Bacterial chemoreceptors and chemoeffectors

Sinorhizobium meliloti Chemoreceptor McpU Mediates Chemotaxis toward Host Plant Exudates through Direct Proline Sensing

(2014) Benjamin A. Webb et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

New Insights into Bacterial Chemoreceptor Array Structure and Assembly from Electron Cryotomography

(2014) Ariane Briegel et al.   BIOCHEMISTRY

Functional Suppression of HAMP Domain Signaling Defects in the E. coli Serine Chemoreceptor

(2014) Run-Zhi Lai et al.   JOURNAL OF MOLECULAR BIOLOGY

A soluble mutant of the transmembrane receptor Af1503 features strong changes in coiled-coil periodicity

(2014) Marcus D. Hartmann et al.   JOURNAL OF STRUCTURAL BIOLOGY

Axial helix rotation as a mechanism for signal regulation inferred from the crystallographic analysis of the E. coli serine chemoreceptor

(2014) Hedda U. Ferris et al.   JOURNAL OF STRUCTURAL BIOLOGY

The HAMP signal-conversion domain: static two-state or dynamic three-state?

(2014) Valley Stewart   MOLECULAR MICROBIOLOGY

Defining a Key Receptor–CheA Kinase Contact and Elucidating Its Function in the Membrane-Bound Bacterial Chemosensory Array: A Disulfide Mapping and TAM-IDS Study

(2013) Kene N. Piasta et al.   BIOCHEMISTRY

The 3.2 Å Resolution Structure of a Receptor:CheA:CheW Signaling Complex Defines Overlapping Binding Sites and Key Residue Interactions within Bacterial Chemosensory Arrays

(2013) Xiaoxiao Li et al.   BIOCHEMISTRY

Residues at the Cytoplasmic End of Transmembrane Helix 2 Determine the Signal Output of the TarEc Chemoreceptor

(2013) Christopher A. Adase et al.   BIOCHEMISTRY

Precision Sensing by Two Opposing Gradient Sensors: How Does Escherichia coli Find its Preferred pH Level?

(2013) Bo Hu et al.   BIOPHYSICAL JOURNAL

Prolonged stimuli alter the bacterial chemosensory clusters

(2013) Vered Frank et al.   MOLECULAR MICROBIOLOGY

Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non-protein amino acid gamma-aminobutyrate (GABA)

(2013) Miriam Rico-Jiménez et al.   MOLECULAR MICROBIOLOGY

HAMP domain structural determinants for signalling and sensory adaptation in Tsr, theEscherichia coliserine chemoreceptor

(2013) Peter Ames et al.   MOLECULAR MICROBIOLOGY

The mobility of two kinase domains in theEscherichia colichemoreceptor array varies with signalling state

(2013) Ariane Briegel et al.   MOLECULAR MICROBIOLOGY

Discovery of novel chemoeffectors and rational design of Escherichia coli chemoreceptor specificity

(2013) S. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phenylalanine rotameric switch for signal-state control in bacterial chemoreceptors

(2013) Davi R. Ortega et al.   Nature Communications

HAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors

(2013) Michael V. Airola et al.   PLOS BIOLOGY

Ligand Affinity and Kinase Activity Are Independent of Bacterial Chemotaxis Receptor Concentration: Insight into Signaling Mechanisms

(2012) Fe C. Sferdean et al.   BIOCHEMISTRY

The Residue Composition of the Aromatic Anchor of the Second Transmembrane Helix Determines the Signaling Properties of the Aspartate/Maltose Chemoreceptor Tar of Escherichia coli

(2012) Christopher A. Adase et al.   BIOCHEMISTRY

HAMP Domain Signal Relay Mechanism in a Sensory Rhodopsin-Transducer Complex

(2012) Jihong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Responses of Pseudomonas putida to toxic aromatic carbon sources

(2012) Tino Krell et al.   JOURNAL OF BIOTECHNOLOGY

CheA–Receptor Interaction Sites in Bacterial Chemotaxis

(2012) Xiqing Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Opposite responses by different chemoreceptors set a tunable preference point inEscherichia colipH taxis

(2012) Yiling Yang et al.   MOLECULAR MICROBIOLOGY

Bacterial chemoreceptor arrays are hexagonally packed trimers of receptor dimers networked by rings of kinase and coupling proteins

(2012) A. Briegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of chemoreceptor arrays revealed by cryoelectron tomography of Escherichia coli minicells

(2012) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for chemoreceptors with bimodular ligand-binding regions harboring two signal-binding sites

(2012) E. Pineda-Molina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Proposed Mechanism for the pH-Sensing Helicobacter pylori Chemoreceptor TlpB

(2012) Emily Goers Sweeney et al.   STRUCTURE

Thalassospira sp. Isolated from the Oligotrophic Eastern Mediterranean Sea Exhibits Chemotaxis toward Inorganic Phosphate during Starvation

(2011) Annemarie Hütz et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Transmembrane Signaling of Chemotaxis Receptor Tar: Insights from Molecular Dynamics Simulation Studies

(2011) Hahnbeom Park et al.   BIOPHYSICAL JOURNAL

Thermal Robustness of Signaling in Bacterial Chemotaxis

(2011) Olga Oleksiuk et al.   CELL

Responding to chemical gradients: bacterial chemotaxis

(2011) Victor Sourjik et al.   CURRENT OPINION IN CELL BIOLOGY

Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response

(2011) Cezar M Khursigara et al.   EMBO JOURNAL

Bacterial chemotaxis towards aromatic hydrocarbons in Pseudomonas

(2011) Jesús Lacal et al.   ENVIRONMENTAL MICROBIOLOGY

Transmembrane signal transduction in archaeal phototaxis: The sensory rhodopsin II-transducer complex studied by electron paramagnetic resonance spectroscopy

(2011) Johann P. Klare et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Phenol Sensing by Escherichia coli Chemoreceptors: a Nonclassical Mechanism

(2011) H. T. Pham et al.   JOURNAL OF BACTERIOLOGY

Mutational Analysis of the Control Cable That Mediates Transmembrane Signaling in the Escherichia coli Serine Chemoreceptor

(2011) S. Kitanovic et al.   JOURNAL OF BACTERIOLOGY

Different Conformations of the Kinase-On and Kinase-Off Signaling States in the Aer HAMP Domain

(2011) K. J. Watts et al.   JOURNAL OF BACTERIOLOGY

Mutational Analysis of N381, a Key Trimer Contact Residue in Tsr, the Escherichia coli Serine Chemoreceptor

(2011) K. K. Gosink et al.   JOURNAL OF BACTERIOLOGY

Ligand Specificity Determined by Differentially Arranged Common Ligand-binding Residues in Bacterial Amino Acid Chemoreceptors Tsr and Tar

(2011) Hirotaka Tajima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Footprinting in a Complex Milieu: Identifying the Interaction Surfaces of the Chemotaxis Adaptor Protein CheW

(2011) Eric S. Underbakke et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional and structural effects of seven-residue deletions on the coiled-coil cytoplasmic domain of a chemoreceptor

(2011) Diego A. Massazza et al.   MOLECULAR MICROBIOLOGY

Not too loose, not too tight - just right. Biphasic control of the Tsr HAMP domain

(2011) Michael D. Manson   MOLECULAR MICROBIOLOGY

Activated chemoreceptor arrays remain intact and hexagonally packed

(2011) Ariane Briegel et al.   MOLECULAR MICROBIOLOGY

Biphasic control logic of HAMP domain signalling in the Escherichia coli serine chemoreceptor

(2011) Qin Zhou et al.   MOLECULAR MICROBIOLOGY

Adapt locally and act globally: strategy to maintain high chemoreceptor sensitivity in complex environments

(2011) G. Lan et al.   Molecular Systems Biology

Signal processing in complex chemotaxis pathways

(2011) Steven L. Porter et al.   NATURE REVIEWS MICROBIOLOGY

Core unit of chemotaxis signaling complexes

(2011) M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct evidence that the carboxyl-terminal sequence of a bacterial chemoreceptor is an unstructured linker and enzyme tether

(2011) Nicholas L. Bartelli et al.   PROTEIN SCIENCE

The Mechanisms of HAMP-Mediated Signaling in Transmembrane Receptors

(2011) Hedda U. Ferris et al.   STRUCTURE

Signaling Mechanisms of HAMP Domains in Chemoreceptors and Sensor Kinases

(2010) John S. Parkinson   Annual Review of Microbiology

Cross-Linking Evidence for Motional Constraints within Chemoreceptor Trimers of Dimers

(2010) Diego A. Massazza et al.   BIOCHEMISTRY

Bacterial chemoreceptors: providing enhanced features to two-component signaling

(2010) Gerald L Hazelbauer et al.   CURRENT OPINION IN MICROBIOLOGY

Differences in signalling by directly and indirectly binding ligands in bacterial chemotaxis

(2010) Silke Neumann et al.   EMBO JOURNAL

Spatial organization in bacterial chemotaxis

(2010) Victor Sourjik et al.   EMBO JOURNAL

Diversity at its best: bacterial taxis

(2010) Tino Krell et al.   ENVIRONMENTAL MICROBIOLOGY

Sensing of environmental signals: classification of chemoreceptors according to the size of their ligand binding regions

(2010) Jesús Lacal et al.   ENVIRONMENTAL MICROBIOLOGY

Repellent Taxis in Response to Nickel Ion Requires neither Ni2+ Transport nor the Periplasmic NikA Binding Protein

(2010) D. L. Englert et al.   JOURNAL OF BACTERIOLOGY

Mutational Analysis of the Transmembrane Helix 2-HAMP Domain Connection in the Escherichia coli Aspartate Chemoreceptor Tar

(2010) G. A. Wright et al.   JOURNAL OF BACTERIOLOGY

Chemotaxis to the Quorum-Sensing Signal AI-2 Requires the Tsr Chemoreceptor and the Periplasmic LsrB AI-2-Binding Protein

(2010) M. Hegde et al.   JOURNAL OF BACTERIOLOGY

Identification of a Chemoreceptor for Tricarboxylic Acid Cycle Intermediates

(2010) Jesús Lacal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemotaxis kinase CheA is activated by three neighbouring chemoreceptor dimers as effectively as by receptor clusters

(2010) Mingshan Li et al.   MOLECULAR MICROBIOLOGY

Disruption of chemoreceptor signalling arrays by high levels of CheW, the receptor-kinase coupling protein

(2010) Marcos J. Cardozo et al.   MOLECULAR MICROBIOLOGY

“Frozen” dynamic dimer model for transmembrane signaling in bacterial chemotaxis receptors

(2010) Sung-Hou Kim   PROTEIN SCIENCE

Structure of Concatenated HAMP Domains Provides a Mechanism for Signal Transduction

(2010) Michael V. Airola et al.   STRUCTURE

Structure-Based Design of a Periplasmic Binding Protein Antagonist that Prevents Domain Closure

(2009) M. Jack Borrok et al.   ACS Chemical Biology

The Structure of a Soluble Chemoreceptor Suggests a Mechanism for Propagating Conformational Signals†‡

(2009) Abiola M. Pollard et al.   BIOCHEMISTRY

Engineered Socket Study of Signaling through a Four-Helix Bundle: Evidence for a Yin−Yang Mechanism in the Kinase Control Module of the Aspartate Receptor

(2009) Kalin E. Swain et al.   BIOCHEMISTRY

Mutational analyses of HAMP helices suggest a dynamic bundle model of input-output signalling in chemoreceptors

(2009) Qin Zhou et al.   MOLECULAR MICROBIOLOGY

Engineered single- and multi-cell chemotaxis pathways in E. coli

(2009) Shalom D Goldberg et al.   Molecular Systems Biology

The Piston Rises Again

(2009) Joseph J. Falke et al.   STRUCTURE

Chemical Probes of Bacterial Signal Transduction Reveal That Repellents Stabilize and Attractants Destabilize the Chemoreceptor Array

(2008) M. Jack Borrok et al.   ACS Chemical Biology

Salt-driven Equilibrium between Two Conformations in the HAMP Domain fromNatronomonas pharaonis

(2008) Meike Doebber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Evidence for Coupling between Bacterial Chemoreceptors

(2008) Ady Vaknin et al.   JOURNAL OF MOLECULAR BIOLOGY

Bacterial chemoreceptors: high-performance signaling in networked arrays

(2008) Gerald L. Hazelbauer et al.   TRENDS IN BIOCHEMICAL SCIENCES