Journal
CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 56, Issue 4, Pages 607-609Publisher
PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.56.607
Keywords
deoxyvasicinone; mackinazolinone; luotonin A; tryptanthrin; rutaecarpine; anthranilic acid
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One-pot synthesis of various 2,3-polymethylene-4(3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl2 is described, which can be applicable to the synthesis of simple 4(3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine.
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