Mechanisms of Blood Brain Barrier Disruption by Different Types of Bacteria, and Bacterial–Host Interactions Facilitate the Bacterial Pathogen Invading the Brain

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

(2017) Federico Iovino et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The role of non-endothelial cells on the penetration of nanoparticles through the blood brain barrier

(2017) Rui Pedro Moura et al.   PROGRESS IN NEUROBIOLOGY

Pathophysiology of acute meningitis caused by Streptococcus pneumoniae and adjunctive therapy approaches

(2017) Tatiana Barichello et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Host–pathogen interactions in bacterial meningitis

(2016) Kelly S. Doran et al.   ACTA NEUROPATHOLOGICA

Staphylococcus aureus-mediated blood-brain barrier injury: anin vitrohuman brain microvascular endothelial cell model

(2016) Alisha McLoughlin et al.   CELLULAR MICROBIOLOGY

How Does Streptococcus pneumoniae Invade the Brain?

(2016) Federico Iovino et al.   TRENDS IN MICROBIOLOGY

Pathogenesis of Streptococcus urinary tract infection depends on bacterial strain and β-hemolysin/cytolysin that mediates cytotoxicity, cytokine synthesis, inflammation and virulence

(2016) Sophie Y. Leclercq et al.   Scientific Reports

A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury

(2015) C. Whidbey et al.   EMBO Molecular Medicine

Tumour necrosis factor-α-mediated disruption of cerebrovascular endothelial barrier integrityin vitroinvolves the production of proinflammatory interleukin-6

(2015) Keith D. Rochfort et al.   JOURNAL OF NEUROCHEMISTRY

Cytokine-mediated dysregulation of zonula occludens-1 properties in human brain microvascular endothelium

(2015) Keith D. Rochfort et al.   MICROVASCULAR RESEARCH

Blood–Brain Barrier and Bilirubin: Clinical Aspects and Experimental Data

(2014) Maria Alexandra Brito et al.   ARCHIVES OF MEDICAL RESEARCH

PECAM-1: regulator of endothelial junctional integrity

(2014) Jamie R. Privratsky et al.   CELL AND TISSUE RESEARCH

Platelet Endothelial Cell Adhesion Molecule-1, a Putative Receptor for the Adhesion of Streptococcus pneumoniae to the Vascular Endothelium of the Blood-Brain Barrier

(2014) Federico Iovino et al.   INFECTION AND IMMUNITY

Differential Induction of Inflammatory Cytokines and Reactive Oxygen Species in Murine Peritoneal Macrophages and Resident Fresh Bone Marrow Cells by Acute Staphylococcus aureus Infection: Contribution of Toll-Like Receptor 2 (TLR2)

(2014) Ajeya Nandi et al.   INFLAMMATION

Signalling or binding: the role of the platelet-activating factor receptor in invasive pneumococcal disease

(2013) Federico Iovino et al.   CELLULAR MICROBIOLOGY

A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta

(2013) Christopher Whidbey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Acute Bacterial Meningitis with Coincident Methamphetamine Use: A Case Report and Review of the Literature

(2013) Michael Heninger et al.   JOURNAL OF FORENSIC SCIENCES

The surface proteins InlA and InlB are interdependently required for polar basolateral invasion by Listeria monocytogenes in a human model of the blood–cerebrospinal fluid barrier

(2013) Tim Gründler et al.   MICROBES AND INFECTION

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus

(2013) Timothy J. Foster et al.   NATURE REVIEWS MICROBIOLOGY

Interactions between Blood-Borne Streptococcus pneumoniae and the Blood-Brain Barrier Preceding Meningitis

(2013) Federico Iovino et al.   PLoS One

Circulating concentrations, cerebral output of the CINC-1 and blood–brain barrier disruption in Wistar rats after pneumococcal meningitis induction

(2012) T. Barichello et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Defense at the border: the blood–brain barrier versus bacterial foreigners

(2012) Nina M van Sorge et al.   Future Microbiology

Group B streptococcal disease in infants aged younger than 3 months: systematic review and meta-analysis

(2012) Karen M Edmond et al.   LANCET

Overexpression of actin-depolymerizing factor blocks oxidized low-density lipoprotein-induced mouse brain microvascular endothelial cell barrier dysfunction

