Article
Clinical Neurology
Chun Yuen Fong, Wai Him Crystal Law, Johannes Jacobus Fahrenfort, Jason J. Braithwaite, Ali Mazaheri
Summary: This study found that migraineurs had lower alpha power before the onset of stimuli and higher alpha suppression after stimuli. These findings suggest the hyperresponsiveness of the visual cortex in migraine sufferers and may be related to dysfunction of the GABAergic inhibitory mechanism.
JOURNAL OF HEADACHE AND PAIN
(2022)
Article
Medicine, Research & Experimental
Heiko Pohl, Marius Moisa, Hans-H. Jung, Kathrin Brenner, Jessica Aschmann, Franz Riederer, Christian C. Ruff, Jean Schoenen, Roger Luechinger, Lukas Widmer, Jens A. Petersen, Andreas R. Gantenbein, Peter S. Sandor, Lars Michels
Summary: Self-administered anodal tDCS over the visual cortex significantly decreased the number of monthly migraine days in episodic migraine. The study provides evidence of tDCS effectiveness in reducing migraine attacks.
Article
Psychology, Multidisciplinary
Louisa J. Rinaldi, Rebecca Smees, Jamie Ward, Julia Simner
Summary: This study investigates the well-being profile of children with misophonia and develops the first validated questionnaire for children. The results show that children with misophonia have significantly elevated levels of anxiety and obsessive compulsive traits, as well as poorer life satisfaction and health-related quality of life. There are no differences in creative self-construct. These findings call for greater awareness of misophonia and more therapeutic support for children.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Construction & Building Technology
A. Wilkins
Summary: Photophobia, commonly associated with migraines, can be triggered by various factors such as bright light, flicker, spatial patterns, and colors. Understanding the underlying principles and utilizing methods to reduce discomfort is essential in managing photophobia.
LIGHTING RESEARCH & TECHNOLOGY
(2021)
Article
Clinical Neurology
Vincenzo Di Stefano, Salvatore Iacono, Andrea Gagliardo, Bruna Maggio, Giuliana Guggino, Massimo Gangitano, Roberto Monastero, Vito Renato Maggio, Nadia Bolognini, Filippo Brighina
Summary: This study found that patients with fibromyalgia have reduced and almost abolished fission illusion, while there were no differences between groups in fusion trials. Migraine did not affect the fission and the fusion illusions. These findings suggest that patients with fibromyalgia have visual cortical hyperexcitability, which may play an important role in the pathophysiology of fibromyalgia.
PAIN RESEARCH & MANAGEMENT
(2022)
Article
Computer Science, Artificial Intelligence
Lorenzo Bisi, Davide Santambrogio, Federico Sandrelli, Andrea Tirinzoni, Brian D. Ziebart, Marcello Restelli
Summary: This paper introduces a unified framework to optimize various risk measures, including conditional value-at-risk, utility functions, and mean-variance. By leveraging recent theoretical results on state augmentation, the decision-making process is transformed to optimize in the transformed environment, and a simple risk-sensitive meta-algorithm is presented to optimize risk-neutral policy. Extensive experiments demonstrate the advantages of this approach over existing ad-hoc methodologies in different domains.
ARTIFICIAL INTELLIGENCE
(2022)
Article
Neurosciences
Adisa Kuburas, Bianca N. Mason, Benjamin Hing, Anne-Sophie Wattiez, Alyssa S. Reis, Levi P. Sowers, Cristina Moldovan Loomis, Leon F. Garcia-Martinez, Andrew F. Russo
Summary: CGRP and PACAP have emerged as mediators of migraine, inducing migraine-like symptoms through independent pathways in mice. Monoclonal antibodies targeting PACAP may be effective in patients unresponsive to CGRP-based therapeutics.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Psychology, Developmental
L. J. Rinaldi, J. Simner, S. Koursarou, J. Ward
Summary: Autistic traits are indeed elevated in individuals with misophonia, which is related to autism, sensory sensitivities, and the specific features of misophonia.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Multidisciplinary Sciences
Rachel Bernhard, Justin de Benedictis-Kessner
Summary: The study found that women who narrowly lose elections are not more likely to quit politics than men. This suggests that women's decision-making differs from men's at the point of entry into politics, rather than at the point of reentry.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Clinical Neurology
Clare L. Fraser
Summary: Until recently, there has been limited research on visual snow syndrome, but current studies suggest that it is caused by cortical dysfunction. Although visual snow syndrome is often associated with migraines, they are distinct clinical entities.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2022)
Review
Biochemistry & Molecular Biology
Maria E. de Lahoz, Paloma Barjola, Irene Pelaez, David Ferrera, Roberto Fernandes-Magalhaes, Francisco Mercado
Summary: This article provides a review of the characteristics and functional significance of CNV in migraine patients, exploring differences between adults and children. The findings suggest that CNV shows significant abnormalities a few days before migraine attacks and may serve as a potential neural marker for predicting pain attacks. However, the evidence in children is limited and inconsistent, highlighting the need for further research.
Article
Clinical Neurology
Nara Ikumi, Xim Cerda-Company, Angela Marti-Marca, Adria Vila-Ballo, Edoardo Caronna, Victor Jose Gallardo, Patricia Pozo-Rosich
Summary: The study found that avoidance behavior may exacerbate phonophobia, and the current methods for measuring phonophobia need to be revised.
Article
Clinical Neurology
Ozan E. Eren, Ruth Ruscheweyh, Veronika Rauschel, Thomas Eggert, Christoph J. Schankin, Andreas Straube
Summary: This study compared the inhibition of the primary visual cortex in patients with VSS and age- and migraine-matched controls. The results showed suppression of visual accuracy at the 100-ms interval, but no significant differences were found between VSS patients and controls.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Yi Zhou, Hui Li, Yanlu Jia, Jun Wu, Jinshuai Yang, Chunling Liu
Summary: This study analyzed the microstructural features of sleep in patients with vestibular migraine and migraine, and hypothesized the pathophysiological mechanism between vestibular migraine and sleep disorders. The results showed that patients with vestibular migraine had poor sleep quality, thalamic-cortical hyperfunction, and an active arousal system.
Article
Clinical Neurology
Anne-Sophie Wattiez, Olivia J. Gaul, Adisa Kuburas, Erik Zorilla, Jayme S. Waite, Bianca N. Mason, William C. Castonguay, Mengya Wang, Bennett R. Robertson, Andrew F. Russo
Summary: The study aimed to test the validity of CGRP-induced migraine-like symptoms in mice by comparing responses during the active and inactive phases. The results showed that peripheral administration of CGRP decreased mouse activity, induced light aversive behavior, and spontaneous pain, regardless of the time of day or night. This suggests that preclinical assessment of migraine-like phenotypes can be done during the more convenient inactive phase of mice.
JOURNAL OF HEADACHE AND PAIN
(2021)
Article
Behavioral Sciences
Sarah M. Haigh, Timothy A. Keller, Nancy J. Minshew, Shaun M. Eack
Article
Clinical Neurology
Alexandra Vieira, Ian van der Linde, Peter Bright, Arnold Wilkins
Article
Behavioral Sciences
Sarah M. Haigh, Yaara Endevelt-Shapira, Marlene Behrmann
Review
Clinical Neurology
Arnold J. Wilkins, Sarah M. Haigh, Omar A. Mahroo, Gordon T. Plant
Summary: The article discusses photophobia in migraine and suggests that a cortical mechanism may provide a parsimonious explanation for discomfort from various forms of visual stimulation. Future research comparing retinal and cortical contributions to photophobia in migraine may help identify biomarkers and treatment mechanisms.
Article
Behavioral Sciences
Mario Brinciotti, Arnold J. Wilkins, Olivier Penacchio, Maria Matricardi
Summary: The study showed that pattern-sensitive epilepsy patients often self-induced seizures by using uncomfortable visual stimuli as triggers. However, these uncomfortable images were transformed into pleasant stimuli for many patients after enjoyable epileptic symptoms were induced.
EPILEPSY & BEHAVIOR
(2021)
Article
Psychology, Experimental
Marena S. Manierka, Rachel Rezaei, Samantha Palacios, Sarah M. Haigh, Jeffrey J. Hutsler
Summary: The study found that fluctuations in individuals' mood state can impact the recognition of specific facial expressions, with increased positive mood improving recognition of scared expressions but worsening recognition of happy expressions. This suggests that minor mood fluctuations in a neurotypical population affect emotion recognition and should be taken into consideration by researchers and clinicians assessing FER skills.
Review
Clinical Neurology
Robert S. Fisher, Jayant N. Acharya, Fiona Mitchell Baumer, Jacqueline A. French, Pasquale Parisi, Jessica H. Solodar, Jerzy P. Szaflarski, Liu Lin Thio, Benjamin Tolchin, Arnold J. Wilkins, Dorothee Kasteleijn-Nolst Trenite
Summary: Light stimulation can trigger seizures in certain individuals, especially in young people and those with specific forms of epilepsy. Photosensitive seizures can coexist with spontaneous seizures and have a genetic component. The exact mechanisms of photosensitive seizures are still unclear, but specific triggers such as flashes or color changes can provoke seizures. Prevention strategies include avoiding triggers, covering one eye, keeping a safe distance from screens, reducing contrast, and taking certain antiseizure medications. Visually-induced seizures pose significant public health risks, requiring ongoing scientific research, regulation, and public education.
Article
Ophthalmology
James M. Gilchrist, Peter M. Allen, Laura Monger, Krithica Srinivasan, Arnold Wilkins
Summary: The Wilkins Rate of Reading Test (WRRT) is a reliable tool for measuring differences in reading speed between individuals influenced by visual and ocular motor factors. The precision of the test varies among samples, with an average of 7.2 wcpm, providing a basis for setting a standard for monitoring changes in reading speed in individuals.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2021)
Article
Psychology, Developmental
Sarah M. Haigh, Laura Van Key, Pat Brosseau, Shaun M. Eack, David Leitman, Dean F. Salisbury, Marlene Behrmann
Summary: Sensory abnormalities that indicate instability are common in both autism and schizophrenia. This study found that trial-to-trial variability in sensory neural responses, particularly in the amplitude, is greater in autism and schizophrenia compared to controls. However, there were no differences in the timing of neural responses between the groups.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Neurosciences
Wendy A. Torrens, Jenna N. Pablo, Jorja Shires, Sarah M. Haigh, Marian E. Berryhill
Summary: Individuals diagnosed with schizophrenia spectrum disorders (SSD) show both hyporeactivity and subjective experiences of sensory hyperexcitability. This study tested a non-clinical population for schizotypy traits and a measure of sensory hyperexcitability, finding that higher schizotypy traits were associated with more illusions reported in the Pattern Glare Test. The disorganized factor of the Schizotypal Personality Questionnaire predicted the number of illusions reported. These findings highlight the potential for studying non-clinical samples to inform clinically relevant research.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Book Review
Ophthalmology
Arnold Wilkins
Review
Neurosciences
Sarah M. Haigh, Marian E. Berryhill, Alexandrea Kilgore-Gomez, Michael Dodd
Summary: The search for reliable biomarkers of schizophrenia is important and should involve assessing multiple biomarkers simultaneously. Investigating biomarkers in individuals with schizophrenia-related traits in the general population can accelerate progress in understanding the mechanisms of schizophrenia. There is a lack of research on certain types of memory biomarkers in schizotypy, which presents an opportunity for researchers to address gaps in knowledge and potentially uncover new insights.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Construction & Building Technology
A. Wilkins
Summary: Photophobia, commonly associated with migraines, can be triggered by various factors such as bright light, flicker, spatial patterns, and colors. Understanding the underlying principles and utilizing methods to reduce discomfort is essential in managing photophobia.
LIGHTING RESEARCH & TECHNOLOGY
(2021)
Article
Clinical Neurology
Alireza Chamanzar, Sarah M. Haigh, Pulkit Grover, Marlene Behrmann
Summary: The study reveals alterations in cortical patterns of coherence in individuals with migraine during interictal period, showing faster color detection performance and lower spatial coherence of alpha-band activity, especially in frontal clusters. Abnormal patterns of EEG coherence in migraineurs during visual and auditory stimuli, as well as at rest, may be associated with cortical hyper-responsivity characteristic of abnormal sensory processing in migraine.
BRAIN COMMUNICATIONS
(2021)
Article
Construction & Building Technology
S. W. Park, C-S Lee, H. R. Kang, H. S. Pak, A. Wilkins
LIGHTING RESEARCH & TECHNOLOGY
(2020)