LGR5 is a Proneural Factor and is Regulated by OLIG2 in Glioma Stem-Like Cells

Brain Tumor Stem-Like Cells Identified by Neural Stem Cell Marker CD15

(2014) Xing-gang Mao et al.   Translational Oncology

LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem-Like Cells

(2012) Susumu Nakata et al.   BRAIN PATHOLOGY

Self-Renewal Does Not Predict Tumor Growth Potential in Mouse Models of High-Grade Glioma

(2012) Lindy E. Barrett et al.   CANCER CELL

Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in Glioma

(2011) Chong Liu et al.   CELL

Overexpression of ZNF217 in glioblastoma contributes to the maintenance of glioma stem cells regulated by hypoxia-inducible factors

(2011) Xing-gang Mao et al.   LABORATORY INVESTIGATION

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

LGR5 Is a Negative Regulator of Tumourigenicity, Antagonizes Wnt Signalling and Regulates Cell Adhesion in Colorectal Cancer Cell Lines

(2011) Francesca Walker et al.   PLoS One

An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells

(2010) Qing Sheng et al.   CANCER CELL

A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

(2010) Ruihuan Chen et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Sertad1 Plays an Essential Role in Developmentaland Pathological Neuron Death

(2010) S. C. Biswas et al.   JOURNAL OF NEUROSCIENCE

The Thyroid Hormone Receptor α1 Protein Is Expressed in Embryonic Postmitotic Neurons and Persists in Most Adult Neurons

(2010) Karin Wallis et al.   MOLECULAR ENDOCRINOLOGY

An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates

(2010) Ting Guo et al.   NATURE NEUROSCIENCE

Erratum: Neural stem cell systems: physiological players or in vitro entities?

(2010) Luciano Conti et al.   NATURE REVIEWS NEUROSCIENCE

Expression of Mutant p53 Proteins Implicates a Lineage Relationship between Neural Stem Cells and Malignant Astrocytic Glioma in a Murine Model

(2009) Yuan Wang et al.   CANCER CELL

p34SEI-1 Inhibits Apoptosis through the Stabilization of the X-Linked Inhibitor of Apoptosis Protein: p34SEI-1 as a Novel Target for Anti-Breast Cancer Strategies

(2009) S.-W. Hong et al.   CANCER RESEARCH

Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology

(2009) L. A.M. Gravendeel et al.   CANCER RESEARCH

Cancer Stem Cells: Controversial or Just Misunderstood?

(2009) Craig T. Jordan   Cell Stem Cell

SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma

(2009) Myung Jin Son et al.   Cell Stem Cell

Stable Expression of Neurogenin 1 Induces LGR5, a Novel Stem Cell Marker, in an Immortalized Human Neural Stem Cell Line HB1.F3

(2009) Jun-ichi Satoh et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

IRF4: Immunity. Malignancy! Therapy?

(2009) A. L. Shaffer et al.   CLINICAL CANCER RESEARCH

Cell types to order: temporal specification of CNS stem cells

(2009) Hideyuki Okano et al.   CURRENT OPINION IN NEUROBIOLOGY

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine

(2009) Marie Isabelle Garcia et al.   DEVELOPMENTAL BIOLOGY

IL1RAPL1 controls inhibitory networks during cerebellar development in mice

(2009) Frédéric Gambino et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Role of the cytoplasmic domain of the L1 cell adhesion molecule in brain development

(2009) Yukiko Nakamura et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Identification of the role of Smad interacting protein 1 (SIP1) in glioma

(2009) Microgene Xia et al.   JOURNAL OF NEURO-ONCOLOGY

Transforming growth-interacting factor (TGIF ) regulates proliferation and differentiation of human myeloid leukemia cells

(2009) Rizwan Hamid et al.   Molecular Oncology

Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors

(2009) Eve Seuntjens et al.   NATURE NEUROSCIENCE

In situ hybridization reveals developmental regulation of ErbB1-4 mRNA expression in mouse midbrain: Implication of ErbB receptors for dopaminergic neurons

(2009) Y. Abe et al.   NEUROSCIENCE

G-Protein-Coupled Receptor GPR49 is Up-regulated in Basal Cell Carcinoma and Promotes Cell Proliferation and Tumor Formation

(2008) Keiji Tanese et al.   AMERICAN JOURNAL OF PATHOLOGY

Inactivation of gadd45a Sensitizes Epithelial Cancer Cells to Ionizing Radiation In vivo Resulting in Prolonged Survival

(2008) X. Lu et al.   CANCER RESEARCH

Targeting Cancer Stem Cells through L1CAM Suppresses Glioma Growth

(2008) S. Bao et al.   CANCER RESEARCH

Progress on Potential Strategies to Target Brain Tumor Stem Cells

(2008) Xing-gang Mao et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

DOCK10-Mediated Cdc42 Activation Is Necessary for Amoeboid Invasion of Melanoma Cells

(2008) Gilles Gadea et al.   CURRENT BIOLOGY

Quantitative analysis of mitotic Olig2 cells in adult human brain and gliomas: Implications for glioma histogenesis and biology

(2008) Wootack Rhee et al.   GLIA

Absence of 2-Hydroxylated Sphingolipids Is Compatible with Normal Neural Development But Causes Late-Onset Axon and Myelin Sheath Degeneration

(2008) I. Zoller et al.   JOURNAL OF NEUROSCIENCE

Zebrafish orthologue of mental retardation protein IL1RAPL1 regulates presynaptic differentiation

(2008) Tomoyuki Yoshida et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis

(2008) Hye-Jung Han et al.   NATURE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

Lgr5 marks cycling, yet long-lived, hair follicle stem cells

(2008) Viljar Jaks et al.   NATURE GENETICS

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

(2008) Bastian G. Brinkmann et al.   NEURON

Olig2-Induced Neural Stem Cell Differentiation Involves Downregulation of Wnt Signaling and Induction of Dickkopf-1 Expression

(2008) Sung-Min Ahn et al.   PLoS One