Virus Serotype 2 DNA Vaccine

(2014) J. U. Galula et al.   JOURNAL OF VIROLOGY

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

(2014) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

New Tags for Recombinant Protein Detection and O-Glycosylation Reporters

(2014) Gianluca Petris et al.   PLoS One

Characterization of the Ectodomain of the Envelope Protein of Dengue Virus Type 4: Expression, Membrane Association, Secretion and Particle Formation in the Absence of Precursor Membrane Protein

(2014) Szu-Chia Hsieh et al.   PLoS One

Induction of Neutralizing Antibody Response against Four Dengue Viruses in Mice by Intramuscular Electroporation of Tetravalent DNA Vaccines

(2014) Eakachai Prompetchara et al.   PLoS One

Chaperone fusion proteins aid entropy-driven maturation of class II viral fusion proteins

(2014) Peng Ge et al.   TRENDS IN MICROBIOLOGY

Relating structure to evolution in class II viral membrane fusion proteins

(2014) Yorgo Modis   Current Opinion in Virology

Activity of the HMGB1-derived immunostimulatory peptide Hp91 resides in the helical C-terminal portion and is enhanced by dimerization

(2013) R. Saenz et al.   MOLECULAR IMMUNOLOGY

Pichia pastoris-Expressed Dengue 2 Envelope Forms Virus-Like Particles without Pre-Membrane Protein and Induces High Titer Neutralizing Antibodies

(2013) Shailendra Mani et al.   PLoS One

Burden of dengue fever is higher than previously thought

(2013) A. Gulland   BMJ-British Medical Journal

Mutagenesis of the DI/DIII Linker in Dengue Virus Envelope Protein Impairs Viral Particle Assembly

(2012) M. de Wispelaere et al.   JOURNAL OF VIROLOGY

Structure of a Dengue Virus Envelope Protein Late-Stage Fusion Intermediate

(2012) D. E. Klein et al.   JOURNAL OF VIROLOGY

Novel AAV-based genetic vaccines encoding truncated dengue virus envelope proteins elicit humoral immune responses in mice

(2012) Xueling Li et al.   MICROBES AND INFECTION

Dengue

(2012) Cameron P. Simmons et al.   NEW ENGLAND JOURNAL OF MEDICINE

C-Terminal Helical Domains of Dengue Virus Type 4 E Protein Affect the Expression/Stability of prM Protein and Conformation of prM and E Proteins

(2012) Wen-Yang Tsai et al.   PLoS One

Antibodies targeting dengue virus envelope domain III are not required for serotype-specific protection or prevention of enhancement in vivo

(2012) Katherine L. Williams et al.   VIROLOGY

Analysis of Epitopes on Dengue Virus Envelope Protein Recognized by Monoclonal Antibodies and Polyclonal Human Sera by a High Throughput Assay

(2012) Hong-En Lin et al.   PLoS Neglected Tropical Diseases

Novel Strategies to Improve DNA Vaccine Immunogenicity

(2011) Cevayir Coban et al.   CURRENT GENE THERAPY

Protection from Secondary Dengue Virus Infection in a Mouse Model Reveals the Role of Serotype Cross-Reactive B and T Cells

(2011) S. Zompi et al.   JOURNAL OF IMMUNOLOGY

A West Nile Virus DNA Vaccine Utilizing a Modified Promoter Induces Neutralizing Antibody in Younger and Older Healthy Adults in a Phase I Clinical Trial

(2011) Julie E. Ledgerwood et al.   JOURNAL OF INFECTIOUS DISEASES

DNA Vaccines against Dengue Virus Type 2 Based on Truncate Envelope Protein or Its Domain III

(2011) Adriana S. Azevedo et al.   PLoS One

Development of dengue DNA vaccines

(2011) Janine R. Danko et al.   VACCINE

The development of recombinant subunit envelope-based vaccines to protect against dengue virus induced disease

(2011) Beth-Ann G. Coller et al.   VACCINE

Amino acid changes within the E protein hinge region that affect dengue virus type 2 infectivity and fusion

(2011) Siritorn Butrapet et al.   VIROLOGY

The Human Antibody Response to Dengue Virus Infection

(2011) Wahala M. P. B. Wahala et al.   Viruses-Basel

In Vitro Reconstitution Reveals Key Intermediate States of Trimer Formation by the Dengue Virus Membrane Fusion Protein

(2010) M. Liao et al.   JOURNAL OF VIROLOGY

Structure and Function Analysis of Therapeutic Monoclonal Antibodies against Dengue Virus Type 2

(2010) S. Sukupolvi-Petty et al.   JOURNAL OF VIROLOGY

A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation

(2010) Dorothy Beckett et al.   PROTEIN SCIENCE

Cross-Reacting Antibodies Enhance Dengue Virus Infection in Humans

(2010) W. Dejnirattisai et al.   SCIENCE

A DNA vaccine candidate encoding the structural prM/E proteins elicits a strong immune response and protects mice against dengue-4 virus infection

(2010) Danielle Malta Lima et al.   VACCINE

Evaluation of a prototype dengue-1 DNA vaccine in a Phase 1 clinical trial

(2010) Charmagne G. Beckett et al.   VACCINE

Domain-III FG loop of the dengue virus type 2 envelope protein is important for infection of mammalian cells and Aedes aegypti mosquitoes

(2010) Steven M. Erb et al.   VIROLOGY

Immature Dengue Virus: A Veiled Pathogen?

(2010) Izabela A. Rodenhuis-Zybert et al.   PLoS Pathogens

In Vitro and In Vivo Studies Identify Important Features of Dengue Virus pr-E Protein Interactions

(2010) Aihua Zheng et al.   PLoS Pathogens

Molecular evolution of dengue viruses: Contributions of phylogenetics to understanding the history and epidemiology of the preeminent arboviral disease

(2009) Scott C. Weaver et al.   INFECTION GENETICS AND EVOLUTION

Development of a novel DNA SynCon™ tetravalent dengue vaccine that elicits immune responses against four serotypes

(2009) Mathura P. Ramanathan et al.   VACCINE

Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody

(2009) W.M.P.B. Wahala et al.   VIROLOGY

A DNA vaccine candidate expressing dengue-3 virus prM and E proteins elicits neutralizing antibodies and protects mice against lethal challenge

(2008) Sérgio Oliveira De Paula et al.   ARCHIVES OF VIROLOGY

In vivo site-specific biotinylation of proteins within the secretory pathway using a single vector system

(2008) Andrea Predonzani et al.   BMC BIOTECHNOLOGY

Structural Insights into the Mechanisms of Antibody-Mediated Neutralization of Flavivirus Infection: Implications for Vaccine Development

(2008) Theodore C. Pierson et al.   Cell Host & Microbe

Characterization of Dengue Virus Complex-Specific Neutralizing Epitopes on Envelope Protein Domain III of Dengue 2 Virus

(2008) G. D. Gromowski et al.   JOURNAL OF VIROLOGY

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins

(2008) Shee-Mei Lok et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Flavivirus Precursor Membrane-Envelope Protein Complex: Structure and Maturation

(2008) L. Li et al.   SCIENCE

Characterization of dengue complex-reactive epitopes on dengue 3 virus envelope protein domain III

(2008) Kiyohiko Matsui et al.   VIROLOGY