4.7 Article

Oxidative degradation of oligo(ethylene glycol)-terminated monolayers

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 34, Pages 5112-5114

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b911155g

Keywords

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Funding

  1. NSF CAREER [CTS-0349228, DMR-0706627]
  2. NIH Nanobiology Training Program [5R90 DK71504-3]
  3. NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R90DK071504] Funding Source: NIH RePORTER

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The observation that oligo(ethylene glycol) (OEG)-terminated monolayers remained highly protein-resistant for a month at 37 degrees C in PBS buffer while they degraded faster in air can be rationalized by a proposed mechanism formulated from a model study using the first internal hydroperoxide of OEG.

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