Design, Synthesis and Biological Evaluation of Two Opioid Agonist and Cav2.2 Blocker Multitarget Ligands

Hybrid peptides endomorphin-2/DAMGO: Design, synthesis and biological evaluation

(2013) Adriano Mollica et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Biological Active Analogues of the Opioid Peptide Biphalin: Mixed α/β3-Peptides

(2013) Adriano Mollica et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery and evaluation of selective N-type calcium channel blockers: 6-Unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives

(2012) Takashi Yamamoto et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Recent Updates of N-Type Calcium Channel Blockers with Therapeutic Potential for Neuropathic Pain and Stroke

(2012) Takashi Yamamoto et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker

(2012) Adriano Mollica et al.   JOURNAL OF PEPTIDE SCIENCE

Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain

(2011) Katherine E. Hanlon et al.   BRAIN RESEARCH

Design of Novel Neurokinin 1 Receptor Antagonists Based on Conformationally Constrained Aromatic Amino Acids and Discovery of a Potent Chimeric Opioid Agonist-Neurokinin 1 Receptor Antagonist

(2011) Steven Ballet et al.   JOURNAL OF MEDICINAL CHEMISTRY

Intrathecal combination of ziconotide and morphine for refractory cancer pain: A rapidly acting and effective choice

(2011) Ilaria Alicino et al.   PAIN

Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance

(2010) TM Largent-Milnes et al.   BRITISH JOURNAL OF PHARMACOLOGY

Low molecular weight non-peptide mimics of ω-conotoxin GVIA

(2009) Peter J. Duggan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Designing Multiple Ligands – Medicinal Chemistry Strategies and Challenges

(2009) Richard Morphy et al.   CURRENT PHARMACEUTICAL DESIGN

Ziconotide: an update and review

(2008) Jason A Williams et al.   EXPERT OPINION ON PHARMACOTHERAPY

Structure–activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors

(2008) Richard S. Agnes et al.   PEPTIDES

75 years of opioid research: the exciting but vain quest for the Holy Grail

(2006) Alistair D Corbett et al.   BRITISH JOURNAL OF PHARMACOLOGY