Hsp90-dependent regulatory circuitry controlling temperature-dependent fungal development and virulence

Cryptococcus neoformans Rim101 Is Associated with Cell Wall Remodeling and Evasion of the Host Immune Responses

(2013) T. R. O'Meara et al.   mBio

Calcineurin Governs Thermotolerance and Virulence of Cryptococcus gattii

(2013) Ying-Lien Chen et al.   G3-Genes Genomes Genetics

Candida albicans Commensalism and Pathogenicity Are Intertwined Traits Directed by a Tightly Knit Transcriptional Regulatory Circuit

(2013) J. Christian Pérez et al.   PLOS BIOLOGY

Pho85, Pcl1, and Hms1 Signaling Governs Candida albicans Morphogenesis Induced by High Temperature or Hsp90 Compromise

(2012) Rebecca S. Shapiro et al.   CURRENT BIOLOGY

Identification of an Hsp90 mutation that selectively disrupts cAMP/PKA signaling in Saccharomyces cerevisiae

(2012) Gary A. Flom et al.   CURRENT GENETICS

Heat Shock Protein 90 Is Required for Conidiation and Cell Wall Integrity in Aspergillus fumigatus

(2012) Frédéric Lamoth et al.   EUKARYOTIC CELL

Titan Cells Confer Protection from Phagocytosis in Cryptococcus neoformans Infections

(2012) Laura H. Okagaki et al.   EUKARYOTIC CELL

Hsp90 regulatesParacoccidioides brasiliensisproliferation and ROS levels under thermal stress and cooperates with calcineurin to control yeast to mycelium dimorphism

(2012) Tatiana G. F. Matos et al.   MEDICAL MYCOLOGY

Modelling the Regulation of Thermal Adaptation in Candida albicans, a Major Fungal Pathogen of Humans

(2012) Michelle D. Leach et al.   PLoS One

Calcineurin Is Required for Pseudohyphal Growth, Virulence, and Drug Resistance in Candida lusitaniae

(2012) Jing Zhang et al.   PLoS One

The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance

(2012) Rebecca S. Shapiro et al.   PLoS One

Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

(2012) Nicole Robbins et al.   Cell Reports

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in Candida glabrata

(2012) Ying-Lien Chen et al.   G3-Genes Genomes Genetics

Global Analysis of the Evolution and Mechanism of Echinocandin Resistance in Candida glabrata

(2012) Sheena D. Singh-Babak et al.   PLoS Pathogens

Calcineurin Controls Drug Tolerance, Hyphal Growth, and Virulence in Candida dubliniensis

(2011) Ying-Lien Chen et al.   EUKARYOTIC CELL

Cryptococcal Titan Cell Formation Is Regulated by G-Protein Signaling in Response to Multiple Stimuli

(2011) Laura H. Okagaki et al.   EUKARYOTIC CELL

Discovery of a Role for Hsp82 in Histoplasma Virulence through a Quantitative Screen for Macrophage Lethality

(2011) Jessica A. Edwards et al.   INFECTION AND IMMUNITY

Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in Candida albicans

(2011) Heather Senn et al.   MOLECULAR BIOLOGY OF THE CELL

Association of Calcineurin with the COPI Protein Sec28 and the COPII Protein Sec13 Revealed by Quantitative Proteomics

(2011) Lukasz Kozubowski et al.   PLoS One

The Fungal Pathogen Candida albicans Autoinduces Hyphal Morphogenesis by Raising Extracellular pH

(2011) S. Vylkova et al.   mBio

Adaptations of Candida albicans for Growth in the Mammalian Intestinal Tract

(2010) Ari Rosenbach et al.   EUKARYOTIC CELL

Divergent Protein Kinase A isoforms co-ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus

(2010) Kevin K. Fuller et al.   MOLECULAR MICROBIOLOGY

HSP90 at the hub of protein homeostasis: emerging mechanistic insights

(2010) Mikko Taipale et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cryptococcal Cell Morphology Affects Host Cell Interactions and Pathogenicity

(2010) Laura H. Okagaki et al.   PLoS Pathogens

Fungal Cell Gigantism during Mammalian Infection

(2010) Oscar Zaragoza et al.   PLoS Pathogens

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

(2009) Benjamin J Park et al.   AIDS

Epidemiology and Outcomes of Candidemia in 2019 Patients: Data from the Prospective Antifungal Therapy Alliance Registry

(2009) David L. Horn et al.   CLINICAL INFECTIOUS DISEASES

Hsp90 Orchestrates Temperature-Dependent Candida albicans Morphogenesis via Ras1-PKA Signaling

(2009) Rebecca S. Shapiro et al.   CURRENT BIOLOGY

Elucidating the Pathogenesis of Spores from the Human Fungal Pathogen Cryptococcus neoformans

(2009) S. S. Giles et al.   INFECTION AND IMMUNITY

Vertebrate Endothermy Restricts Most Fungi as Potential Pathogens

(2009) Vincent A. Robert et al.   JOURNAL OF INFECTIOUS DISEASES

Hsp90 Governs Echinocandin Resistance in the Pathogenic Yeast Candida albicans via Calcineurin

(2009) Sheena D. Singh et al.   PLoS Pathogens

The stress responsive and morphologically regulated hsp90 gene from Paracoccidioides brasiliensis is essential to cell viability

(2008) André M Nicola et al.   BMC MICROBIOLOGY

Calcineurin Target CrzA Regulates Conidial Germination, Hyphal Growth, and Pathogenesis ofAspergillus fumigatus

(2008) Robert A. Cramer et al.   EUKARYOTIC CELL

Schizosaccharomyces pombe Hsp90/Git10 Is Required for Glucose/cAMP Signaling

(2008) M. A. Alaamery et al.   GENETICS

Metabolic adaptation inCryptococcus neoformansduring early murine pulmonary infection

(2008) Guanggan Hu et al.   MOLECULAR MICROBIOLOGY