Article
Chemistry, Multidisciplinary
Lucas P. Kreuzer, Tobias Widmann, Christina Geiger, Peixi Wang, Apostolos Vagias, Julian E. Heger, Martin Haese, Viet Hildebrand, Andre Laschewsky, Christine M. Papadakis, Peter Mueller-Buschbaum
Summary: This study investigates the water vapor-induced swelling and phase transition kinetics of thin films of a diblock copolymer. The addition of salt has different effects on the non-ionic block and the zwitterionic block, significantly increasing water incorporation and affecting the swelling temperature of the zwitterionic block.
Article
Polymer Science
Yi-hung Lin, Jung Min Kim, Bryan S. Beckingham
Summary: Produced water, a by-product of industrial operations, poses environmental issues due to the presence of various metal ions. Membrane separation processes offer a promising solution for the extraction of these substances. This study investigates the transport behavior of salts in crosslinked polymer membranes, showing that increased SBMA or MBAA content decreases the permeability of the membranes to metal ions.
Article
Chemistry, Physical
Yang Zhang, Jincheng Mao, Jinzhou Zhao, Zhengjie Liao, Tao Xu, Jinhua Mao, Hailin Sun, Lijun Zheng, Yonghao Ni
Summary: This study presents a detailed investigation on a mixture fluid composed of two different sulfobetaine-type zwitterionic Gemini surfactants, EDABS and EDAES, showing promising salt-resistance, viscoelasticity, and temperature-tolerance properties. The BES-3 fluid with a molar ratio of 1:1 exhibits the best salt-resistance due to strong interactions between the two surfactants. These results suggest strong potential for the BES-3 fluid to be used as a rheological modifier in fracturing fluid and oil-displacing agents.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biophysics
Nils Burmeister, Christel Vollstedt, Cathrin Kroeger, Timo Friedrich, Nico Scharnagl, Marcus Rohnke, Eilika Zorn, Sebastian G. Wicha, Wolfgang R. Streit, Wolfgang Maison
Summary: Zwitterionic polymer brushes were successfully grafted from bulk polyethylene via air plasma activation and radical polymerization. The resulting layers showed a low contact angle and a high density of solvent accessible zwitterions. Antifouling properties were confirmed through bacterial adhesion tests and seawater tests.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Physical
Lauren N. N. Bodkin, Zachary A. A. Krajnak, Ruiqi Dong, Chinedum O. O. Osuji, Douglas L. L. Gin
Summary: This study describes the design, synthesis, and lyotropic liquid crystal phase behavior of six cross-linkable, phosphobetaine-based, zwitterionic amphiphiles. Two of them form a Q(II) phase with aq. NH4Cl solution, creating 3D nanoporous membrane materials that can be utilized for water desalination and are resistant to ion exchange unlike traditional ionic analogues.
Article
Chemistry, Physical
Xiaoyan Liu, Joakim Stenhammar, Hakan Wennerstrom, Emma Sparr
Summary: The bending energy of the lipid membrane plays a central role in biological processes involving vesicles. By studying the response of single-component giant unilamellar vesicles (GUVs) to external osmotic stress, it is found that the osmotic pressure is balanced by the free energy of membrane bending. After equilibration, the exchange of external glucose solution for pure water leads to rapid formation of monodisperse daughter vesicles inside the GUVs through an endocytosis-like process. The results indicate that the bending energies stored in GUVs are higher than previously thought and have potential consequences for vesicle fusion/fission and osmotic regulation in living cells.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Joelle Auclair, Patrice Turcotte, Christian Gagnon, Caroline Peyrot, Kevin James Wilkinson, Francois Gagne
Summary: The toxicity of different forms of silver nanoparticles (nAg) in juvenile rainbow trout was compared in this study. It was found that dissolved Ag had the highest uptake and distribution in the fish gills, followed by spherical, cubic, and prismatic nAg. Dissolution of nAg was observed in all forms, with prismatic nAg releasing higher levels of Ag in the protein pool. Cubic nAg had a higher aggregation tendency compared to other forms. Lipid peroxidation was closely related to protein aggregation and viscosity. Biomarkers indicated changes in lipid/oxidative stress and genotoxicity, which were associated with protein aggregation loss and inflammation (NO2 levels), respectively. In general, the effects were observed in all forms of nAg, with prismatic nAg showing higher toxicity than spherical and cubic nAg. The strong relationship between genotoxicity and inflammation response suggests the involvement of the immune system in the observed responses of juvenile fish gills.
