Active Site Plasticity of a Computationally Designed Retro-Aldolase Enzyme

Computational Enzyme Design

(2013) Gert Kiss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design of Protein Catalysts

(2013) Donald Hilvert   Annual Review of Biochemistry

Evolution of a designed retro-aldolase leads to complete active site remodeling

(2013) Lars Giger et al.   Nature Chemical Biology

Iterative approach to computational enzyme design

(2012) H. K. Privett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparison of designed and randomly generated catalysts for simple chemical reactions

(2012) Yakov Kipnis et al.   PROTEIN SCIENCE

Robust design and optimization of retroaldol enzymes

(2012) Eric A. Althoff et al.   PROTEIN SCIENCE

Harnessing Protein Symmetry for Enzyme Design

(2012) Bigna Wörsdörfer et al.   ACS Catalysis

Structural Analyses of Covalent Enzyme–Substrate Analog Complexes Reveal Strengths and Limitations of De Novo Enzyme Design

(2011) Ling Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Origins of catalysis by computationally designed retroaldolase enzymes

(2010) J. K. Lassila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An exciting but challenging road ahead for computational enzyme design

(2010) David Baker   PROTEIN SCIENCE

Direct Observation of an Enamine Intermediate in Amine Catalysis

(2009) Xueyong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalysis of asymmetric aldol reaction. Catalysts and reagents

(2009) Sergei G Zlotin et al.   RUSSIAN CHEMICAL REVIEWS

A Rationally Designed Aldolase Foldamer

(2008) Manuel M. Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE