Different pathways of molecular pathophysiology underlie cognitive and motor tauopathy phenotypes in transgenic models for Alzheimer’s disease and frontotemporal lobar degeneration

Alzheimer disease therapeutics: Focus on the disease and not just plaques and tangles

(2014) Khalid Iqbal et al.   BIOCHEMICAL PHARMACOLOGY

Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies

(2014) David W. Sanders et al.   NEURON

Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice

(2014) Tomohiro Onishi et al.   NEUROSCIENCE RESEARCH

Tau-aggregation inhibitor therapy for Alzheimer's disease

(2013) Claude M. Wischik et al.   BIOCHEMICAL PHARMACOLOGY

Age-dependent changes in hippocampal synaptic transmission and plasticity in the PLB1Triple Alzheimer mouse

(2013) David J. Koss et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Spatial learning impairments in PLB1Triple knock-in Alzheimer mice are task-specific and age-dependent

(2013) D. Ryan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy

(2013) M. Iba et al.   JOURNAL OF NEUROSCIENCE

Brain homogenates from human tauopathies induce tau inclusions in mouse brain

(2013) Florence Clavaguera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

(2012) Alix de Calignon et al.   NEURON

Trans-Synaptic Spread of Tau Pathology In Vivo

(2012) Li Liu et al.   PLoS One

Truncation of tau at E391 Promotes Early Pathologic Changes in Transgenic Mice

(2011) Pamela J. McMillan et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Chronic Stress Exacerbates Tau Pathology, Neurodegeneration, and Cognitive Performance through a Corticotropin-Releasing Factor Receptor-Dependent Mechanism in a Transgenic Mouse Model of Tauopathy

(2011) J. C. Carroll et al.   JOURNAL OF NEUROSCIENCE

Blast Exposure in Rats with Body Shielding Is Characterized Primarily by Diffuse Axonal Injury

(2011) Robert H. Garman et al.   JOURNAL OF NEUROTRAUMA

Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model

(2010) David E. Hurtado et al.   AMERICAN JOURNAL OF PATHOLOGY

Early behavioural markers of disease in P301S tau transgenic mice

(2009) Maria Luisa Scattoni et al.   BEHAVIOURAL BRAIN RESEARCH

Cortical and Hippocampal Neurons from Truncated Tau Transgenic Rat Express Multiple Markers of Neurodegeneration

(2009) Peter Filipcik et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Propagation of Tau Misfolding from the Outside to the Inside of a Cell

(2009) Bess Frost et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Association Between Rough Endoplasmic Reticulum Membranes and Mitochondria in Transgenic Mice That Express P301L Tau

(2009) Sébastien Perreault et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Transmission and spreading of tauopathy in transgenic mouse brain

(2009) Florence Clavaguera et al.   NATURE CELL BIOLOGY

Truncated tau expression levels determine life span of a rat model of tauopathy without causing neuronal loss or correlating with terminal neurofibrillary tangle load

(2008) Peter Koson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Memory loss in Alzheimer’s disease: implications for development of therapeutics

(2008) Carl A Gold et al.   Expert Review of Neurotherapeutics

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

(2008) L. M. Ittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knock-out and transgenic mouse models of tauopathies

(2007) Franziska Denk et al.   NEUROBIOLOGY OF AGING