Prevention of cisplatin-induced ototoxicity by the inhibition of gap junctional intercellular communication in auditory cells

Role of the Copper Transporter, CTR1, in Platinum-Induced Ototoxicity

(2013) S. S. More et al.   JOURNAL OF NEUROSCIENCE

Gap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure

(2012) Suraj J Patel et al.   NATURE BIOTECHNOLOGY

Gap junctions propagate opposite effects in normal and tumor testicular cells in response to cisplatin

(2011) Xiaoting Hong et al.   CANCER LETTERS

Connexin-26 Is a Key Factor Mediating Gemcitabine Bystander Effect

(2011) L. Garcia-Rodriguez et al.   MOLECULAR CANCER THERAPEUTICS

Cisplatin regulates the MAPK kinase pathway to induce increased expression of DNA repair gene ERCC1 and increase melanoma chemoresistance

(2011) W Li et al.   ONCOGENE

Pharmacogenomics of cisplatin-induced ototoxicity

(2011) Debashree Mukherjea et al.   PHARMACOGENOMICS

Organic Cation Transporter 2 Mediates Cisplatin-Induced Oto- and Nephrotoxicity and Is a Target for Protective Interventions

(2010) Giuliano Ciarimboli et al.   AMERICAN JOURNAL OF PATHOLOGY

Transtympanic Administration of Short Interfering (si)RNA for the NOX3 Isoform of NADPH Oxidase Protects Against Cisplatin-Induced Hearing Loss in the Rat

(2010) Debashree Mukherjea et al.   ANTIOXIDANTS & REDOX SIGNALING

Disruption of gap junctions attenuates aminoglycoside-elicited renal tubular cell injury

(2010) Jian Yao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Epicatechin protects the auditory organ by attenuating cisplatin-induced ototoxicity through inhibition of ERK

(2010) J.S. Lee et al.   TOXICOLOGY LETTERS

Connexin-related signaling in cell death: to live or let die?

(2009) E Decrock et al.   CELL DEATH AND DIFFERENTIATION

Potassium Ion Movement in the Inner Ear: Insights from Genetic Disease and Mouse Models

(2009) Anselm A. Zdebik et al.   PHYSIOLOGY

Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies

(2009) Leonard P Rybak et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Hemichannel-Mediated Inositol 1,4,5-Trisphosphate (IP3) Release in the Cochlea: A Novel Mechanism of IP3Intercellular Signaling

(2008) David G. Gossman et al.   CELL COMMUNICATION AND ADHESION

Luteolin Suppresses Cisplatin-Induced Apoptosis in Auditory Cells: Possible Mediation Through Induction of Heme Oxygenase-1 Expression

(2008) Byung-Min Choi et al.   JOURNAL OF MEDICINAL FOOD

Damage-Induced Activation of ERK1/2 in Cochlear Supporting Cells Is a Hair Cell Death-Promoting Signal That Depends on Extracellular ATP and Calcium

(2008) M. Lahne et al.   JOURNAL OF NEUROSCIENCE

Gap Junction Mediated Intercellular Metabolite Transfer in the Cochlea Is Compromised in Connexin30 Null Mice

(2008) Qing Chang et al.   PLoS One

Bcl-2 Protein Family Members: Versatile Regulators of Calcium Signaling in Cell Survival and Apoptosis

(2007) Yiping Rong et al.   Annual Review of Physiology