In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines

The Final Steps of Bacillaene Biosynthesis in Bacillus amyloliquefaciens FZB42: Direct Evidence for β,γ Dehydration by a trans-Acyltransferase Polyketide Synthase

(2010) Jana Moldenhauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unnatural Polyketide Analogues Selectively Target the HER Signaling Pathway in Human Breast Cancer Cells

(2010) Seok Joon Kwon et al.   CHEMBIOCHEM

Synthetic Chain Terminators Off-Load Intermediates from a Type I Polyketide Synthase

(2010) Manuela Tosin et al.   CHEMBIOCHEM

In vitro reconstruction of tetronate RK-682 biosynthesis

(2010) Yuhui Sun et al.   Nature Chemical Biology

Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes

(2010) G. P. Horsman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functionally Distinct Modules Operate Two Consecutive α,β→β,γ Double-Bond Shifts in the Rhizoxin Polyketide Assembly Line

(2009) Björn Kusebauch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Malonyl carba(dethia)- and Malonyl oxa(dethia)-coenzyme A as Tools for Trapping Polyketide Intermediates

(2009) Manuela Tosin et al.   CHEMBIOCHEM

Multi-enzymatic synthesis

(2009) Fernando Lopez-Gallego et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The Biochemical Basis for Stereochemical Control in Polyketide Biosynthesis

(2009) Chiara R. Valenzano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Biochemical Analysis of Complex Chain-Elongation Intermediates for Interrogation of Molecular Specificity in the Erythromycin and Pikromycin Polyketide Synthases

(2009) Jonathan D. Mortison et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New natural product biosynthetic chemistry discovered by genome mining

(2009) Christophe Corre et al.   NATURAL PRODUCT REPORTS

A proteomics approach to discovering natural products and their biosynthetic pathways

(2009) Stefanie B Bumpus et al.   NATURE BIOTECHNOLOGY

Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase

(2009) S. M. Ma et al.   SCIENCE

A Polylinker Approach to Reductive Loop Swaps in Modular Polyketide Synthases

(2008) Laurenz Kellenberger et al.   CHEMBIOCHEM

Deconstruction of Iterative Multidomain Polyketide Synthase Function

(2008) J. M. Crawford et al.   SCIENCE

Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products

(2007) Jonathan Kennedy   NATURAL PRODUCT REPORTS