Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells

Site-Specific Labeling of Affimers for DNA-PAINT Microscopy

(2018) Thomas Schlichthaerle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ELISA method to detect α-synuclein oligomers in cell and animal models

(2018) Louise Berkhoudt Lassen et al.   PLoS One

Cytosolic proteostasis through importing of misfolded proteins into mitochondria

(2017) Linhao Ruan et al.   NATURE

Multiplexed 3D super-resolution imaging of whole cells using spinning disk confocal microscopy and DNA-PAINT

(2017) Florian Schueder et al.   Nature Communications

Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids

(2016) Mathew H. Horrocks et al.   ACS Chemical Neuroscience

Nanoscopic insights into seeding mechanisms and toxicity of α-synuclein species in neurons

(2016) Dorothea Pinotsi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation

(2016) Patrick Flagmeier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading

(2016) Marija Iljina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aβ42 assembles into specific β-barrel pore-forming oligomers in membrane-mimicking environments

(2016) Montserrat Serra-Batiste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct Observation of α-Synuclein Amyloid Aggregates in Endocytic Vesicles of Neuroblastoma Cells

(2016) Mihaela M. Apetri et al.   PLoS One

Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α-Synuclein Oligomers

(2015) Mathew H. Horrocks et al.   ANALYTICAL CHEMISTRY

Interactions between misfolded protein oligomers and membranes: A central topic in neurodegenerative diseases?

(2015) Maria Andreasen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Post-translational modification of α-synuclein in Parkinson׳s disease

(2015) Paul J. Barrett et al.   BRAIN RESEARCH

pFTAA - a high affinity oligothiophene probe that detects filamentous tau in vivo and in cultured neurons

(2015) AvivaM Tolkovsky et al.   Neural Regeneration Research

Thioflavin T as a fluorescence probe for monitoring RNA metabolism at molecular and cellular levels

(2015) Shinya Sugimoto et al.   NUCLEIC ACIDS RESEARCH

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

(2015) Sarah L. Shammas et al.   Nature Communications

Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants

(2015) Laura Tosatto et al.   Scientific Reports

The fluorescent pentameric oligothiophene pFTAA identifies filamentous tau in live neurons cultured from adult P301S tau mice

(2015) Jack Brelstaff et al.   Frontiers in Neuroscience

Direct Observations of Amyloid β Self-Assembly in Live Cells Provide Insights into Differences in the Kinetics of Aβ(1–40) and Aβ(1–42) Aggregation

(2014) Elin K. Esbjörner et al.   CHEMISTRY & BIOLOGY

The changing point-spread function: single-molecule-based super-resolution imaging

(2014) Mathew H. Horrocks et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

(2014) Ralf Jungmann et al.   NATURE METHODS

Alpha-Synuclein Function and Dysfunction on Cellular Membranes

(2014) David Snead et al.   Experimental Neurobiology

G51D α-synuclein mutation causes a novel Parkinsonian-pyramidal syndrome

(2013) Suzanne Lesage et al.   ANNALS OF NEUROLOGY

Selection of DNA Aptamers That Recognize α-Synuclein Oligomers Using a Competitive Screening Method

(2012) Kaori Tsukakoshi et al.   ANALYTICAL CHEMISTRY

Imaging Nanometer-Sized α-Synuclein Aggregates by Superresolution Fluorescence Localization Microscopy

(2012) M. Julia Roberti et al.   BIOPHYSICAL JOURNAL

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species

(2012) Steffen J. Sahl et al.   Scientific Reports

Transmission electron microscopy characterization of fluorescently labelled amyloid β 1-40 and α-synuclein aggregates

(2011) Valerie L Anderson et al.   BMC BIOTECHNOLOGY

In Situ Measurements of the Formation and Morphology of Intracellular β-Amyloid Fibrils by Super-Resolution Fluorescence Imaging

(2011) Gabriele S. Kaminski Schierle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Molecule Kinetics and Super-Resolution Microscopy by Fluorescence Imaging of Transient Binding on DNA Origami

(2010) Ralf Jungmann et al.   NANO LETTERS

Detection of elevated levels of  -synuclein oligomers in CSF from patients with Parkinson disease

(2010) T. Tokuda et al.   NEUROLOGY

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA