Bacterial serine proteases secreted by the autotransporter pathway: classification, specificity, and role in virulence

TIMgenes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

(2015) Gordon J. Freeman et al.   IMMUNOLOGICAL REVIEWS

Identification and Mechanism of Evolution of New Alleles Coding for the AIDA-I Autotransporter of Porcine Pathogenic Escherichia coli

(2012) Jean-Philippe Côté et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

VirK Is a Periplasmic Protein Required for Efficient Secretion of Plasmid-Encoded Toxin from Enteroaggregative Escherichia coli

(2012) Gabriela Tapia-Pastrana et al.   INFECTION AND IMMUNITY

From self sufficiency to dependence: mechanisms and factors important for autotransporter biogenesis

(2012) Denisse L. Leyton et al.   NATURE REVIEWS MICROBIOLOGY

Discovery of an archetypal protein transport system in bacterial outer membranes

(2012) Joel Selkrig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Type V secretion: mechanism(s) of autotransport through the bacterial outer membrane

(2012) J. C. Leo et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Bioinformatic Strategy for the Detection, Classification and Analysis of Bacterial Autotransporters

(2012) Nermin Celik et al.   PLoS One

Intimin and Invasin Export Their C-Terminus to the Bacterial Cell Surface Using an Inverse Mechanism Compared to Classical Autotransport

(2012) Philipp Oberhettinger et al.   PLoS One

Prevalence, Biogenesis, and Functionality of the Serine Protease Autotransporter EspP

(2012) André Weiss et al.   Toxins

Secreted autotransporter toxin (Sat) triggers autophagy in epithelial cells that relies on cell detachment

(2011) Vanessa Liévin-Le Moal et al.   CELLULAR MICROBIOLOGY

ATP-Independent Control of Autotransporter Virulence Protein Transport via the Folding Properties of the Secreted Protein

(2011) Jonathan P. Renn et al.   CHEMISTRY & BIOLOGY

Shigella are versatile mucosal pathogens that circumvent the host innate immune system

(2011) Hiroshi Ashida et al.   CURRENT OPINION IN IMMUNOLOGY

Crystal structure of theHaemophilus influenzaeHap adhesin reveals an intercellular oligomerization mechanism for bacterial aggregation

(2011) Guoyu Meng et al.   EMBO JOURNAL

The Essential  -Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis

(2011) A. E. Rossiter et al.   JOURNAL OF BACTERIOLOGY

Complete Genome Sequence of the Crohn's Disease-Associated Adherent-Invasive Escherichia coliStrain HM605

(2011) D. J. Clarke et al.   JOURNAL OF BACTERIOLOGY

Genome Sequence of a Porcine Extraintestinal Pathogenic Escherichia coli Strain

(2011) C. Tan et al.   JOURNAL OF BACTERIOLOGY

Genome of Multidrug-Resistant Uropathogenic Escherichia coli Strain NA114 from India

(2011) T. S. Avasthi et al.   JOURNAL OF BACTERIOLOGY

Adhesin Degradation Accelerates Delivery of Heat-labile Toxin by EnterotoxigenicEscherichia coli

(2011) Koushik Roy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Size and Conformation Limits to Secretion of Disulfide-bonded Loops in Autotransporter Proteins

(2011) Denisse L. Leyton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

(2011) Oscar Medina-Contreras et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomic Characterization of Enteroaggregative Escherichia coli From Children in Mali

(2011) N. Boisen et al.   JOURNAL OF INFECTIOUS DISEASES

Crystal Structure of the Passenger Domain of the Escherichia coli Autotransporter EspP

(2011) Shekeb Khan et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Basis for the Activation of a Catalytic Asparagine Residue in a Self-Cleaving Bacterial Autotransporter

(2011) Travis J. Barnard et al.   JOURNAL OF MOLECULAR BIOLOGY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Origins of theE. coliStrain Causing an Outbreak of Hemolytic–Uremic Syndrome in Germany

(2011) David A. Rasko et al.   NEW ENGLAND JOURNAL OF MEDICINE

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2011) N. D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Outbreak of Hemolytic-Uremic Syndrome Linked to Shiga Toxin-Producing Enteroaggregative Escherichia coli O104:H4

(2011)   PEDIATRIC RESEARCH

Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteins

(2011) F. Ruiz-Perez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential and spatially restricted interactions of assembly factors with an autotransporter   domain

(2011) R. Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salmonella bongori Provides Insights into the Evolution of the Salmonellae

(2011) Maria Fookes et al.   PLoS Pathogens

Role of domains within the autotransporter Hbp/Tsh

(2010) Kaoru Nishimura et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

CD34 mediates intestinal inflammation in Salmonella-infected mice

(2010) Guntram A. Grassl et al.   CELLULAR MICROBIOLOGY

Impaired innate immune response and enhanced pathology during Citrobacter rodentium infection in mice lacking functional P-selectin

(2010) Winnie W. S. Kum et al.   CELLULAR MICROBIOLOGY

Effects of the plasmid-encoded toxin of enteroaggregativeEscherichia colion focal adhesion complexes

(2010) Renato E. Cappello et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

EspP, a Serine Protease of Enterohemorrhagic Escherichia coli, Impairs Complement Activation by Cleaving Complement Factors C3/C3b and C5

