Ehrlichia type IV secretion effector ECH0825 is translocated to mitochondria and curbs ROS and apoptosis by upregulating host MnSOD

1-oxoeudesm-11(13)-ene-12,8α-lactone-induced apoptosis via ROS generation and mitochondria activation in MCF-7 cells

(2011) Min Cui et al.   ARCHIVES OF PHARMACAL RESEARCH

Ehrlichia chaffeensis Induces Monocyte Inflammatory Responses through MyD88, ERK, and NF-κB but Not through TRIF, Interleukin-1 Receptor 1 (IL-1R1)/IL-18R1, or Toll-Like Receptors

(2011) Koshiro Miura et al.   INFECTION AND IMMUNITY

How does the oxidative burst of macrophages kill bacteria? Still an open question

(2011) James M. Slauch   MOLECULAR MICROBIOLOGY

Ehrlichia chaffeensis Transcriptome in Mammalian and Arthropod Hosts Reveals Differential Gene Expression and Post Transcriptional Regulation

(2011) Jeeba A. Kuriakose et al.   PLoS One

Identification of Anaplasma marginale Type IV Secretion System Effector Proteins

(2011) Svetlana Lockwood et al.   PLoS One

Global Proteomic Analysis of Two Tick-Borne Emerging Zoonotic Agents: Anaplasma Phagocytophilum and Ehrlichia Chaffeensis

(2011) Mingqun Lin et al.   Frontiers in Microbiology

Two-step and one-step secretion mechanisms in Gram-negative bacteria: contrasting the type IV secretion system and the chaperone-usher pathway of pilus biogenesis

(2010) Ana Toste Rêgo et al.   BIOCHEMICAL JOURNAL

Higher expression of ferritin protects Chlamydia trachomatis infected HeLa 229 cells from reactive oxygen species mediated cell death

(2010) Harsh Vardhan et al.   Biochemistry and Cell Biology

Anaplasma phagocytophilum and Ehrlichia chaffeensis type IV secretion and Ank proteins

(2010) Yasuko Rikihisa et al.   CURRENT OPINION IN MICROBIOLOGY

Cyclic di-GMP Signaling Regulates Invasion by Ehrlichia chaffeensis of Human Monocytes

(2010) Y. Kumagai et al.   JOURNAL OF BACTERIOLOGY

Distinct Host Species Correlate with Anaplasma phagocytophilum ankA Gene Clusters

(2010) W. Scharf et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Time Dependent Bladder Apoptosis Induced by Acute Bladder Outlet Obstruction and Subsequent Emptying is Associated with Decreased MnSOD Expression and Bcl-2/Bax Ratio

(2010) Wen Ji Li et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity

(2010) Yan Liu et al.   MICROBES AND INFECTION

Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells

(2010) Yasuko Rikihisa   NATURE REVIEWS MICROBIOLOGY

Anaplasma phagocytophilum Ats-1 Is Imported into Host Cell Mitochondria and Interferes with Apoptosis Induction

(2010) Hua Niu et al.   PLoS Pathogens

Type IV Secretion System of Anaplasma phagocytophilum and Ehrlichia chaffeensis

(2009) Yasuko Rikihisa et al.   Annals of the New York Academy of Sciences

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics

Nuclear Translocated Ehrlichia chaffeensis Ankyrin Protein Interacts with a Specific Adenine-Rich Motif of Host Promoter and Intronic Alu Elements

(2009) B. Zhu et al.   INFECTION AND IMMUNITY

Neurobehavioral impairments, generation of oxidative stress and release of pro-apoptotic factors after chronic exposure to sulphur mustard in mouse brain

(2009) Deep Raj Sharma et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Molecular events involved in cellular invasion by Ehrlichia chaffeensis and Anaplasma phagocytophilum

(2009) Yasuko Rikihisa   VETERINARY PARASITOLOGY

Regulation of Type IV Secretion Apparatus Genes during Ehrlichia chaffeensis Intracellular Development by a Previously Unidentified Protein

(2008) Z. Cheng et al.   JOURNAL OF BACTERIOLOGY

Four VirB6 Paralogs and VirB9 Are Expressed and Interact in Ehrlichia chaffeensis-Containing Vacuoles

(2008) W. Bao et al.   JOURNAL OF BACTERIOLOGY

Biological Roles for the NOX Family NADPH Oxidases

(2008) William M. Nauseef   JOURNAL OF BIOLOGICAL CHEMISTRY

An intracellular wave of cytochrome c propagates and precedes Bax redistribution during apoptosis

(2008) L. Lartigue et al.   JOURNAL OF CELL SCIENCE

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-κB pathways and mitochondrial protective mechanisms

(2008) Zhiwei Xu et al.   TOXICOLOGY

Staying alive: bacterial inhibition of apoptosis during infection

(2008) Christina S. Faherty et al.   TRENDS IN MICROBIOLOGY