Proteasome assembly

Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines

(2014) Denise Niewerth et al.   Journal of Hematology & Oncology

The Intrinsically Disordered Sem1 Protein Functions as a Molecular Tether during Proteasome Lid Biogenesis

(2014) Robert J. Tomko et al.   MOLECULAR CELL

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

(2014) G. R. Pathare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture and assembly of the archaeal Cdc48*20S proteasome

(2014) D. Barthelme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Proteasome Formation Controlled by an Assembly Chaperone Nas2

(2014) Tadashi Satoh et al.   STRUCTURE

Proteasome dynamics

(2013) Cordula Enenkel   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis

(2013) Min-Xian Qian et al.   CELL

Reconfiguration of the proteasome during chaperone-mediated assembly

(2013) Soyeon Park et al.   NATURE

Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase

(2013) Robyn Beckwith et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An Archaeal Homolog of Proteasome Assembly Factor Functions as a Proteasome Activator

(2013) Kentaro Kumoi et al.   PLoS One

Integrity of the Saccharomyces cerevisiae Rpn11 Protein Is Critical for Formation of Proteasome Storage Granules (PSG) and Survival in Stationary Phase

(2013) Rémy Saunier et al.   PLoS One

Formation of an Intricate Helical Bundle Dictates the Assembly of the 26S Proteasome Lid

(2013) Eric Estrin et al.   STRUCTURE

Involvement of Bag6 and the TRC pathway in proteasome assembly

(2013) Takashi Akahane et al.   Nature Communications

BIOCHEMICAL AND BIOPHYSICAL CHARACTERIZATION OF RECOMBINANT YEAST PROTEASOME MATURATION FACTOR UMP1

(2013) Bebiana Sá-Moura et al.   Computational and Structural Biotechnology Journal

The proteasome: molecular machinery and pathophysiological roles

(2012) Keiji Tanaka et al.   BIOLOGICAL CHEMISTRY

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

(2012) Eva M. Huber et al.   CELL

Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells

(2012) Samuel Marguerat et al.   CELL

Rpn1 and Rpn2 Coordinate Ubiquitin Processing Factors at Proteasome

(2012) Rina Rosenzweig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Specific Recognition of Rpt1p, an ATPase Subunit of 26 S Proteasome, by Proteasome-dedicated Chaperone Hsm3p

(2012) Kenji Takagi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spg5 Protein Regulates the Proteasome in Quiescence

(2012) John Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a Proteasome Pba1-Pba2 Complex

(2012) Beth M. Stadtmueller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Model of the Human 26S Proteasome

(2012) Paula C.A. da Fonseca et al.   MOLECULAR CELL

Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy

(2012) E. Sakata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly

(2012) M.-B. Barrault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of the 26S Proteasome Subunit Rpn2 Reveals Its PC Repeat Domain as a Closed Toroid of Two Concentric α-Helical Rings

(2012) Jun He et al.   STRUCTURE

AAA+ Proteases: ATP-Fueled Machines of Protein Destruction

(2011) Robert T. Sauer et al.   Annual Review of Biochemistry

Proteasomal AAA-ATPases: Structure and function

(2011) Shoshana Bar-Nun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Kinetic Asymmetry of Subunit Exchange of Homooligomeric Protein as Revealed by Deuteration-Assisted Small-Angle Neutron Scattering

(2011) Masaaki Sugiyama et al.   BIOPHYSICAL JOURNAL

The role of the proteasome in the generation of MHC class I ligands and immune responses

(2011) E. J. A. M. Sijts et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Blm10 Protein Promotes Proteasomal Substrate Turnover by an Active Gating Mechanism

(2011) Thomas Dange et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Defects in the Regulatory Particle-Core Particle Interface of the Proteasome Induce a Novel Proteasome Stress Response

(2011) Soyeon Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Not4 E3 Ligase Contributes to Proteasome Assembly and Functional Integrity in Part through Ecm29

(2011) O. O. Panasenko et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear import of an intact preassembled proteasome particle

(2011) Anca F. Savulescu et al.   MOLECULAR BIOLOGY OF THE CELL

Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10

(2011) Antonio Diaz Lopez et al.   MOLECULAR BIOLOGY OF THE CELL

Proteasome Activators

(2011) Beth M. Stadtmueller et al.   MOLECULAR CELL

Incorporation of the Rpn12 Subunit Couples Completion of Proteasome Regulatory Particle Lid Assembly to Lid-Base Joining

(2011) Robert J. Tomko et al.   MOLECULAR CELL

An asymmetric interface between the regulatory and core particles of the proteasome

