Malaria adhesins: structure and function

A quantitative assay for binding and inhibition of Plasmodium falciparum Erythrocyte Binding Antigen 175 reveals high affinity binding depends on both DBL domains

(2014) Nichole D. Salinas et al.   PROTEIN EXPRESSION AND PURIFICATION

Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC

(2014) Joseph D. Batchelor et al.   PLoS Pathogens

Broadly Neutralizing Antiviral Antibodies

(2013) Davide Corti et al.   Annual Review of Immunology

Molecular Architecture of a Complex between an Adhesion Protein from the Malaria Parasite and Intracellular Adhesion Molecule 1

(2013) Alan Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Biochemical Characterization ofPlasmodium falciparum12 (Pf12) Reveals a Unique Interdomain Organization and the Potential for an Antiparallel Arrangement withPf41

(2013) Michelle L. Tonkin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical Analysis of thePlasmodium falciparumErythrocyte-binding Antigen-175 (EBA175)-Glycophorin-A Interaction

(2013) Madushi Wanaguru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis for Sialic Acid-dependent Receptor Recognition by thePlasmodium falciparumInvasion Protein Erythrocyte-binding Antigen-140/BAEBL

(2013) Brian M. Malpede et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion

(2013) Daniel Y. Bargieri et al.   Nature Communications

Whole Genome Sequencing of Field Isolates Reveals a Common Duplication of the Duffy Binding Protein Gene in Malagasy Plasmodium vivax Strains

(2013) Didier Menard et al.   PLoS Neglected Tropical Diseases

De Novo Assembly of a Field Isolate Genome Reveals Novel Plasmodium vivax Erythrocyte Invasion Genes

(2013) James Hester et al.   PLoS Neglected Tropical Diseases

Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development

(2013) Sowmya Sampath et al.   PLoS Pathogens

Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175

(2013) Edwin Chen et al.   PLoS Pathogens

Analysis of the Conformation and Function of the Plasmodium falciparum Merozoite Proteins MTRAP and PTRAMP

(2012) Onyinyechukwu Uchime et al.   EUKARYOTIC CELL

Crystal and Solution Structures ofPlasmodium falciparumErythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion

(2012) Daniel H. Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into Duffy Binding-like Domains through the Crystal Structure and Function of the Merozoite Surface Protein MSPDBL2 fromPlasmodium falciparum

(2012) Anthony N. Hodder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

(2012) Alan F. Cowman et al.   JOURNAL OF CELL BIOLOGY

Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41

(2012) Tana Taechalertpaisarn et al.   PLoS One

Structure of the Plasmodium 6-cysteine s48/45 domain

(2012) S. A. Arredondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shape change in the receptor for gliding motility in Plasmodium sporozoites

(2012) G. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unexpected fold in the circumsporozoite protein target of malaria vaccines

(2012) M. B. Doud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Semaphorin-7A Is an Erythrocyte Receptor for P. falciparum Merozoite-Specific TRAP Homolog, MTRAP

(2012) S. Josefin Bartholdson et al.   PLoS Pathogens

Structural and Functional Insights into the Malaria Parasite Moving Junction Complex

(2012) Brigitte Vulliez-Le Normand et al.   PLoS Pathogens

Structural Basis for the ABO Blood-Group Dependence of Plasmodium falciparum Rosetting

(2012) Inès Vigan-Womas et al.   PLoS Pathogens

A role for heparan sulfate proteoglycans inPlasmodium falciparumsporozoite invasion of anopheline mosquito salivary glands

(2011) Jennifer S. Armistead et al.   BIOCHEMICAL JOURNAL

Design and Immunogenicity of a Novel Synthetic Antigen Based on the Ligand Domain of the Plasmodium vivax Duffy Binding Protein

(2011) Francis B. Ntumngia et al.   Clinical and Vaccine Immunology

Structural Characterization of the Erythrocyte Binding Domain of the Reticulocyte Binding Protein Homologue Family of Plasmodium yoelii

(2011) Ardina Grüber et al.   INFECTION AND IMMUNITY

The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host

(2011) Alida Coppi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC

(2011) Joseph D Batchelor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of a Plasmodium falciparum PfEMP1 rosetting domain reveals a role for the N-terminal segment in heparin-mediated rosette inhibition

(2011) A. Juillerat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding ofPlasmodiummerozoite proteins RON2 and AMA1 triggers commitment to invasion

(2011) Prakash Srinivasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites

(2011) Mauld Lamarque et al.   PLoS Pathogens

Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut

(2010) Ingrid Rupp et al.   CELL RESEARCH

Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA

(2010) A. Srivastava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three Members of the 6-cys Protein Family of Plasmodium Play a Role in Gamete Fertility

(2010) Melissa R. van Dijk et al.   PLoS Pathogens

Plasmodium sporozoite invasion of the mosquito salivary gland

(2009) Anil Kumar Ghosh et al.   CURRENT OPINION IN MICROBIOLOGY

Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications

(2009) J. Alexandra Rowe et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Polymorphisms in Erythrocyte Binding Antigens 140 and 181 Affect Function and Binding but Not Receptor Specificity in Plasmodium falciparum

(2009) A. G. Maier et al.   INFECTION AND IMMUNITY

Structure of thePlasmodium falciparumCircumsporozoite Protein, a Leading Malaria Vaccine Candidate

(2009) Matthew L. Plassmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Comparison of Two CSPG-Binding DBL Domains from the VAR2CSA Protein Important in Malaria during Pregnancy

(2009) Pongsak Khunrae et al.   JOURNAL OF MOLECULAR BIOLOGY

Malaria Parasite Invasion of the Mosquito Salivary Gland Requires Interaction between the Plasmodium TRAP and the Anopheles Saglin Proteins

(2009) Anil K. Ghosh et al.   PLoS Pathogens

The Structure of a Chondroitin Sulfate-binding Domain Important in Placental Malaria

(2008) Matthew K. Higgins   JOURNAL OF BIOLOGICAL CHEMISTRY

Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites

(2008) Jun Cao et al.   PARASITOLOGY INTERNATIONAL

Apical membrane antigen 1: a malaria vaccine candidate in review

(2008) Edmond J. Remarque et al.   TRENDS IN PARASITOLOGY

Host-cell invasion by malaria parasites: insights from Plasmodium and Toxoplasma

(2008) Jake Baum et al.   TRENDS IN PARASITOLOGY

The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure

(2008) Michael M. Klein et al.   PLoS Pathogens

Malarial EBA-175 Region VI Crystallographic Structure Reveals a KIX-Like Binding Interface

(2007) Chrislaine Withers-Martinez et al.   JOURNAL OF MOLECULAR BIOLOGY