Protective role of hemeoxygenase-1 in gastrointestinal diseases

Immune cells and immune-based therapy in pancreatitis

(2014) Jing Xue et al.   IMMUNOLOGIC RESEARCH

Heme Oxygenase-1 Gene Promoter Polymorphism Is Associated With the Development of Necrotizing Acute Pancreatitis

(2014) Aiste Gulla et al.   PANCREAS

Remote Ischemic Preconditioning Protects against Liver Ischemia-Reperfusion Injury via Heme Oxygenase-1-Induced Autophagy

(2014) Yun Wang et al.   PLoS One

Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells

(2014) B Wegiel et al.   Cell Death & Disease

Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model

(2013) Stephanie Schulz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Induction of heme oxygenase-1 protects mouse liver from apoptotic ischemia/reperfusion injury

(2013) Z. Ben-Ari et al.   APOPTOSIS

Role of Immune Cells and Immune-Based Therapies in Pancreatitis and Pancreatic Ductal Adenocarcinoma

(2013) Lei Zheng et al.   GASTROENTEROLOGY

The Epidemiology of Pancreatitis and Pancreatic Cancer

(2013) Dhiraj Yadav et al.   GASTROENTEROLOGY

BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice

(2013) Akihito Harusato et al.   INFLAMMATORY BOWEL DISEASES

Carbon monoxide–based therapy ameliorates acute pancreatitis via TLR4 inhibition

(2013) Jing Xue et al.   JOURNAL OF CLINICAL INVESTIGATION

Carbon monoxide: Anticoagulant or procoagulant?

(2013) Vance G. Nielsen et al.   THROMBOSIS RESEARCH

Aryl Hydrocarbon Receptor Regulates Pancreatic IL-22 Production and Protects Mice From Acute Pancreatitis

(2012) Jing Xue et al.   GASTROENTEROLOGY

Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo

(2012) Yu-Ting Cheng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Heme Oxygenase 1–Generated Carbon Monoxide and Biliverdin Attenuate the Course of Experimental Necrotizing Pancreatitis

(2012) Philipp Nuhn et al.   PANCREAS

Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice

(2011) Evie H. Carchman et al.   HEPATOLOGY

An Anti-Inflammatory Role for Carbon Monoxide and Heme Oxygenase-1 in Chronic Th2-Mediated Murine Colitis

(2011) S. Z. Sheikh et al.   JOURNAL OF IMMUNOLOGY

Heme Oxygenase-1 Is Protective Against Nonsteroidal Anti-inflammatory Drug–induced Gastric Ulcers

(2011) Aliye Uc et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine

(2010) Cleber Rosito Pinto Kruel et al.   Acta Cirurgica Brasileira

Heme oxygenase-1 is induced in peripheral blood mononuclear cells of patients with acute pancreatitis: a potential therapeutic target

(2010) Aida Habtezion et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

CD206-Positive M2 Macrophages That Express Heme Oxygenase-1 Protect Against Diabetic Gastroparesis in Mice

(2010) Kyoung Moo Choi et al.   GASTROENTEROLOGY

Panhematin provides a therapeutic benefit in experimental pancreatitis

(2010) A. Habtezion et al.   GUT

Hemin Exerts Multiple Protective Mechanisms and Attenuates Dextran Sulfate Sodium–induced Colitis

(2010) Wenwei Zhong et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Human Heme Oxygenase-1 Deficiency Presenting With Hemolysis, Nephritis, and Asplenia

(2010) Nita Radhakrishnan et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling

(2010) C. I. Schwer et al.   MOLECULAR PHARMACOLOGY

The protective role of HO-1 and its generated products (CO, bilirubin, and Fe) in ethanol-induced human hepatocyte damage

(2009) Ping Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ischemic preconditioning of small bowel mitigates the late phase of reperfusion injury: heme oxygenase mediates cytoprotection

(2009) Ismail H. Mallick et al.   AMERICAN JOURNAL OF SURGERY

Eupatilin with Heme Oxygenase-1-Inducing Ability Protects Cultured Feline Esophageal Epithelial Cells from Cell Damage Caused by Indomethacin

(2009) Hyun Ju Song et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

First-in-Human Study Demonstrating Pharmacological Activation of Heme Oxygenase-1 in Humans

(2009) A E Bharucha et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Effects of carbon monoxide releasing molecule-liberated CO on severe acute pancreatitis in rats

(2009) Ping Chen et al.   CYTOKINE

Tolerogenic dendritic cells actively inhibit T cells through heme oxygenase-1 in rodents and in nonhuman primates

(2009) A. Moreau et al.   FASEB JOURNAL

Enhanced ROS production and redox signaling with combined arsenite and UVA exposure: Contribution of NADPH oxidase

(2009) Karen L. Cooper et al.   FREE RADICAL BIOLOGY AND MEDICINE

Taurine Chloramine Activates Nrf2, Increases HO-1 Expression and Protects Cells from Death Caused by Hydrogen Peroxide

(2009) Jin Sun Jang et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Pleiotropic Effects of Proton Pump Inhibitors Guest Editor: Yuji Naito Prevention of NSAID-Induced Small Intestinal Mucosal Injury: Prophylactic Potential of Lansoprazole

(2009) Kazuhide Higuchi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production

(2009) Sotiria Tzima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Carbon Monoxide Inhibits TLR-Induced Dendritic Cell Immunogenicity

(2009) S. Remy et al.   JOURNAL OF IMMUNOLOGY

Polaprezinc (Zinc L-Carnosine) Is a Potent Inducer of Anti-oxidative Stress Enzyme, Heme Oxygenase (HO)-1 — a New Mechanism of Gastric Mucosal Protection

(2009) Kazuki Ueda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Lansoprazole, a Proton Pump Inhibitor, Mediates Anti-Inflammatory Effect in Gastric Mucosal Cells through the Induction of Heme Oxygenase-1 via Activation of NF-E2-Related Factor 2 and Oxidation of Kelch-Like ECH-Associating Protein 1

(2009) T. Takagi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Protective effect of sulforaphane on indomethacin-induced cytotoxicityviaheme oxygenase-1 expression in human intestinal Int 407 cells

(2009) Chi-Tai Yeh et al.   MOLECULAR NUTRITION & FOOD RESEARCH

HYPOXIA-INDUCIBLE FACTOR 1/HEME OXYGENASE 1 CASCADE AS UPSTREAM SIGNALS IN THE PROLIFE ROLE OF HEAT SHOCK PROTEIN 70 AT ROSTRAL VENTROLATERAL MEDULLA DURING EXPERIMENTAL BRAIN STEM DEATH

(2009) Alice Y.W. Chang et al.   SHOCK

Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin

(2009) Jaime Kapitulnik et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Suppression by CD4+CD25+ Regulatory T Cells Is Dependent on Expression of Heme Oxygenase-1 in Antigen-Presenting Cells

(2008) James F. George et al.   AMERICAN JOURNAL OF PATHOLOGY

Low-dose inhaled carbon monoxide attenuates the remote intestinal inflammatory response elicited by hindlimb ischemia-reperfusion

(2008) Jeffrey R. Scott et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The involvement of heme oxygenase-1 activity in the therapeutic actions of 5-aminosalicylic acid in rat colitis

(2008) Krisztina Horváth et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Heme Oxygenase-1 Protects Interstitial Cells of Cajal From Oxidative Stress and Reverses Diabetic Gastroparesis

(2008) Kyoung Moo Choi et al.   GASTROENTEROLOGY

Water-soluble CO-releasing molecules reduce the development of postoperative ileus via modulation of MAPK/HO-1 signalling and reduction of oxidative stress

(2008) O De Backer et al.   GUT

Heme Oxygenase and Carbon Monoxide: Medicinal Chemistry and Biological Effects Guest Editor: Yuji Naito Application of Heme Oxygenase-1, Carbon Monoxide and Biliverdin for the Prevention of Intestinal Ischemia/Reperfusion Injury

(2008) Atsunori Nakao et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Heme oxygenase-1–derived carbon monoxide enhances the host defense response to microbial sepsis in mice

(2008) Su Wol Chung et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased intestinal expression of heme oxygenase-1 and its localization in patients with ulcerative colitis

(2008) Tomohisa Takagi et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Heme Oxygenase-1 Inhibits the Proliferation of Pancreatic Stellate Cells by Repression of the Extracellular Signal-Regulated Kinase1/2 Pathway

(2008) C. I. Schwer et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Eupatilin Protects Gastric Epithelial Cells from Oxidative Damage and Down-Regulates Genes Responsible for the Cellular Oxidative Stress

(2008) Eun-Ju Choi et al.   PHARMACEUTICAL RESEARCH

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS

PREVENTION OF HEMORRHAGIC SHOCK-INDUCED INTESTINAL TISSUE INJURY BY GLUTAMINE VIA HEME OXYGENASE-1 INDUCTION

(2008) Kana Umeda et al.   SHOCK

The dimethylthiourea-induced attenuation of cisplatin nephrotoxicity is associated with the augmented induction of heat shock proteins

(2008) Takayuki Tsuji et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY