Regulation of male sex determination: genital ridge formation and Sry activation in mice

Transient Neuroprotection by SRY Upregulation in Dopamine Cells Following Injury in Males

(2014) Daniel P. Czech et al.   ENDOCRINOLOGY

Regulation of Sex Determination in Mice by a Non-coding Genomic Region

(2014) V. A. Arboleda et al.   GENETICS

Homeoproteins Six1 and Six4 Regulate Male Sex Determination and Mouse Gonadal Development

(2013) Yuka Fujimoto et al.   DEVELOPMENTAL CELL

Just how conserved is vertebrate sex determination?

(2013) Andrew Cutting et al.   DEVELOPMENTAL DYNAMICS

Disorders of sex development: new genes, new concepts

(2013) Makoto Ono et al.   Nature Reviews Endocrinology

Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction in the Mouse

(2013) Yasuhiro Yamauchi et al.   SCIENCE

Epigenetic Regulation of Mouse Sex Determination by the Histone Demethylase Jmjd1a

(2013) S. Kuroki et al.   SCIENCE

Insulin and IGF1 Receptors Are Essential for XX and XY Gonadal Differentiation and Adrenal Development in Mice

(2013) Jean-Luc Pitetti et al.   PLoS Genetics

Fine Time Course Expression Analysis Identifies Cascades of Activation and Repression and Maps a Putative Regulator of Mammalian Sex Determination

(2013) Steven C. Munger et al.   PLoS Genetics

Gata4 Is Required for Formation of the Genital Ridge in Mice

(2013) Yueh-Chiang Hu et al.   PLoS Genetics

Direct Reprogramming of Fibroblasts into Embryonic Sertoli-like Cells by Defined Factors

(2012) Yosef Buganim et al.   Cell Stem Cell

Mammalian sex determination—insights from humans and mice

(2012) Stefanie Eggers et al.   CHROMOSOME RESEARCH

GADD45G Functions in Male Sex Determination by Promoting p38 Signaling and Sry Expression

(2012) Mathias S. Gierl et al.   DEVELOPMENTAL CELL

Gadd45γ and Map3k4 Interactions Regulate Mouse Testis Determination via p38 MAPK-Mediated Control of Sry Expression

(2012) Nick Warr et al.   DEVELOPMENTAL CELL

Early gonadogenesis in mammals: Significance of long and narrow gonadal structure

(2012) Kyoko Harikae et al.   DEVELOPMENTAL DYNAMICS

Excess DAX1 Leads to XY Ovotesticular Disorder of Sex Development (DSD) in Mice by Inhibiting Steroidogenic Factor-1 (SF1) Activation of the Testis Enhancer ofSRY-box-9(Sox9)

(2012) Louisa M. Ludbrook et al.   ENDOCRINOLOGY

The Cbln family of proteins interact with multiple signaling pathways

(2012) Peng Wei et al.   JOURNAL OF NEUROCHEMISTRY

The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells

(2012) Stefanie Seisenberger et al.   MOLECULAR CELL

Global Genome Analysis of the Downstream Binding Targets of Testis Determining Factor SRY and SOX9

(2012) Ramji K. Bhandari et al.   PLoS One

Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice

(2012) K. Hayashi et al.   SCIENCE

How to Make a Gonad: Cellular Mechanisms Governing Formation of the Testes and Ovaries

(2012) E.K. Ungewitter et al.   Sexual Development

Genetic Control of Testis Development

(2012) R. Sekido et al.   Sexual Development

Sex Reversal in C57BL/6J XY Mice Caused by Increased Expression of Ovarian Genes and Insufficient Activation of the Testis Determining Pathway

(2012) Stephanie M. Correa et al.   PLoS Genetics

SRY Directly Regulates the Neurotrophin 3 Promoter During Male Sex Determination and Testis Development in Rats1

(2011) Tracy M. Clement et al.   BIOLOGY OF REPRODUCTION

Temporal Differences in Granulosa Cell Specification in the Ovary Reflect Distinct Follicle Fates in Mice1

(2011) Lindsey Mork et al.   BIOLOGY OF REPRODUCTION

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

(2011) Katsuhiko Hayashi et al.   CELL

Two distinct origins for Leydig cell progenitors in the fetal testis

(2011) Tony DeFalco et al.   DEVELOPMENTAL BIOLOGY

Wnt Signaling in Ovarian Development Inhibits Sf1 Activation ofSox9via theTescoEnhancer

(2011) Pascal Bernard et al.   ENDOCRINOLOGY

Identification of an Enhancer in theAd4BP/SF-1Gene Specific for Fetal Leydig Cells

(2011) Yuichi Shima et al.   ENDOCRINOLOGY

Cbx2, a Polycomb Group Gene, Is Required forSryGene Expression in Mice

(2011) Yuko Katoh-Fukui et al.   ENDOCRINOLOGY

Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice

(2011) Kenichi Kashimada et al.   FASEB JOURNAL

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome

(2011) Stefan Bagheri-Fam et al.   HUMAN MOLECULAR GENETICS

DMRT1 prevents female reprogramming in the postnatal mammalian testis

(2011) Clinton K. Matson et al.   NATURE

In vitro production of functional sperm in cultured neonatal mouse testes

(2011) Takuya Sato et al.   NATURE

Basic Helix-Loop-Helix Transcription Factor TCF21 Is a Downstream Target of the Male Sex Determining Gene SRY

(2011) Ramji K. Bhandari et al.   PLoS One

Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells

(2011) M. E. Gill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FGF9 Suppresses Meiosis and Promotes Male Germ Cell Fate in Mice

(2010) Josephine Bowles et al.   DEVELOPMENTAL CELL

Abnormal Epithelial Cell Polarity and Ectopic Epidermal Growth Factor Receptor (EGFR) Expression Induced in Emx2 KO Embryonic Gonads

(2010) Masatomo Kusaka et al.   ENDOCRINOLOGY

Identification of SOX3 as an XX male sex reversal gene in mice and humans

(2010) Edwina Sutton et al.   JOURNAL OF CLINICAL INVESTIGATION

Activin A, a product of fetal Leydig cells, is a unique paracrine regulator of Sertoli cell proliferation and fetal testis cord expansion

(2010) D. R. Archambeault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ovaries and Female Phenotype in a Girl with 46,XY Karyotype and Mutations in the CBX2 Gene

(2009) Anna Biason-Lauber et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Cerebellin 4 Precursor Gene Is a Direct Target of SRY and SOX9 in Mice1

(2009) Stephen T. Bradford et al.   BIOLOGY OF REPRODUCTION

Somatic Sex Reprogramming of Adult Ovaries to Testes by FOXL2 Ablation

(2009) N. Henriette Uhlenhaut et al.   CELL

Self-renewing epiblast stem cells exhibit continual delineation of germ cells with epigenetic reprogramming in vitro

(2009) K. Hayashi et al.   DEVELOPMENT

Evidence for crucial role of hindgut expansion in directing proper migration of primordial germ cells in mouse early embryogenesis

(2009) Kenshiro Hara et al.   DEVELOPMENTAL BIOLOGY

The Mammalian Ovary from Genesis to Revelation

(2009) Mark A. Edson et al.   ENDOCRINE REVIEWS

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

(2009) S. C. Munger et al.   GENES & DEVELOPMENT

Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development

(2009) Juan Carlos Polanco et al.   HUMAN MOLECULAR GENETICS

A cell-autonomous role for WT1 in regulating Sry in vivo

(2009) S. T. Bradford et al.   HUMAN MOLECULAR GENETICS

Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

(2009) Erica L. McCoy et al.   JOURNAL OF CLINICAL INVESTIGATION

Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice

(2009) Dagmar Wilhelm et al.   MECHANISMS OF DEVELOPMENT

Molecular aspects of steroidogenic factor 1 (SF-1)

(2009) Erling A. Hoivik et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Loss of Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) Reveals a Requirement for MAPK Signalling in Mouse Sex Determination

(2009) Debora Bogani et al.   PLOS BIOLOGY

A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation

(2008) Yoko Miyamoto et al.   BMC MOLECULAR BIOLOGY

The sine oculis homeobox (SIX) family of transcription factors as regulators of development and disease

(2008) J. P. Kumar   CELLULAR AND MOLECULAR LIFE SCIENCES

A critical time window of Sry action in gonadal sex determination in mice

(2008) R. Hiramatsu et al.   DEVELOPMENT

Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8

(2008) Francisco Barrionuevo et al.   DEVELOPMENTAL BIOLOGY

Endothelial cell migration directs testis cord formation

(2008) Alexander N. Combes et al.   DEVELOPMENTAL BIOLOGY

R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling

(2008) Kazuma Tomizuka et al.   HUMAN MOLECULAR GENETICS

Stabilization of β-catenin in XY gonads causes male-to-female sex-reversal

(2008) Danielle M. Maatouk et al.   HUMAN MOLECULAR GENETICS

Activation of  -catenin signaling by Rspo1 controls differentiation of the mammalian ovary

(2008) A.-A. Chassot et al.   HUMAN MOLECULAR GENETICS

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

(2008) Ryohei Sekido et al.   NATURE

A W-linked DM-domain gene, DM-W, participates in primary ovary development in Xenopus laevis

(2008) S. Yoshimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germ Cell-Intrinsic and -Extrinsic Factors Govern Meiotic Initiation in Mouse Embryos

(2008) Y. Lin et al.   SCIENCE

Steroidogenic Factor-1 (SF-1, Ad4BP, NR5A1) and Disorders of Testis Development

(2008) L. Lin et al.   Sexual Development

Peritubular Myoid Cells Are Not the Migrating Population Required for Testis Cord Formation in the XY Gonad

(2008) J. Cool et al.   Sexual Development

Loss of Fgfr2 leads to partial XY sex reversal

(2007) Stefan Bagheri-Fam et al.   DEVELOPMENTAL BIOLOGY