4.7 Article

A nucleic acid-directed, red light-induced chemical reaction

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 31, Pages 5659-5661

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0cc00744g

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Funding

  1. German Research Council (DFG) [MO 1418/1-2, 1-3]
  2. National Institute of General Medical Sciences [GM-054996]
  3. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM054996] Funding Source: NIH RePORTER

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The first nucleic acid-directed catalytic photochemical reaction that is induced by nontoxic red light was developed. This reaction is fast, high yielding, sequence specific, and enables one to functionalize an oligonucleotide.

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