Article
Behavioral Sciences
Taylor E. Stansberry, Anne L. Willliams, Toshikazu Ikuta
Summary: The integrity of the interhemispheric auditory white matter tract is associated with impulsivity, especially sensation seeking. Stronger interhemispheric auditory integration is suggested to be related to greater impulsivity and sensation seeking.
BEHAVIOURAL BRAIN RESEARCH
(2022)
Article
Neurosciences
Alberto Failla, Lauryna Filatovaite, Xiaowan Wang, Sampsa Vanhatalo, Jeroen Dudink, Linda S. de Vries, Manon Benders, Nathan Stevenson, Maria Luisa Tataranno
Summary: The study aimed to investigate the association between bursting interhemispheric synchrony (bIHS) and microstructural development of the corpus callosum (CC) in extremely preterm infants during the first week of life. Results indicated that early cortical synchrony may be affected by morphine, but is not associated with the microstructural development of the CC.
HUMAN BRAIN MAPPING
(2022)
Article
Behavioral Sciences
Nicole Larsen, Brandon T. Craig, Alicia J. Hilderley, Shane Virani, Kara Murias, Brian L. Brooks, Adam Kirton, Helen L. Carlson
Summary: Perinatal stroke affects around 1 in 1000 births and commonly leads to cognitive impairments, with Attention Deficit/Hyperactivity Disorder (ADHD) being a frequent consequence. Using diffusion imaging, researchers found that differences in frontal white matter microstructure were associated with ADHD symptoms and executive functioning in children with perinatal stroke. This suggests that quantified microstructure of frontal white matter via tractography may serve as a relevant biomarker for cognition and behavior in these children.
BRAIN AND BEHAVIOR
(2022)
Article
Geriatrics & Gerontology
Jingchun Liu, Caihong Wang, Jingliang Cheng, Peifang Miao, Zhen Li
Summary: In chronic subcortical stroke, there is increased interhemispheric resting-state functional connectivity (rsFC) between the bilateral primary motor cortex (M1) to compensate for corticospinal tract (CST) impairment, facilitating motor recovery. The FA of the affected M1 fiber in the acute stage showed the most significant correlation with long-term motor recovery, and the compensatory role of M1-M1 rsFC enhancement may start from the subacute stage in stroke patients with CST impairment.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Clinical Neurology
Chaoyang Jin, Shouliang Qi, Yueyang Teng, Chen Li, Yudong Yao, Xiuhang Ruan, Xinhua Wei
Summary: This study investigated the pathophysiological mechanisms of freezing of gait (FOG) in patients with Parkinson's disease by analyzing structural and functional connectivity. The results showed that FOG was associated with white matter abnormalities in specific brain regions and impaired interhemispheric brain connectivity, which correlated with the severity of FOG. Integrating structural and functional MRI data can provide new insights into the mechanisms of FOG in PD.
FRONTIERS IN NEUROLOGY
(2021)
Article
Multidisciplinary Sciences
Gustavo Deco, Morten L. Kringelbach, Aurina Arnatkeviciute, Stuart Oldham, Kristina Sabaroedin, Nigel C. Rogasch, Kevin M. Aquino, Alex Fornito
Summary: Transcriptional variations in excitatory and inhibitory receptor gene expression play a key role in shaping complex neuronal dynamics, yielding both ignition-like dynamics and a wide variance of regional activity time scales. This study demonstrates the viability of using transcriptomic data to constrain models of large-scale brain function.
Article
Neurosciences
Juan F. Quinones, Tommaso Pavan, Xinyang Liu, Christiane M. Thiel, Axel Heep, Andrea Hildebrandt
Summary: This study aimed to reconstruct fiber tracts linking audiovisual integration regions in the newborn brain and assess their similarity to young adults. The results suggest that the fiber bundles were successfully reconstructed in the majority of neonates and showed similarities to adults. Additionally, the study found patterns of early white matter development trajectories and a developmental advantage for females.
Article
Psychology, Mathematical
James A. Grange, Stefanie Schuch
Summary: Evidence-accumulation models are useful for studying cognitive processes, but caution is needed when calculating parameter difference scores as spurious correlations may occur.
BEHAVIOR RESEARCH METHODS
(2023)
Article
Polymer Science
Kuo Chen, Siao-Fong Li, M. Muthukumar
Summary: The research uses fluorescence microscopy to observe the dynamics of DNA molecules trapped in polymer hydrogels under an externally applied electric field. The immobility of DNA molecules in the absence of an electric field is observed, with electrophoretic mobility triggered upon surpassing a threshold electric field strength.
Article
Psychology, Experimental
Pu Fan, Alan C-N Wong, Yetta Kwailing Wong
Summary: This study investigates the role of visual and visual association skills in music sight-reading. The results show that visual fluency for notes, visual-auditory association for notes, and visual-motor association for numbers significantly contribute to sight-reading performance. The findings enhance our understanding of music sight-reading and have educational implications for other domains of skilled reading.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2022)
Article
Geriatrics & Gerontology
Kylie H. Alm, Anja Soldan, Corinne Pettigrew, Andreia V. Faria, Xirui Hou, Hanzhang Lu, Abhay Moghekar, Susumu Mori, Marilyn Albert, Arnold Bakker
Summary: In this study, the independent contributions of structural and functional connectivity markers to individual differences in episodic memory performance in cognitively normal older adults were examined. The results showed that fornix RD, hippocampal cingulum RD, and salience network functional connectivity were significant predictors of memory performance. These findings demonstrated that a combination of structural and functional connectivity markers best accounted for individual variability in episodic memory function in cognitively normal older adults.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Geriatrics & Gerontology
Alica Rogojin, Diana J. J. Gorbet, Kara M. M. Hawkins, Lauren E. E. Sergio
Summary: Visuomotor impairments have been observed in preclinical Alzheimer's disease (AD), especially in individuals with a family history of dementia and APOE e4 carriers. This study examined the relationship between grey and white matter changes and non-standard visuomotor performance, as well as the influence of APOE status, family history, and sex on these brain-behavior relationships.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Oncology
Yangying Kuang, Xiaojia Wu, Hua Lai, Zhigang Wang, Qiang Lei, Weijia Zhong, Ya Yang, Chen Deng, Zhiming Zhou
Summary: This study found that OHE patients had decreased volumes in all subregions of the corpus callosum, and the decreased fractional anisotropy of CC-5 was correlated with decreased VMHC in specific brain regions. Additionally, the FA values of CC-5 and the volumes of CC-3, CC-4, and CC-5 showed correlations with neuropsychological performance in OHE patients, indicating that impairment of interhemispheric white matter pathways may disrupt functional connectivity and neurocognitive performance.
ANNALS OF TRANSLATIONAL MEDICINE
(2021)
Article
Neurosciences
N. S. D'Souza, M. B. Nebel, D. Crocetti, J. Robinson, N. Wymbs, S. H. Mostofsky, A. Venkataraman
Summary: The framework combines rs-fMRI connectivity and DTI tractography data to extract biomarkers predictive of behavior, using a generative model of connectomics data and a deep network to predict behavioral scores. Joint optimization strategy estimates basis networks, subject-specific loadings, and neural network weights. The hybrid model outperforms state-of-the-art approaches in clinical outcome prediction and learns interpretable multimodal neural signatures of brain organization.
Article
Geriatrics & Gerontology
David J. Robles, Ammar Dharani, Kenneth A. Rostowsky, Nikhil N. Chaudhari, Van Ngo, Fan Zhang, Lauren J. O'Donnell, Lauren Green, Nasim Sheikh-Bahaei, Helena C. Chui, Andrei Irimia
Summary: Age is linearly associated with white matter degradation, likely not only due to injury but also to cumulative effects of other pathologies and their interactions with injury. As time passes, the degradation of brain white matter will result in age-dependent deficits in information processing speed, interhemispheric communication, motor coordination, visual acuity, sensory integration, reading speed/comprehension, executive function, personality, and memory.
Article
Neurosciences
Sunny Nigam, Masanori Shimono, Shinya Ito, Fang-Chin Yeh, Nicholas Timme, Maxym Myroshnychenko, Christopher C. Lapish, Zachary Tosi, Pawel Hottowy, Wesley C. Smith, Sotiris C. Masmanidis, Alan M. Litke, Olaf Sporns, John M. Beggs
JOURNAL OF NEUROSCIENCE
(2016)
Article
Biochemical Research Methods
Nicholas M. Timme, Shinya Ito, Maxym Myroshnychenko, Sunny Nigam, Masanori Shimono, Fang-Chin Yeh, Pawel Hottowy, Alan M. Litke, John M. Beggs
PLOS COMPUTATIONAL BIOLOGY
(2016)
Article
Multidisciplinary Sciences
Masanori Shimono, Naomichi Hatano
SCIENTIFIC REPORTS
(2018)
Article
Neurosciences
Masanori Shimono, John M. Beggs
Article
Neurosciences
Masanori Shimono, Keiichi Kitajo, Tsunehiro Takeda
HUMAN BRAIN MAPPING
(2011)
Article
Physics, Multidisciplinary
Nir Friedman, Shinya Ito, Braden A. W. Brinkman, Masanori Shimono, R. E. Lee DeVille, Karin A. Dahmen, John M. Beggs, Thomas C. Butler
PHYSICAL REVIEW LETTERS
(2012)
Article
Multidisciplinary Sciences
Alexander Nakhnikian, George V. Rebec, Leslie M. Grasse, Lucas L. Dwiel, Masanori Shimono, John M. Beggs
Article
Multidisciplinary Sciences
Masanori Shimono
SCIENTIFIC REPORTS
(2013)
Article
Biochemical Research Methods
Motoki Kajiwara, Ritsuki Nomura, Felix Goetze, Masanori Kawabata, Yoshikazu Isomura, Tatsuya Akutsu, Masanori Shimono
Summary: This study evaluated the controlling ability of inhibitory neurons in comparison with excitatory neurons by conducting simultaneous electrical recording and quantitative evaluation of neuronal interactions. The results showed that inhibitory neurons have higher controlling ability, especially in deeper layers of the cortex. The limited number of neurons with high controlling ability may be more effective in modeling and treating imbalanced disease states in the brain.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Neurosciences
Masanori Shimono, Kazuhisa Niki
BRAIN CONNECTIVITY
(2013)
Article
Physics, Fluids & Plasmas
Masanori Shimono, Takashi Owaki, Kaoru Amano, Keiichi Kitajo, Tsunehiro Takeda