Kinetics Studies on the Inhibition Mechanism of Pancreatic α-Amylase by Glycoconjugated 1H-1,2,3-Triazoles: A New Class of Inhibitors with Hypoglycemiant Activity

Inhibition of α-glucosidase and α-amylase by diaryl derivatives of imidazole-thione and 1,2,4-triazole-thiol

(2011) Mahmoud Balba et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles

(2010) Kristýna Slámová et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis of α- and β-d-glucopyranosyl triazoles by CuAAC ‘click chemistry’: reactant tolerance, reaction rate, product structure and glucosidase inhibitory properties

(2010) Simone Dedola et al.   CARBOHYDRATE RESEARCH

Application of click chemistry towards an efficient synthesis of 1,2,3-1H-triazolyl glycohybrids as enzyme inhibitors

(2010) Namarata Anand et al.   CARBOHYDRATE RESEARCH

Synthesis, Biological Activity, and Molecular Modeling Studies of 1H-1,2,3-Triazole Derivatives of Carbohydrates as α-Glucosidases Inhibitors

(2010) Sabrina B. Ferreira et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structures of human pancreatic α-amylase in complex with acarviostatins: Implications for drug design against type II diabetes

(2010) Xiaohong Qin et al.   JOURNAL OF STRUCTURAL BIOLOGY

Natural Products as α-Amylase and α-Glucosidase Inhibitors and their Hypoglycaemic Potential in the Treatment of Diabetes: An Update

(2010) R. Tundis et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Epidemiology of type 2 diabetes

(2010) Nicholas J. Wareham   Endocrinologia y Nutricion

Clinical Utility of Acarbose, an α-Glucosidase Inhibitor in Cardiometabolic Disorders

(2009) Sho-ichi Yamagishi et al.   CURRENT DRUG METABOLISM

Kinetic Analysis and Mechanism on the Inhibition of Chlorogenic Acid and Its Components against Porcine Pancreas α-Amylase Isozymes I and II

(2009) Yusaku Narita et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Structure of a pancreatic α-amylase bound to a substrate analogue at 2.03 Å resolution

(2009) Minxie Qian et al.   PROTEIN SCIENCE

Four acarviosin-containing oligosaccharides identified from Streptomyces coelicoflavus ZG0656 are potent inhibitors of α-amylase

(2008) Peng Geng et al.   CARBOHYDRATE RESEARCH

Mechanistic insights into glycosidase chemistry

(2008) David J Vocadlo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY