4.7 Article

Total synthesis of (+/-)-aspercyclide A and its C19 methyl ether

Journal

CHEMICAL COMMUNICATIONS
Volume 46, Issue 11, Pages 1824-1826

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b923528k

Keywords

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Funding

  1. Medical Research Council [G0601043, G0501494, G0601116] Funding Source: Medline
  2. EPSRC [EP/E011217/1] Funding Source: UKRI
  3. MRC [G0601043, G0601116, G0501494] Funding Source: UKRI
  4. Engineering and Physical Sciences Research Council [EP/E011217/1] Funding Source: researchfish
  5. National Institute for Health Research [NF-SI-0508-10212] Funding Source: researchfish
  6. Asthma UK [08/039] Funding Source: researchfish

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The total syntheses of (+/-)-aspercyclide A (1) and its C19 methyl ether (15a) featuring Heck-Mizoroki macrocyclisation to form the 11-membered (E)-styrenyl biaryl ether lactone core are described.

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