The ZIC gene family encodes multi-functional proteins essential for patterning and morphogenesis

An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis

(2012) Ashley E. Cast et al.   DEVELOPMENTAL BIOLOGY

Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice

(2012) Malgorzata E. Quinn et al.   HUMAN MOLECULAR GENETICS

Zinc fingers of the cerebellum (Zic): Transcription factors and co-factors

(2012) Radiya G. Ali et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Initiating head development in mouse embryos: integrating signalling and transcriptional activity

(2012) R. M. Arkell et al.   Open Biology

From VACTERL-H to heterotaxy: Variable expressivity of ZIC3-related disorders

(2011) Brian Chung et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The role of Zic family zinc finger transcription factors in the proliferation and differentiation of retinal progenitor cells

(2011) Yui Watabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis

(2011) M. C. Blank et al.   DEVELOPMENT

A role for Zic1 and Zic2 in Myf5 regulation and somite myogenesis

(2011) Hua Pan et al.   DEVELOPMENTAL BIOLOGY

Xenopus Zic3 controls notochord and organizer development through suppression of the Wnt/β-catenin signaling pathway

(2011) Takahiko J. Fujimi et al.   DEVELOPMENTAL BIOLOGY

Transcription Factor Zic2 Inhibits Wnt/β-Catenin Protein Signaling

(2011) Rasoul Pourebrahim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of BMP, FGF, Calcium Signaling, and Zic Proteins in Vertebrate Neuroectodermal Differentiation

(2011) Jun Aruga et al.   NEUROCHEMICAL RESEARCH

Identification of a Novel ZIC3 Isoform and Mutation Screening in Patients with Heterotaxy and Congenital Heart Disease

(2011) James E. J. Bedard et al.   PLoS One

Characterization of the tandem CWCH2 sequence motif: a hallmark of inter-zinc finger interactions

(2010) Minoru Hatayama et al.   BMC EVOLUTIONARY BIOLOGY

Low-complexity regions within protein sequences have position-dependent roles

(2010) Alain Coletta et al.   BMC Systems Biology

Polyalanine expansion in the ZIC3 gene leading to X-linked heterotaxy with VACTERL association: a new polyalanine disorder?

(2010) M. W. Wessels et al.   JOURNAL OF MEDICAL GENETICS

UniPROBE, update 2011: expanded content and search tools in the online database of protein-binding microarray data on protein-DNA interactions

(2010) K. Robasky et al.   NUCLEIC ACIDS RESEARCH

The Pluripotency Regulator Zic3 Is a Direct Activator of the Nanog Promoter in ESCs

(2010) Linda Shushan Lim et al.   STEM CELLS

Expression and phylogenetic analysis of the zic gene family in the evolution and development of metazoans

(2010) Michael J Layden et al.   EvoDevo

Xenopus Meis3 protein lies at a nexus downstream to Zic1 and Pax3 proteins, regulating multiple cell-fates during early nervous system development

(2009) Yoni E. Gutkovich et al.   DEVELOPMENTAL BIOLOGY

The full spectrum of holoprosencephaly-associated mutations within theZIC2gene in humans predicts loss-of-function as the predominant disease mechanism

(2009) Erich Roessler et al.   HUMAN MUTATION

EMAGE mouse embryo spatial gene expression database: 2010 update

(2009) Lorna Richardson et al.   NUCLEIC ACIDS RESEARCH

BMP inhibition initiates neural induction via FGF signaling and Zic genes

(2009) L. Marchal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding synergy in genetic interactions

(2009) José Manuel Pérez-Pérez et al.   TRENDS IN GENETICS

Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms

(2008) C. Garcia-Frigola et al.   DEVELOPMENT

Zic2 is expressed in pluripotent cells in the blastocyst and adult brain expression overlaps with makers of neurogenesis

(2008) Lucia Brown et al.   GENE EXPRESSION PATTERNS

Functional and structural basis of the nuclear localization signal in the ZIC3 zinc finger domain

(2008) Minoru Hatayama et al.   HUMAN MOLECULAR GENETICS

Zic2 -associated holoprosencephaly is caused by a transient defect in the organizer region during gastrulation

(2008) Nicholas Warr et al.   HUMAN MOLECULAR GENETICS

Zic2 Regulates Retinal Ganglion Cell Axon Avoidance of ephrinB2 through Inducing Expression of the Guidance Receptor EphB1

(2008) R. Lee et al.   JOURNAL OF NEUROSCIENCE

Zic Deficiency in the Cortical Marginal Zone and Meninges Results in Cortical Lamination Defects Resembling Those in Type II Lissencephaly

(2008) T. Inoue et al.   JOURNAL OF NEUROSCIENCE

Calcium signalling during neural induction in Xenopus laevis embryos

(2008) M. Moreau et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES