mRNA Expression Levels of PGC-1α in a Transgenic and a Toxin Model of Huntington’s Disease

A single nucleotide polymorphism in the coding region of PGC-1α is a male-specific modifier of Huntington disease age-at-onset in a large European cohort

(2014) Patrick Weydt et al.   BMC Neurology

Role of the peroxisome proliferator-activated receptors (PPAR)-α, β/δ and γ triad in regulation of reactive oxygen species signaling in brain

(2013) Stepan Aleshin et al.   BIOLOGICAL CHEMISTRY

PGC-1α, mitochondrial dysfunction, and Huntington's disease

(2013) Ashu Johri et al.   FREE RADICAL BIOLOGY AND MEDICINE

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

(2013) Maria Damiano et al.   HUMAN MOLECULAR GENETICS

PGC-1  is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis

(2013) J. Eschbach et al.   HUMAN MOLECULAR GENETICS

Regulation of mitochondrial biogenesis and PGC-1α under cellular stress

(2013) Tina Wenz   MITOCHONDRION

Neuropathology of Partial PGC-1α Deficiency Recapitulates Features of Mitochondrial Encephalopathies but Not of Neurodegenerative Diseases

(2013) Levente Szalardy et al.   Neurodegenerative Diseases

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

(2012) Jorge L. Ruas et al.   CELL

The Role of PGC-1α in the Pathogenesis of Neurodegenerative Disorders

(2012) Krisztina Rona-Voros et al.   CURRENT DRUG TARGETS

Population stratification may bias analysis of PGC-1α as a modifier of age at Huntington disease motor onset

(2012) Eliana Marisa Ramos et al.   HUMAN GENETICS

A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset†

(2012) Selma M. Soyal et al.   HUMAN MOLECULAR GENETICS

Mitogen- and stress-activated protein kinase 1-induced neuroprotection in Huntington's disease: role on chromatin remodeling at the PGC-1-alpha promoter

(2011) Elodie Martin et al.   HUMAN MOLECULAR GENETICS

Characterization of Novel Peroxisome Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) Isoform in Human Liver

(2011) Thomas K. Felder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

(2011) Hong Van B Che et al.   Molecular Neurodegeneration

Truncated Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α Splice Variant Is Severely Altered in Huntington’s Disease

(2011) Ashu Johri et al.   Neurodegenerative Diseases

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

(2010) J. Kim et al.   HUMAN MOLECULAR GENETICS

Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation

(2010) R. K. Chaturvedi et al.   HUMAN MOLECULAR GENETICS

Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA- and ROS-dependent pathway

(2009) G Liot et al.   CELL DEATH AND DIFFERENTIATION

Impaired PGC-1α function in muscle in Huntington's disease

(2009) Rajnish K. Chaturvedi et al.   HUMAN MOLECULAR GENETICS

Alternative mRNA Splicing Produces a Novel Biologically Active Short Isoform of PGC-1α

(2009) Yubin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The gene coding for PGC-1α modifies age at onset in Huntington's Disease

(2009) Patrick Weydt et al.   Molecular Neurodegeneration

PGC-1alpha as modifier of onset age in Huntington disease

(2009) Elahe Taherzadeh-Fard et al.   Molecular Neurodegeneration

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS