Grassypeptolides as Natural Inhibitors of Dipeptidyl Peptidase 8 and T-Cell Activation

Total Synthesis and Biological Evaluation of Grassypeptolide A

(2013) Hui Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identifying Natural Substrates for Dipeptidyl Peptidases 8 and 9 Using Terminal Amine Isotopic Labeling of Substrates (TAILS) Revealsin VivoRoles in Cellular Homeostasis and Energy Metabolism

(2013) Claire H. Wilson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Potent Elastase Inhibitors from Cyanobacteria: Structural Basis and Mechanisms Mediating Cytoprotective and Anti-Inflammatory Effects in Bronchial Epithelial Cells

(2013) Lilibeth A. Salvador et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cyanobacterial Peptides as a Prototype for the Design of Potent β-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases

(2012) Yanxia Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9

(2011) Hung-Kuan Tang et al.   FEBS LETTERS

Structure–Activity Relationship Studies on Isoindoline Inhibitors of Dipeptidyl Peptidases 8 and 9 (DPP8, DPP9): Is DPP8-Selectivity an Attainable Goal?

(2011) Sebastiaan Van Goethem et al.   JOURNAL OF MEDICINAL CHEMISTRY

Grassypeptolides F and G, Cyanobacterial Peptides fromLyngbya majuscula

(2011) Wendy L. Popplewell et al.   JOURNAL OF NATURAL PRODUCTS

Cyclic Depsipeptides, Grassypeptolides D and E and Ibu-epidemethoxylyngbyastatin 3, from a Red SeaLeptolyngbyaCyanobacterium

(2011) Christopher C. Thornburg et al.   JOURNAL OF NATURAL PRODUCTS

A Novel Role of Dipeptidyl Peptidase 9 in Epidermal Growth Factor Signaling

(2011) T.-W. Yao et al.   MOLECULAR CANCER RESEARCH

Azole-Based Cyclic Peptides from the Sea Squirt Lissoclinum Patella: Old Scaffolds, New Avenues

(2010) Wael E. Houssen et al.   CHEMBIOCHEM

Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review

(2010) C. F. Deacon   DIABETES OBESITY & METABOLISM

Grassypeptolides A−C, Cytotoxic Bis-thiazoline Containing Marine Cyclodepsipeptides

(2010) Jason C. Kwan et al.   JOURNAL OF ORGANIC CHEMISTRY

The Cytoplasmic Peptidase DPP9 Is Rate-limiting for Degradation of Proline-containing Peptides

(2009) Ruth Geiss-Friedlander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The In Vivo Expression of Dipeptidyl Peptidases 8 and 9

(2009) Denise M.T. Yu et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Grassystatins A−C from Marine Cyanobacteria, Potent Cathepsin E Inhibitors That Reduce Antigen Presentation

(2009) Jason C. Kwan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lyngbyastatins 8–10, Elastase Inhibitors with Cyclic Depsipeptide Scaffolds Isolated from the Marine Cyanobacterium Lyngbya semiplena

(2009) Jason Kwan et al.   Marine Drugs

Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: Isoindoline containing inhibitors

(2008) Sebastiaan Van Goethem et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Proteases: Multifunctional Enzymes in Life and Disease

(2008) Carlos López-Otín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total Structure Determination of Grassypeptolide, a New Marine Cyanobacterial Cytotoxin

(2008) Jason C. Kwan et al.   ORGANIC LETTERS