The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE)

F-box protein substrate recognition

(2013) Bill B. Chen et al.   CELL CYCLE

The Ubiquitin Ligase Praja1 Reduces NRAGE Expression and Inhibits Neuronal Differentiation of PC12 Cells

(2013) Jan Teuber et al.   PLoS One

Linear ubiquitination: a newly discovered regulator of cell signalling

(2013) Eva Rieser et al.   TRENDS IN BIOCHEMICAL SCIENCES

F-Box Only Protein 7 Gene in Parkinsonian-Pyramidal Disease

(2013) Hao Deng et al.   JAMA Neurology

Identification of F-box only protein 7 as a negative regulator of NF-kappaB signalling

(2012) Hendrik J. Kuiken et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Ubiquitin chain conformation regulates recognition and activity of interacting proteins

(2012) Yu Ye et al.   NATURE

Pleiotropic effects of the bone morphogenetic proteins on development of the enteric nervous system

(2011) Alcmène Chalazonitis et al.   Developmental Neurobiology

A Competitive Binding Mechanism between Skp1 and Exportin 1 (CRM1) Controls the Localization of a Subset of F-box Proteins

(2011) David E. Nelson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Nuclear Activity of the FBXO7 Protein in Patients with Parkinsonian-Pyramidal Syndrome (PARK15)

(2011) Tianna Zhao et al.   PLoS One

A Small Peptide Modeled after the NRAGE Repeat Domain Inhibits XIAP-TAB1-TAK1 Signaling for NF-κB Activation and Apoptosis in P19 Cells

(2011) Jennifer A. Rochira et al.   PLoS One

A role for NRAGE in NF-κB activation through the non-canonical BMP pathway

(2010) Nicholas Matluk et al.   BMC BIOLOGY

Melanoma-associated antigen genes – An update

(2010) Meixiang Sang et al.   CANCER LETTERS

Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations

(2010) Coro Paisán-Ruiz et al.   MOVEMENT DISORDERS

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

The emerging complexity of protein ubiquitination

(2009) David Komander   BIOCHEMICAL SOCIETY TRANSACTIONS

BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways

(2009) Y. Morikawa et al.   DEVELOPMENT

Genome-wide Linkage Analysis of a Parkinsonian-Pyramidal Syndrome Pedigree by 500 K SNP Arrays

(2008) Seyedmehdi Shojaee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Characterization of Polyubiquitin Chain Structure by Middle-down Mass Spectrometry

(2008) Ping Xu et al.   ANALYTICAL CHEMISTRY

NRAGE, a p75NTR adaptor protein, is required for developmental apoptosis in vivo

(2008) M J M Bertrand et al.   CELL DEATH AND DIFFERENTIATION

Structure of a Conserved Dimerization Domain within the F-box Protein Fbxo7 and the PI31 Proteasome Inhibitor

(2008) Rebecca Kirk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

(2008) A. D. Fonzo et al.   NEUROLOGY