H5N1 influenza A virus with K193E and G225E double mutations in haemagglutinin is attenuated and immunogenic in mice

A Vero-cell-adapted vaccine donor strain of influenza A virus generated by serial passages

(2015) Weibin Hu et al.   VACCINE

Enabling the 'host jump': structural determinants of receptor-binding specificity in influenza A viruses

(2014) Yi Shi et al.   NATURE REVIEWS MICROBIOLOGY

Structural analysis of the novel influenza A (H7N9) viral Neuraminidase interactions with current approved neuraminidase inhibitors Oseltamivir, Zanamivir, and Peramivir in the presence of mutation R289K

(2013) Chinh Tran-To Su et al.   BMC BIOINFORMATICS

Structural Determinants for Naturally Evolving H5N1 Hemagglutinin to Switch Its Receptor Specificity

(2013) Kannan Tharakaraman et al.   CELL

Molecular Basis of the Receptor Binding Specificity Switch of the Hemagglutinins from both the 1918 and 2009 Pandemic Influenza A Viruses by a D225G Substitution

(2013) W. Zhang et al.   JOURNAL OF VIROLOGY

Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution

(2013) B. F. Koel et al.   SCIENCE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host

(2012) C. A. Russell et al.   SCIENCE

The 2009 pandemic H1N1 virus induces anti-neuraminidase (NA) antibodies that cross-react with the NA of H5N1 viruses in ferrets

(2012) Zhongying Chen et al.   VACCINE

The role of receptor binding specificity in interspecies transmission of influenza viruses

(2012) Masaki Imai et al.   Current Opinion in Virology

D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice

(2011) Bojian Zheng et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

PB1-mediated virulence attenuation of H5N1 influenza virus in mice is associated with PB2

(2011) J. Li et al.   JOURNAL OF GENERAL VIROLOGY

Structural Characterization of the Hemagglutinin Receptor Specificity from the 2009 H1N1 Influenza Pandemic

(2011) R. Xu et al.   JOURNAL OF VIROLOGY

Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses

(2011) Taronna R. Maines et al.   VIROLOGY

Acquisition of Human-Type Receptor Binding Specificity by New H5N1 Influenza Virus Sublineages during Their Emergence in Birds in Egypt

(2011) Yohei Watanabe et al.   PLoS Pathogens

Glycosylation at 158N of the Hemagglutinin Protein and Receptor Binding Specificity Synergistically Affect the Antigenicity and Immunogenicity of a Live Attenuated H5N1 A/Vietnam/1203/2004 Vaccine Virus in Ferrets

(2010) W. Wang et al.   JOURNAL OF VIROLOGY

Gastrointestinal Delivery of Baculovirus Displaying Influenza Virus Hemagglutinin Protects Mice against Heterologous H5N1 Infection

(2010) M. Prabakaran et al.   JOURNAL OF VIROLOGY

Receptor Specificity and Transmission of H2N2 Subtype Viruses Isolated from the Pandemic of 1957

(2010) Claudia Pappas et al.   PLoS One

Nonreplicating Vaccinia Virus Vectors Expressing the H5 Influenza Virus Hemagglutinin Produced in Modified Vero Cells Induce Robust Protection

(2009) J. Mayrhofer et al.   JOURNAL OF VIROLOGY

Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

(2009) R. J. Garten et al.   SCIENCE

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

(2008) J. Steel et al.   JOURNAL OF VIROLOGY

Growth Determinants for H5N1 Influenza Vaccine Seed Viruses in MDCK Cells

(2008) S. Murakami et al.   JOURNAL OF VIROLOGY