(2010) D. Orth et al.   INFECTION AND IMMUNITY

Genome-Wide Transposon Mutagenesis Reveals a Role for pO157 Genes in Biofilm Development in Escherichia coli O157:H7 EDL933

(2010) S. Puttamreddy et al.   INFECTION AND IMMUNITY

Pic, an Autotransporter Protein Secreted by Different Pathogens in the Enterobacteriaceae Family, Is a Potent Mucus Secretagogue

(2010) F. Navarro-Garcia et al.   INFECTION AND IMMUNITY

YidC Is Involved in the Biogenesis of the Secreted Autotransporter Hemoglobin Protease

(2010) Wouter S. P. Jong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial Macroscopic Rope-like Fibers with Cytopathic and Adhesive Properties

(2010) Juan Xicohtencatl-Cortes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of a Full-Length Autotransporter

(2010) Bert van den Berg   JOURNAL OF MOLECULAR BIOLOGY

A Novel Intein-Like Autoproteolytic Mechanism in Autotransporter Proteins

(2010) Nami Tajima et al.   JOURNAL OF MOLECULAR BIOLOGY

Complete Genome Sequence and Comparative Metabolic Profiling of the Prototypical Enteroaggregative Escherichia coli Strain 042

(2010) Roy R. Chaudhuri et al.   PLoS One

Secretion of a bacterial virulence factor is driven by the folding of a C-terminal segment

(2010) Janine H. Peterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

(2010) D. G. Moriel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Serine Protease Autotransporters of Enterobacteriaceae (SPATEs): Biogenesis and Function

(2010) Nathalie Dautin   Toxins

Host-Toxin Interactions Involving EspC and Pet, Two Serine Protease Autotransporters of the Enterobacteriaceae

(2010) Fernando Navarro-Garcia et al.   Toxins

A host-specific factor is necessary for efficient folding of the autotransporter plasmid-encoded toxin☆

(2009) Kathleen N. Nemec et al.   BIOCHIMIE

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

PSGL-1 function in immunity and steady state homeostasis

(2009) Douglas A. Carlow et al.   IMMUNOLOGICAL REVIEWS

The Pic Protease of Enteroaggregative Escherichia coli Promotes Intestinal Colonization and Growth in the Presence of Mucin

(2009) S. M. Harrington et al.   INFECTION AND IMMUNITY

Roles of Periplasmic Chaperone Proteins in the Biogenesis of Serine Protease Autotransporters of Enterobacteriaceae

(2009) F. Ruiz-Perez et al.   JOURNAL OF BACTERIOLOGY

Complete Genome Sequence of the Wild-Type Commensal Escherichia coli Strain SE15, Belonging to Phylogenetic Group B2

(2009) H. Toh et al.   JOURNAL OF BACTERIOLOGY

Lack of Functional P-Selectin Ligand Exacerbates Salmonella Serovar Typhimurium Infection

(2009) Winnie W. S. Kum et al.   JOURNAL OF IMMUNOLOGY

Active-Site Gating Regulates Substrate Selectivity in a Chymotrypsin-Like Serine Protease

(2009) Troy A. Johnson et al.   JOURNAL OF MOLECULAR BIOLOGY

The Bam (Omp85) complex is involved in secretion of the autotransporter haemoglobin protease

(2009) A. Sauri et al.   MICROBIOLOGY-SGM

Vectorial transport and folding of an autotransporter virulence protein during outer membrane secretion

(2009) Mirco Junker et al.   MOLECULAR MICROBIOLOGY

MEROPS: the peptidase database

(2009) Neil D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Characterisation of Early Mucosal and Neuronal Lesions Following Shigella flexneri Infection in Human Colon

(2009) Emmanuel Coron et al.   PLoS One

The Immunogenic SigA Enterotoxin of Shigella flexneri 2a Binds to HEp-2 Cells and Induces Fodrin Redistribution in Intoxicated Epithelial Cells

(2009) Keith Al-Hasani et al.   PLoS One

Interaction of an autotransporter passenger domain with BamA during its translocation across the bacterial outer membrane

(2009) Raffaele Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secretion and subcellular localizations of bacterial proteins: a semantic awareness issue

(2009) Mickaël Desvaux et al.   TRENDS IN MICROBIOLOGY

Serine peptidases: Classification, structure and function

(2008) M. J. Page et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

EspC translocation into epithelial cells by enteropathogenicEscherichia colirequires a concerted participation of type V and III secretion systems

(2008) Jorge E. Vidal et al.   CELLULAR MICROBIOLOGY

RegA, an AraC-Like Protein, Is a Global Transcriptional Regulator That Controls Virulence Gene Expression in Citrobacter rodentium

(2008) E. Hart et al.   INFECTION AND IMMUNITY

Serine protease espP subtype α, but not β or γ, of Shiga toxin-producing Escherichia coli is associated with highly pathogenic serogroups

(2008) Abdul Basit Khan et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The serine protease motif of Pic mediates a dose-dependent mucolytic activity after binding to sugar constituents of the mucin substrate

(2008) Javier Gutiérrez-Jiménez et al.   MICROBIAL PATHOGENESIS

Phylogeny.fr: robust phylogenetic analysis for the non-specialist

(2008) A. Dereeper et al.   NUCLEIC ACIDS RESEARCH

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH

Common themes and variations in serine protease autotransporters

(2008) Yihfen T. Yen et al.   TRENDS IN MICROBIOLOGY