Journal
CEPHALALGIA
Volume 34, Issue 14, Pages 1187-1192Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0333102414532554
Keywords
Migraine; depression; comorbidity; allodynia; LUMINA
Categories
Funding
- Netherlands Organization for Scientific Research (NWO) [VIDI 917.11.319]
- European Community (EC)
Ask authors/readers for more resources
Introduction There is a strong association between migraine and depression. The aim of this study is to identify migraine-specific factors involved in this association. Methods We conducted a cross-sectional study in a large, well-defined cohort of migraine patients (n=2533). We assessed lifetime depression using validated questionnaires, and diagnosed migraine based on the International Classification of Headache Disorders III-beta criteria. Multivariate regression analyses were conducted. Results Of the 2533 migraineurs that were eligible, 1137 (45%) suffered from lifetime depression. The following independent factors were associated with an increased depression prevalence: i) migraine-specific risk factors: high migraine attack frequency and the presence of allodynia, ii) general factors: being a bad sleeper, female gender, high BMI, being single, smoking, and a low alcohol consumption. Conclusion This study identified allodynia, in addition to high migraine attack frequency, as a new migraine-specific factor associated with depression.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available