Selective Fluorescence Detection of Small-Molecule-Binding Proteins by Using a Dual Photoaffinity Labeling System

Triple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities

(2012) Lianne I. Willems et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery and Target Identification of an Antiproliferative Agent in Live Cells Using Fluorescence Difference in Two-Dimensional Gel Electrophoresis

(2012) Jongmin Park et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Biology of Natural Products on the Basis of Identification of Target Proteins

(2012) Minoru Ueda   CHEMISTRY LETTERS

Active/Inactive Dual-Probe System for Selective Photoaffinity Labeling of Small Molecule-Binding Proteins

(2012) Kaori Sakurai et al.   Chemistry-An Asian Journal

Cell-Based Proteome Profiling of Potential Dasatinib Targets by Use of Affinity-Based Probes

(2012) Haibin Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fully Functionalized Small-Molecule Probes for Integrated Phenotypic Screening and Target Identification

(2012) Justin S. Cisar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling

(2011) Lianne I. Willems et al.   ACCOUNTS OF CHEMICAL RESEARCH

Phosphatidylinositol 3,4,5-Trisphosphate Activity Probes for the Labeling and Proteomic Characterization of Protein Binding Partners

(2011) Meng M. Rowland et al.   BIOCHEMISTRY

Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: A comparative study

(2011) Wouter A. van der Linden et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cassia obtusifolia MetE as a Cytosolic Target for Potassium Isolespedezate, a Leaf-Opening Factor of Cassia plants: Target Exploration by a Compact Molecular-Probe Strategy

(2011) Minoru Ueda et al.   Chemistry-An Asian Journal

A Bioorthogonal Quadricyclane Ligation

(2011) Ellen M. Sletten et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Examining the Mechanism of Action of a Kinesin Inhibitor Using Stable Isotope Labeled Inhibitors for Cross-Linking (SILIC)

(2011) Sarah A. Wacker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unraveling the Protein Targets of Vancomycin in Living S. aureus and E. faecalis Cells

(2011) Jürgen Eirich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bringing chemistry to life

(2011) Michael Boyce et al.   NATURE METHODS

Click-enabled heterotrifunctional template for sequential bioconjugations

(2011) David M. Beal et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Natural Products and Their Biological Targets: Proteomic and Metabolomic Labeling Strategies

(2010) Thomas Böttcher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of HSP60 as a Primary Target ofo-Carboranylphenoxyacetanilide, an HIF-1α Inhibitor

(2010) Hyun Seung Ban et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid Cu-Free Click Chemistry with Readily Synthesized Biarylazacyclooctynones

(2010) John C. Jewett et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor

(2010) Kalinka Koteva et al.   Nature Chemical Biology

Tandem fluorescence imaging of dynamic S-acylation and protein turnover

(2010) M. M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Click Chemistry and Bioorthogonal Reactions: Unprecedented Selectivity in the Labeling of Biological Molecules

(2009) Michael D. Best   BIOCHEMISTRY

Photoaffinity Labeling Reveals Nuclear Proteins That Uniquely Recognize Cisplatin−DNA Interstrand Cross-Links

(2009) Guangyu Zhu et al.   BIOCHEMISTRY

Target profiling of small molecules by chemical proteomics

(2009) Uwe Rix et al.   Nature Chemical Biology

Enantiodifferential Approach for the Detection of the Target Membrane Protein of the Jasmonate Glycoside that Controls the Leaf Movement ofAlbizzia saman

(2008) Yoko Nakamura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binding is not enough: Flexibility is needed for photocrosslinking of Lck kinase by benzophenone photoligands

(2008) Akira Kawamura et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic Anhydrase as a Model for Biophysical and Physical-Organic Studies of Proteins and Protein−Ligand Binding

(2008) Vijay M. Krishnamurthy et al.   CHEMICAL REVIEWS

Optimization of Activity-Based Probes for Proteomic Profiling of Histone Deacetylase Complexes

(2008) Cleo M. Salisbury et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photocrosslinkers illuminate interactions in living cells

(2008) Yoshihito Tanaka et al.   Molecular BioSystems

Substrate-targeting γ-secretase modulators

(2008) Thomas L. Kukar et al.   NATURE