Identification and Characterization of a Small-Molecule Inhibitor of Death-Associated Protein Kinase 1

A PEF/Y Substrate Recognition and Signature Motif Plays a Critical Role in DAPK-Related Kinase Activity

(2014) Koen Temmerman et al.   CHEMISTRY & BIOLOGY

DAPK1-p53 Interaction Converges Necrotic and Apoptotic Pathways of Ischemic Neuronal Death

(2014) L. Pei et al.   JOURNAL OF NEUROSCIENCE

Intervention of Death-Associated Protein Kinase 1–p53 Interaction Exerts the Therapeutic Effects Against Stroke

(2014) Xiaoxi Wang et al.   STROKE

Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor

(2013) David A. Carlson et al.   ACS Chemical Biology

Structural and functional diversity in the activity and regulation of DAPK-related protein kinases

(2013) Koen Temmerman et al.   FEBS Journal

Substrate-selective and Calcium-independent Activation of CaMKII by α-Actinin

(2012) Nidhi Jalan-Sakrikar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior

(2012) Tomás J Ryan et al.   NATURE NEUROSCIENCE

The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults

(2012) Marc-André Martel et al.   NEURON

A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

(2011) Luke H. Chao et al.   CELL

Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors

(2011) Li Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

(2010) Weihong Tu et al.   CELL

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

(2010) Cory M. Johannessen et al.   NATURE

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

(2010) Peter Rellos et al.   PLOS BIOLOGY

Identification of Death-Associated Protein Kinases Inhibitors Using Structure-Based Virtual Screening

(2009) Masako Okamoto et al.   JOURNAL OF MEDICINAL CHEMISTRY