(2011) Geng Tian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding

(2011) Andrew R Kusmierczyk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together

(2011) G. R. Pathare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity

(2011) X. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissection of the assembly pathway of the proteasome lid in Saccharomyces cerevisiae

(2010) Keisuke Fukunaga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reduced Immunoproteasome Formation and Accumulation of Immunoproteasomal Precursors in the Brains of Lymphocytic Choriomeningitis Virus-Infected Mice

(2010) M. Kremer et al.   JOURNAL OF IMMUNOLOGY

ATP-Dependent Steps in the Binding of Ubiquitin Conjugates to the 26S Proteasome that Commit to Degradation

(2010) Andreas Peth et al.   MOLECULAR CELL

Ecm29 Fulfils Quality Control Functions in Proteasome Assembly

(2010) Andrea Lehmann et al.   MOLECULAR CELL

Heterohexameric Ring Arrangement of the Eukaryotic Proteasomal ATPases: Implications for Proteasome Structure and Assembly

(2010) Robert J. Tomko et al.   MOLECULAR CELL

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

(2010) B. Guillaume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the 26S Proteasome Complex During Oxidative Stress

(2010) X. Wang et al.   Science Signaling

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

Multiple Proteasome-Interacting Proteins Assist the Assembly of the Yeast 19S Regulatory Particle

(2009) Yasushi Saeki et al.   CELL

Getting to First Base in Proteasome Assembly

(2009) Henrike C. Besche et al.   CELL

Multiple Assembly Chaperones Govern Biogenesis of the Proteasome Regulatory Particle Base

(2009) Minoru Funakoshi et al.   CELL

Assembly Pathway of the Mammalian Proteasome Base Subcomplex Is Mediated by Multiple Specific Chaperones

(2009) Takeumi Kaneko et al.   CELL

Controlled destruction: AAA+ ATPases in protein degradation from bacteria to eukaryotes

(2009) Frank Striebel et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Duplicated proteasome subunit genes in Drosophila and their roles in spermatogenesis

(2009) J M Belote et al.   HEREDITY

Subcomplexes of PA700, the 19 S Regulator of the 26 S Proteasome, Reveal Relative Roles of AAA Subunits in 26 S Proteasome Assembly and Activation and ATPase Activity

(2009) David Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Electron Microscopic Evidence in Support of α-Solenoid Models of Proteasomal Subunits Rpn1 and Rpn2

(2009) Grégory Effantin et al.   JOURNAL OF MOLECULAR BIOLOGY

The 20S Proteasome as an Assembly Platform for the 19S Regulatory Complex

(2009) Klavs B. Hendil et al.   JOURNAL OF MOLECULAR BIOLOGY

Hsm3/S5b Joins the Ranks of 26S Proteasome Assembly Chaperones

(2009) Daniela Gödderz et al.   MOLECULAR CELL

Hsm3/S5b Participates in the Assembly Pathway of the 19S Regulatory Particle of the Proteasome

(2009) Benoît Le Tallec et al.   MOLECULAR CELL

Chaperone-mediated pathway of proteasome regulatory particle assembly

(2009) Jeroen Roelofs et al.   NATURE

Hexameric assembly of the proteasomal ATPases is templated through their C termini

(2009) Soyeon Park et al.   NATURE

Molecular mechanisms of proteasome assembly

(2009) Shigeo Murata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chronic ethanol feeding affects proteasome-interacting proteins

(2009) Marie-Pierre Bousquet-Dubouch et al.   PROTEOMICS

Mammalian 26S Proteasomes Remain Intact during Protein Degradation

(2008) Franziska Kriegenburg et al.   CELL

Thymoproteasome: probable role in generating positively selecting peptides

(2008) Shigeo Murata et al.   CURRENT OPINION IN IMMUNOLOGY

Dissecting β-ring assembly pathway of the mammalian 20S proteasome

(2008) Yuko Hirano et al.   EMBO JOURNAL

Blm10 binds to pre-activated proteasome core particles with open gate conformation

(2008) Andrea Lehmann et al.   EMBO REPORTS

Differential Roles of the COOH Termini of AAA Subunits of PA700 (19 S Regulator) in Asymmetric Assembly and Activation of the 26 S Proteasome

(2008) Thomas G. Gillette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes

(2008) Hideki Yashiroda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A multimeric assembly factor controls the formation of alternative 20S proteasomes

(2008) Andrew R Kusmierczyk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The AAA+ superfamily of functionally diverse proteins

(2008) Jamie Snider et al.   GENOME BIOLOGY