Deep epistasis in human metabolism

Epistasis and Its Implications for Personal Genetics

(2009) Jason H. Moore et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Shadows of complexity: what biological networks reveal about epistasis and pleiotropy

(2009) Anna L. Tyler et al.   BIOESSAYS

Genetic Redundancy: New Tricks for Old Genes

(2009) Ran Kafri et al.   CELL

Genome-scale gene/reaction essentiality and synthetic lethality analysis

(2009) Patrick F Suthers et al.   Molecular Systems Biology

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Identification of Potential Pathway Mediation Targets in Toll-like Receptor Signaling

(2009) Fan Li et al.   PLoS Computational Biology

Can single knockouts accurately single out gene functions?

(2008) David Deutscher et al.   BMC Systems Biology

Exploiting the pathway structure of metabolism to reveal high-order epistasis

(2008) Marcin Imielinski et al.   BMC Systems Biology

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Widespread conservation of genetic redundancy during a billion years of eukaryotic evolution

(2008) Tanya Vavouri et al.   TRENDS IN GENETICS

Structural robustness of metabolic networks with respect to multiple knockouts

(2007) Jörn Behre et al.   JOURNAL OF THEORETICAL BIOLOGY