Alanine Scan of the Peptide Antibiotic Feglymycin: Assessment of Amino Acid Side Chains Contributing to Antimicrobial Activity

Feglymycin, a unique natural bacterial antibiotic peptide, inhibits HIV entry by targeting the viral envelope protein gp120

(2012) Geoffrey Férir et al.   VIROLOGY

Feglymycin is an Inhibitor of the Enzymes MurA and MurC of the Peptidoglycan Biosynthesis Pathway

(2011) Saskia Rausch et al.   CHEMBIOCHEM

Synthesis and Characterization of the Arylomycin Lipoglycopeptide Antibiotics and the Crystallographic Analysis of Their Complex with Signal Peptidase

(2011) Jian Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Broad-Spectrum Antibiotic Activity of the Arylomycin Natural Products Is Masked by Natural Target Mutations

(2010) Peter A. Smith et al.   CHEMISTRY & BIOLOGY

Solution Structure of Polytheonamide B, a Highly Cytotoxic Nonribosomal Polypeptide from Marine Sponge

(2010) Toshiyuki Hamada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of the Antiviral Peptide Antibiotic Feglymycin

(2009) Frank Dettner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in the Chemistry and Biology of Naturally Occurring Antibiotics

(2009) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional and biochemical analysis of a key series of ramoplanin analogues

(2009) Xiao Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway

(2009) Tanja Schneider et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

How Nature Morphs Peptide Scaffolds into Antibiotics

(2008) Elizabeth M. Nolan et al.   CHEMBIOCHEM

Design and Synthesis of Novel N-Benzylidenesulfonohydrazide Inhibitors of MurC and MurD as Potential Antibacterial Agents

(2008) Rok Frlan et al.   MOLECULES

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols