Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system

Parkin-mediated K63-linked polyubiquitination: A signal for targeting misfolded proteins to the aggresome-autophagy pathway

(2014) James A. Olzmann et al.   Autophagy

Regulation of proteolysis by human deubiquitinating enzymes

(2013) Ziad M. Eletr et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 leads to early-onset progressive neurodegeneration

(2013) Kaya Bilguvar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of ubiquitin carboxyl terminal hydrolase impairs multiple pathways during eye development in Drosophila melanogaster

(2012) Dang Thi Phuong Thao et al.   CELL AND TISSUE RESEARCH

Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking

(2012) Samuel M. Lee et al.   JOURNAL OF CELL BIOLOGY

Parkinson's Disease: Genetics and Pathogenesis

(2011) Joshua M. Shulman et al.   Annual Review of Pathology-Mechanisms of Disease

DUBs and cancer: The role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors

(2011) Sajjad Hussain et al.   CELL CYCLE

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy

(2010) Lih-Shen Chin et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Ubiquitin carboxyl-terminal hydrolase L1 is required for maintaining the structure and function of the neuromuscular junction

(2010) F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice

(2010) G. Poulogiannis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

(2009) Roland Hjerpe et al.   EMBO REPORTS

Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling

(2009) D. Sha et al.   HUMAN MOLECULAR GENETICS

PGP 9.5 and Cyclin D1 Coexpression in Cutaneous Squamous Cell Carcinomas

(2009) Aikaterini Mastoraki et al.   INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY

Printor, a Novel TorsinA-interacting Protein Implicated in Dystonia Pathogenesis

(2009) Lisa M. Giles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies

(2009) Selvaraju Veeriah et al.   NATURE GENETICS

UCHL1 (PGP 9.5): Neuronal biomarker and ubiquitin system protein

(2009) Ian N.M. Day et al.   PROGRESS IN NEUROBIOLOGY

Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function

(2009) Eleanor J. Davison et al.   PROTEOMICS

Aberrant Folding of Pathogenic Parkin Mutants

(2008) Julia S. Schlehe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Essential Role of Sequestosome 1/p62 in Regulating Accumulation of Lys63-ubiquitinated Proteins

(2008) Marie W. Wooten et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypertonia-Associated Protein Trak1 Is a Novel Regulator of Endosome-to-Lysosome Trafficking

(2008) Elizabeth Webber et al.   JOURNAL OF MOLECULAR BIOLOGY

Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity

(2008) B.J. Walters et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The neuronal ubiquitin-proteasome system: Murine models and their neurological phenotype

(2008) Paula van Tijn et al.   PROGRESS IN NEUROBIOLOGY