Journal
CHEMICAL COMMUNICATIONS
Volume 47, Issue 22, Pages 6248-6250Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc05396a
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Funding
- Sogang University [200810019.01]
- MEST [2010-0017543, 2010-0015392, 2010-0028226, 2010K001054]
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We present a novel approach for single DNA molecule analysis using neutravidin coated surfaces. DNA molecules are elongated and reversibly immobilized on neutravidin coated surfaces with pH and salt controls. We demonstrate restriction enzyme reactions for optical mapping and ligation for tethered DNA molecules.
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