A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2

A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A

(2012) Mathew P. Martin et al.   ACS Chemical Biology

Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways

(2012) D. Horiuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a Potential Allosteric Ligand Binding Site in CDK2

(2011) Stephane Betzi et al.   ACS Chemical Biology

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structures of IL-2-inducible T cell Kinase Complexed with Inhibitors: Insights into Rational Drug Design and Activity Regulation

(2010) Alan K. Kutach et al.   Chemical Biology & Drug Design

Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1

(2010) Chenzhong Liao et al.   ACS Medicinal Chemistry Letters

Recent developments in cyclin-dependent kinase biochemical and structural studies

(2009) Aude Echalier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Sunitinib

(2009) Georgios S. Papaetis et al.   BIODRUGS

Quantitative Analyses of Aggregation, Autofluorescence, and Reactivity Artifacts in a Screen for Inhibitors of a Thiol Protease

(2009) Ajit Jadhav et al.   JOURNAL OF MEDICINAL CHEMISTRY

KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

(2009) K. S. Gajiwala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein kinase inhibitors: contributions from structure to clinical compounds

(2009) Louise N. Johnson   QUARTERLY REVIEWS OF BIOPHYSICS

Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes

(2008) Richard M. Angell et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS