Pearls and pitfalls in human pharmacological models of migraine: 30 years' experience

3,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase (nNOS) inhibitors

(2012) Subhash C. Annedi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dural mast cell degranulation is a putative mechanism for headache induced by PACAP-38

(2012) Michael Baun et al.   CEPHALALGIA

Prostaglandin E2 induces immediate migraine-like attack in migraine patients without aura

(2012) Maria Antonova et al.   CEPHALALGIA

Rescue Therapy for Acute Migraine, Part 2: Neuroleptics, Antihistamines, and Others

(2012) Nancy E. Kelley et al.   HEADACHE

Peripheral and central alterations of pituitary adenylate cyclase activating polypeptide-like immunoreactivity in the rat in response to activation of the trigeminovascular system

(2012) Bernadett Tuka et al.   PEPTIDES

Pro-inflammatory and vasoconstricting prostanoid PGF2α causes no headache in man

(2011) Maria Antonova et al.   CEPHALALGIA

Lack of correlation between vasodilatation and pharmacologically induced immediate headache in healthy subjects

(2011) Messoud Ashina et al.   CEPHALALGIA

Headache and prolonged dilatation of the middle meningeal artery by PACAP38 in healthy volunteers

(2011) Faisal Mohammad Amin et al.   CEPHALALGIA

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine

(2011) David J Hewitt et al.   CEPHALALGIA

Calcitonin Gene-Related Peptide Does Not Cause Migraine Attacks in Patients With Familial Hemiplegic Migraine

(2011) Jakob M. Hansen et al.   HEADACHE

The pharmacological effect of BGC20-1531, a novel prostanoid EP4 receptor antagonist, in the Prostaglandin E2 human model of headache

(2011) Maria Antonova et al.   JOURNAL OF HEADACHE AND PAIN

Increased Susceptibility to Cortical Spreading Depression in the Mouse Model of Familial Hemiplegic Migraine Type 2

(2011) Loredana Leo et al.   PLoS Genetics

Evidence for a vascular factor in migraine

(2010) Mohammad S. Asghar et al.   ANNALS OF NEUROLOGY

Activation of central trigeminovascular neurons by cortical spreading depression

(2010) XiChun Zhang et al.   ANNALS OF NEUROLOGY

The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men

(2010) Bart J. Van der Schueren et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Lack of efficacy of the selective iNOS inhibitor GW274150 in prophylaxis of migraine headache

(2010) Hans Olav Høivik et al.   CEPHALALGIA

Discrepancy between strong cephalic arterial dilatation and mild headache caused by prostaglandin D2 (PGD2)

(2010) Troels Wienecke et al.   CEPHALALGIA

CGRP receptor antagonist olcegepant (BIBN4096BS) does not prevent glyceryl trinitrate-induced migraine

(2010) JF Tvedskov et al.   CEPHALALGIA

Increase in CGRP- and nNOS-immunoreactive neurons in the rat trigeminal ganglion after infusion of an NO donor

(2010) Anne Dieterle et al.   CEPHALALGIA

Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura

(2010) Jakob Møller Hansen et al.   CEPHALALGIA

Activation of Meningeal Nociceptors by Cortical Spreading Depression: Implications for Migraine with Aura

(2010) X. Zhang et al.   JOURNAL OF NEUROSCIENCE

Coexisting typical migraine in familial hemiplegic migraine

(2010) J. M. Hansen et al.   NEUROLOGY

Dilation by CGRP of middle meningeal artery and reversal by sumatriptan in normal volunteers

(2010) M. S. Asghar et al.   NEUROLOGY

The PACAP receptor: A novel target for migraine treatment

(2010) Henrik W. Schytz et al.   Neurotherapeutics

Microemboli may link spreading depression, migraine aura, and patent foramen ovale

(2009) Ala Nozari et al.   ANNALS OF NEUROLOGY

Finding New Drug Targets for the Treatment of Migraine Attacks

(2009) J Olesen et al.   CEPHALALGIA

Nitroglycerin provocation in normal subjects is not a useful human migraine model?

(2009) JF Tvedskov et al.   CEPHALALGIA

Prostaglandin E2 (PGE2) Induces Headache in Healthy Subjects

(2009) T Wienecke et al.   CEPHALALGIA

Trigger factors in migraine with aura

(2009) AW Hauge et al.   CEPHALALGIA

Prostaglandin I2 (epoprostenol) triggers migraine-like attacks in migraineurs

(2009) T Wienecke et al.   CEPHALALGIA

Migraine and the Environment

(2009) Deborah I. Friedman et al.   HEADACHE

Nitroglycerin Headache and Nitroglycerin-Induced Primary Headaches From 1846 and Onwards: A Historical Overview and an Update

(2009) Peer C. Tfelt-Hansen et al.   HEADACHE

Cerebral Haemodynamic Response or Excitability is not Affected by Sildenafil

(2009) Christina Kruuse et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Does the Unfavorable Pharmacokinetic and Pharmacodynamic Profile of the iNOS Inhibitor GW273629 Lead to Inefficacy in Acute Migraine?

(2009) B. J. Van der Schueren et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Migraine headache is not associated with cerebral or meningeal vasodilatation—a 3T magnetic resonance angiography study

(2008) G. G. Schoonman et al.   BRAIN

PACAP38 induces migraine-like attacks in patients with migraine without aura

(2008) Henrik Winther Schytz et al.   BRAIN

Familial Hemiplegic Migraine Type 2 does not Share Hypersensitivity to Nitric Oxide with Common Types of Migraine

(2008) JM Hansen et al.   CEPHALALGIA

Familial Hemiplegic Migraine Type 1 Shows no Hypersensitivity to Nitric Oxide

(2008) JM Hansen et al.   CEPHALALGIA

Vasoactive Intestinal Peptide Causes Marked Cephalic Vasodilation, but does not Induce Migraine

(2008) A Rahmann et al.   CEPHALALGIA

Intracranial hemodynamics during intravenous infusion of glyceryl trinitrate

(2008) H. K. Iversen et al.   JOURNAL OF HEADACHE AND PAIN

Nitric oxide-induced headache may arise from extracerebral arteries as judged from tolerance to isosorbide-5-mononitrate

(2008) Ingelise Christiansen et al.   JOURNAL OF HEADACHE AND PAIN

Involvement of calcitonin gene-related peptide in migraine: regional cerebral blood flow and blood flow velocity in migraine patients

(2008) L. H. Lassen et al.   JOURNAL OF HEADACHE AND PAIN

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

(2008) Tony W Ho et al.   LANCET

Calcitonin gene-related peptide does not cause the familial hemiplegic migraine phenotype

(2008) J. M. Hansen et al.   NEUROLOGY

Prostacyclin (epoprostenol) induces headache in healthy subjects

(2008) Troels Wienecke et al.   PAIN