Article
Electrochemistry
Mikhail Khrizanforov, Ruslan Shekurov, Almaz Zagidullin, Tatiana Gerasimova, Kamil Ivshin, Olga Kataeva, Vasily Miluykov
Summary: The Ugi amine H-phosphinic acid was synthesized and its zwitterionic form was clearly demonstrated. Unlike other monophosphinates, it does not show double oxidation peaks, indicating a single form in solution. The oxidative potential of this compound is more positive due to its complete existence in the zwitterionic form in solution.
ELECTROCHEMISTRY COMMUNICATIONS
(2021)
Article
Engineering, Chemical
Fei Xu, Si Chen, Meng You, Jianqiang Meng
Summary: A series of novel poly (arylene ether ketone) with pendant zwitterion groups were designed and the water and salt transport properties were characterized. The study showed that the zwitterionic polymers exhibited higher water/salt permeability selectivity compared to sulfonated polymers.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Materials Science, Biomaterials
Shaifali Dhingra, Shih-Po Su, Yang-Hsiang Chan, Sampa Saha
Summary: Creating infection resistant polymer brushes with antiadhesive, bactericidal, and cell-compatible features is a promising approach to prevent biomaterial-associated infections. In this study, polysulfobetaine zwitterionic homo- and copolymer brushes were grown on a tartaric acid based aliphatic polyester substrate using surface initiated atom transfer radical polymerization. The polyZ6-co-Z12 copolymer brush composition exhibited complete bacterial growth inhibition and long-lasting antibacterial activity (>3 months), while being non-toxic to human cells.
BIOMATERIALS SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Minoru Kurisu, Reinhard Kissner, Masayuki Imai, Peter Walde
Summary: The study successfully synthesized the emeraldine salt form of polyaniline by using catalysts such as Aspergillus sp. glucose oxidase under specific conditions. The cascade reaction allowed for the production of the desired product with high aniline conversion in a shorter period of time.
Article
Multidisciplinary Sciences
Peter Nietmann, Kevin Kaub, Andrejus Suchenko, Susanne Stenz, Claas Warnecke, Mohan K. Balasubramanian, Andreas Janshoff
Summary: This study investigates the implications of different actins expressed in epithelial cells for network mechanics and dynamics. The authors find that gamma-actin forms stiffer networks compared to beta-actin, attributed to selective interactions with Mg2+-ions. They also observe that beta-actin networks show more small contraction foci, while gamma-actin networks have fewer but larger foci, indicative of a stronger interaction with myosin motors.
NATURE COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Ana Rita Narciso, Federico Iovino, Sigrun Thorsdottir, Peter Mellroth, Mario Codemo, Christian Spoerry, Francesco Righetti, Sandra Muschiol, Staffan Normark, Priyanka Nannapaneni, Birgitta Henriques-Normark
Summary: Intranasal immunization with pneumococcal membrane particles (MPs) provides excellent serotype-independent protection against invasive pneumococcal disease (IPD). The conserved lipoproteins MalX and PrsA are identified as the main antigens responsible for cross-protection. Omitting variable surface proteins and vaccine candidate PspA enhances protective immune responses to the conserved proteins.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Neurosciences
Casey N. Barber, Hana L. Goldschmidt, Qianqian Ma, Lauren R. Devine, Robert N. Cole, Richard L. Huganir, Daniel M. Raben
Summary: Lipids and their metabolic enzymes play a crucial role in regulating membrane curvature during synaptic vesicle recycling. This study identifies endogenous interactors of diacylglycerol kinase theta (DGK theta) and reveals a coordinated role between DGK theta-produced phosphatidic acid (PtdOH) and synaptotagmin-1 (Syt1) in synaptic vesicle recycling.
FRONTIERS IN SYNAPTIC NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Myriam Rahmani, Mohammed El Amine Benmalti
Summary: Theoretical calculations and molecular dynamics simulations were conducted to study the structures and vibrational frequency changes of L-alanine and its zwitterionic form in the gas phase and in solution. The results indicated significant frequency changes in solution, with water molecules preferring a specific organization around alanine's hydrophilic sites.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2022)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)