Eating the strangers within: host control of intracellular bacteria via xenophagy

How cells deploy ubiquitin and autophagy to defend their cytosol from bacterial invasion

(2011) Felix Randow   Autophagy

The ubiquitin-binding adaptor proteins p62/SQSTM1 and NDP52 are recruited independently to bacteria-associated microdomains to target Salmonella to the autophagy pathway

(2011) Marija Cemma et al.   Autophagy

The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against Salmonella

(2011) Shun Kageyama et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

(2010) Hannah E.J. Polson et al.   Autophagy

Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

(2010) Ju Huang et al.   Autophagy

Genome-wide Analysis of the Host Intracellular Network that Regulates Survival of Mycobacterium tuberculosis

(2010) Dhiraj Kumar et al.   CELL

A Diacylglycerol-Dependent Signaling Pathway Contributes to Regulation of Antibacterial Autophagy

(2010) Shahab Shahnazari et al.   Cell Host & Microbe

Autophagosomes can support Yersinia pseudotuberculosis replication in macrophages

(2010) Kevin Moreau et al.   CELLULAR MICROBIOLOGY

Autophagy in infection

(2010) Vojo Deretic   CURRENT OPINION IN CELL BIOLOGY

Delivery of Cytosolic Components by Autophagic Adaptor Protein p62 Endows Autophagosomes with Unique Antimicrobial Properties

(2010) Marisa Ponpuak et al.   IMMUNITY

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages

(2010) Scott B Berger et al.   NATURE IMMUNOLOGY

Listeriolysin O Is Necessary and Sufficient to Induce Autophagy during Listeria monocytogenes Infection

(2010) Nicole Meyer-Morse et al.   PLoS One

Dissemination of invasiveSalmonellavia bacterial-induced extrusion of mucosal epithelia

(2010) Leigh A. Knodler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling

(2010) Dong-Min Shin et al.   PLoS Pathogens

Autophagy, Immunity, and Microbial Adaptations

(2009) Vojo Deretic et al.   Cell Host & Microbe

Shigella Phagocytic Vacuolar Membrane Remnants Participate in the Cellular Response to Pathogen Invasion and Are Regulated by Autophagy

(2009) Nicolas Dupont et al.   Cell Host & Microbe

New insights intoChlamydiaintracellular survival mechanisms

(2009) Jordan L. Cocchiaro et al.   CELLULAR MICROBIOLOGY

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

Yersinia pestis Can Reside in Autophagosomes and Avoid Xenophagy in Murine Macrophages by Preventing Vacuole Acidification

(2009) C. Pujol et al.   INFECTION AND IMMUNITY

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Listeria monocytogenes ActA-mediated escape from autophagic recognition

(2009) Yuko Yoshikawa et al.   NATURE CELL BIOLOGY

Autophagy genes in immunity

(2009) Herbert W Virgin et al.   NATURE IMMUNOLOGY

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

(2009) Ronald S. Flannagan et al.   NATURE REVIEWS MICROBIOLOGY

Activation of antibacterial autophagy by NADPH oxidases

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Initial Step of GAS-Containing Autophagosome-Like Vacuoles Formation Requires Rab7

(2009) Hitomi Yamaguchi et al.   PLoS Pathogens

Atg5-Independent Sequestration of Ubiquitinated Mycobacteria

(2009) Cathleen A. Collins et al.   PLoS Pathogens

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

The Salmonella-containing vacuole—Moving with the times

(2008) Olivia Steele-Mortimer   CURRENT OPINION IN MICROBIOLOGY

Toll-like receptors control autophagy

(2008) Mónica A Delgado et al.   EMBO JOURNAL

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

(2008) Elizabeth L. Axe et al.   JOURNAL OF CELL BIOLOGY

Listeriolysin O allows Listeria monocytogenes replication in macrophage vacuoles

(2008) Cheryl L. Birmingham et al.   NATURE

Autophagic control of listeria through intracellular innate immune recognition in drosophila

(2008) Tamaki Yano et al.   NATURE IMMUNOLOGY

Microarray Analysis of Human Monocytes Infected with Francisella tularensis Identifies New Targets of Host Response Subversion

(2008) Jonathan P. Butchar et al.   PLoS One

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

(2008) P. K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNAi Screen of Endoplasmic Reticulum–Associated Host Factors Reveals a Role for IRE1α in Supporting Brucella Replication

(2008) Qing-Ming Qin et al.   PLoS Pathogens