4.7 Article

Label-free and naked eye detection of PNA/DNA hybridization using enhancement of gold nanoparticles

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 19, Pages 3315-3317

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b926940a

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Funding

  1. Ministry of Knowledge Economy
  2. (KRIBB, Korea), Republic of Korea

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Utilizing a gold enhancement process after inducing electrostatic interaction between positively charged gold nanoparticles and negatively charged target DNA hybridized to neutral PNA capture probes, a new method for label-free detection of DNA was developed and successfully applied to detect H5-type DNA.

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