Chemical-Biological Exploration of the Limits of the Ras De- and Repalmitoylating Machinery

Development of Highly Potent Inhibitors of the Ras-Targeting Human Acyl Protein Thioesterases Based on Substrate Similarity Design

(2011) Christian Hedberg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

(2011) Marion Rusch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibiting the palmitoylation/depalmitoylation cycle selectively reduces the growth of hematopoietic cells expressing oncogenic Nras

(2011) J. Xu et al.   BLOOD

Crystal structure of the predicted phospholipase LYPLAL1 reveals unexpected functional plasticity despite close relationship to acyl protein thioesterases

(2011) Marco Bürger et al.   JOURNAL OF LIPID RESEARCH

Synthesis of the Rheb and K-Ras4B GTPases

(2010) Yong-Xiang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane Proteins

(2010) Oliver Rocks et al.   CELL

Small-molecule inhibition of APT1 affects Ras localization and signaling

(2010) Frank J Dekker et al.   Nature Chemical Biology

Protein acyl thioesterases (Review)

(2009) Ruth Zeidman et al.   MOLECULAR MEMBRANE BIOLOGY

Dynamic protein palmitoylation in cellular signaling

(2009) Tsuyoshi Iwanaga et al.   PROGRESS IN LIPID RESEARCH

Ras-MAPK Pathway as a Therapeutic Target in Cancer - Emphasis on Bladder Cancer

(2009) Pankaj Dangle et al.   Recent Patents on Anti-Cancer Drug Discovery