(2012) Jun Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Pili of Gram-positive bacteria: roles in host colonization

(2012) Camille Danne et al.   RESEARCH IN MICROBIOLOGY

Binding of Glycoprotein Srr1 of Streptococcus agalactiae to Fibrinogen Promotes Attachment to Brain Endothelium and the Development of Meningitis

(2012) Ho Seong Seo et al.   PLoS Pathogens

Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

(2011) Anna Carrano et al.   ANTIOXIDANTS & REDOX SIGNALING

Vascular colonization by Neisseria meningitidis

(2011) Keira Melican et al.   CURRENT OPINION IN MICROBIOLOGY

Hcp Family Proteins Secreted via the Type VI Secretion System Coordinately Regulate Escherichia coli K1 Interaction with Human Brain Microvascular Endothelial Cells

(2011) Yan Zhou et al.   INFECTION AND IMMUNITY

Contribution of Lethal Toxin and Edema Toxin to the Pathogenesis of Anthrax Meningitis

(2011) Celia M. Ebrahimi et al.   INFECTION AND IMMUNITY

Oxidative Stress, Cytokine/Chemokine and Disruption of Blood–Brain Barrier in Neonate Rats After Meningitis by Streptococcus agalactiae

(2011) Tatiana Barichello et al.   NEUROCHEMICAL RESEARCH

Bacillus anthracis Protease InhA Increases Blood-Brain Barrier Permeability and Contributes to Cerebral Hemorrhages

(2011) Dhritiman V. Mukherjee et al.   PLoS One

Bacterial Pili exploit integrin machinery to promote immune activation and efficient blood-brain barrier penetration

(2011) Anirban Banerjee et al.   Nature Communications

Meningococcus Hijacks a β2-Adrenoceptor/β-Arrestin Pathway to Cross Brain Microvasculature Endothelium

(2010) Mathieu Coureuil et al.   CELL

Activation of brain endothelium by pneumococcal neuraminidase NanA promotes bacterial internalization

(2010) Anirban Banerjee et al.   CELLULAR MICROBIOLOGY

Epidemiology, Diagnosis, and Antimicrobial Treatment of Acute Bacterial Meningitis

(2010) M. C. Brouwer et al.   CLINICAL MICROBIOLOGY REVIEWS

IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice

(2010) John S. Cho et al.   JOURNAL OF CLINICAL INVESTIGATION

The surface protein HvgA mediates group B streptococcus hypervirulence and meningeal tropism in neonates

(2010) Asmaa Tazi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Penetration of the blood–brain barrier by Staphylococcus aureus: contribution of membrane-anchored lipoteichoic acid

(2010) Tamsin R. Sheen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

TNF-α, IL-1β, IL-6, and cinc-1 levels in rat brain after meningitis induced by Streptococcus pneumoniae

(2010) Tatiana Barichello et al.   JOURNAL OF NEUROIMMUNOLOGY

A kinetic study of the cytokine/chemokines levels and disruption of blood-brain barrier in infant rats after pneumococcal meningitis

(2010) Tatiana Barichello et al.   JOURNAL OF NEUROIMMUNOLOGY

Staphylococcus aureus Meningitis

(2010) Javier Aguilar et al.   MEDICINE

Regulation of CovR expression in Group B Streptococcus impacts blood-brain barrier penetration

(2010) Annalisa Lembo et al.   MOLECULAR MICROBIOLOGY

The population genetics of commensal Escherichia coli

(2010) Olivier Tenaillon et al.   NATURE REVIEWS MICROBIOLOGY

The Listeria monocytogenes InlC protein interferes with innate immune responses by targeting the I B kinase subunit IKK 

(2010) E. Gouin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neisseria meningitidis Induces Brain Microvascular Endothelial Cell Detachment from the Matrix and Cleavage of Occludin: A Role for MMP-8

(2010) Alexandra Schubert-Unkmeir et al.   PLoS Pathogens

Importance of cerebrospinal fluid analysis in stat laboratory

(2009) Tze-Kiong Er et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Nitric oxide/cGMP signalling inducesEscherichia coliK1 receptor expression and modulates the permeability in human brain endothelial cell monolayers during invasion

(2009) Rahul Mittal et al.   CELLULAR MICROBIOLOGY

Oxidative stress and myeloperoxidase activity during bacterial meningitis: Effects of febrile episodes and the BBB permeability

(2009) Dijana Miric et al.   CLINICAL BIOCHEMISTRY

The InhA Metalloproteases of Bacillus cereus Contribute Concomitantly to Virulence

(2009) E. Guillemet et al.   JOURNAL OF BACTERIOLOGY

Penetration of the Blood-Brain Barrier by Bacillus anthracis Requires the pXO1-Encoded BslA Protein

(2009) C. M. Ebrahimi et al.   JOURNAL OF BACTERIOLOGY

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

(2009) Carlos J. Orihuela et al.   JOURNAL OF CLINICAL INVESTIGATION

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion

(2009) Satoshi Uchiyama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Group B Streptococcal Serine‐Rich Repeat 1 Glycoprotein Mediates Penetration of the Blood‐Brain Barrier

(2009) Nina M. van Sorge et al.   JOURNAL OF INFECTIOUS DISEASES

Activation of plasminogen activator inhibitor implicates protease InhA in the acute-phase response to Bacillus anthracis infection

(2009) M.-C. Chung et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Evaluation of capsular and acapsular strains of S. aureus in an experimental brain abscess model

(2009) Nilufer Esen et al.   JOURNAL OF NEUROIMMUNOLOGY

Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates

(2009) James P Watt et al.   LANCET

BslA, the S-layer adhesin ofB. anthracis, is a virulence factor for anthrax pathogenesis

(2009) Justin Kern et al.   MOLECULAR MICROBIOLOGY

Pathogenic neisseriae: surface modulation, pathogenesis and infection control

(2009) Mumtaz Virji   NATURE REVIEWS MICROBIOLOGY

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Mechanisms of meningeal invasion by a bacterial extracellular pathogen, the example of Neisseria meningitidis

(2009) Olivier Join-Lambert et al.   PROGRESS IN NEUROBIOLOGY

Meningococcal Type IV Pili Recruit the Polarity Complex to Cross the Brain Endothelium

(2009) Mathieu Coureuil et al.   SCIENCE

The blood-brain barrier in brain homeostasis and neurological diseases

(2008) Nicolas Weiss et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction

(2008) Helen Marriott et al.   CURRENT MOLECULAR MEDICINE

Antibodies for the treatment of bacterial infections: current experience and future prospects

(2008) Christopher Bebbington et al.   CURRENT OPINION IN BIOTECHNOLOGY

The Interaction of Streptococcus pneumoniae with Plasmin Mediates Transmigration across Endothelial and Epithelial Monolayers by Intercellular Junction Cleavage

(2008) C. Attali et al.   INFECTION AND IMMUNITY

Degradation of Circulating von Willebrand Factor and Its Regulator ADAMTS13 Implicates SecretedBacillus anthracisMetalloproteases in Anthrax Consumptive Coagulopathy

(2008) Myung-Chul Chung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlation of CSF neuroinflammatory molecules with leptomeningeal cortical subcortical white matter fractional anisotropy in neonatal meningitis

(2008) Abhishek Yadav et al.   MAGNETIC RESONANCE IMAGING

Spatial localization of bacteria controls coagulation of human blood by 'quorum acting'

(2008) Christian J Kastrup et al.   Nature Chemical Biology

Mechanisms of microbial traversal of the blood–brain barrier

(2008) Kwang Sik Kim   NATURE REVIEWS MICROBIOLOGY

Proinflammatory cytokine levels in the serum and cerebrospinal fluid of tuberculous meningitis patients

(2008) G. Nagesh Babu et al.   NEUROSCIENCE LETTERS

Anthrax Toxins Inhibit Neutrophil Signaling Pathways in Brain Endothelium and Contribute to the Pathogenesis of Meningitis

(2008) Nina M. van Sorge et al.   PLoS One

From bone marrow to microglia: barriers and avenues

(2008) Nathalie Davoust et al.   TRENDS IN IMMUNOLOGY

PCR detection of Staphylococcal enterotoxins (SEs) N, O, P, Q, R, U, and survey of SE types in Staphylococcus aureus isolates from food-poisoning cases in Taiwan

(2007) Yu-Cheng Chiang et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY