Insights into the mechanisms of sterol transport between organelles

Lipid-dependent protein sorting at the trans-Golgi network

(2012) Michal A. Surma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Phospholipid flippases: Building asymmetric membranes and transport vesicles

(2012) Tessy T. Sebastian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

A Sterol-Binding Protein Integrates Endosomal Lipid Metabolism with TOR Signaling and Nitrogen Sensing

(2012) Carl J. Mousley et al.   CELL

A Detour for Yeast Oxysterol Binding Proteins

(2012) Christopher T. Beh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 4-Kinase IIα Is Palmitoylated by Golgi-localized Palmitoyltransferases in Cholesterol-dependent Manner

(2012) Dongmei Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multisite phosphorylation of oxysterol-binding protein regulates sterol binding and activation of sphingomyelin synthesis

(2012) Asako Goto et al.   MOLECULAR BIOLOGY OF THE CELL

Sterol Transfer between Cyclodextrin and Membranes: Similar but Not Identical Mechanism to NPC2-Mediated Cholesterol Transfer

(2011) Leslie A. McCauliff et al.   BIOCHEMISTRY

Subcellular localization and regulation of StarD4 protein in macrophages and fibroblasts

(2011) Daniel Rodriguez-Agudo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

Lipid transfer and signaling at organelle contact sites: the tip of the iceberg

(2011) Alexandre Toulmay et al.   CURRENT OPINION IN CELL BIOLOGY

PI4P and Rab Inputs Collaborate in Myosin-V-Dependent Transport of Secretory Compartments in Yeast

(2011) Felipe H. Santiago-Tirado et al.   DEVELOPMENTAL CELL

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

(2011) Gregory D. Fairn et al.   JOURNAL OF CELL BIOLOGY

Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers

(2011) Maud de Saint-Jean et al.   JOURNAL OF CELL BIOLOGY

The mammalian START domain protein family in lipid transport in health and disease

(2011) Barbara J Clark   JOURNAL OF ENDOCRINOLOGY

Early steps in steroidogenesis: intracellular cholesterol trafficking

(2011) Walter L. Miller et al.   JOURNAL OF LIPID RESEARCH

STARD4 abundance regulates sterol transport and sensing

(2011) Bruno Mesmin et al.   MOLECULAR BIOLOGY OF THE CELL

Comparative Structural Analysis of Lipid Binding START Domains

(2011) Ann-Gerd Thorsell et al.   PLoS One

Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding

(2011) M. S. Deffieu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osh Proteins Regulate Membrane Sterol Organization but Are Not Required for Sterol Movement Between the ER and PM

(2011) Alexander G. Georgiev et al.   TRAFFIC

The Sterol-Binding Protein Kes1/Osh4p Is a Regulator of Polarized Exocytosis

(2011) Gabriel Alfaro et al.   TRAFFIC

Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network

(2011) Felipe H. Santiago-Tirado et al.   TRENDS IN CELL BIOLOGY

The Distribution and Function of Phosphatidylserine in Cellular Membranes

(2010) Peter A. Leventis et al.   Annual Review of Biophysics

The Diverse Functions of Oxysterol-Binding Proteins

(2010) Sumana Raychaudhuri et al.   Annual Review of Cell and Developmental Biology

Lipid Trafficking sans Vesicles: Where, Why, How?

(2010) William A. Prinz   CELL

Identification of Surface Residues on Niemann-Pick C2 Essential for Hydrophobic Handoff of Cholesterol to NPC1 in Lysosomes

(2010) Michael L. Wang et al.   Cell Metabolism

The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

(2010) Ira Tabas   CIRCULATION RESEARCH

Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotype

(2010) Faye Borthwick et al.   CLINICAL SCIENCE

Cholesterol, the central lipid of mammalian cells

(2010) Frederick R Maxfield et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphatidylinositol 4-Phosphate Controls Both Membrane Recruitment and a Regulatory Switch of the Rab GEF Sec2p

(2010) Emi Mizuno-Yamasaki et al.   DEVELOPMENTAL CELL

Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function

(2010) Andrew Manford et al.   EMBO JOURNAL

Lipid Binding Requirements for Oxysterol-binding Protein Kes1 Inhibition of Autophagy and Endosome-trans-Golgi Trafficking Pathways

(2010) Marissa A. LeBlanc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches

(2010) Anton I. Rosenbaum et al.   JOURNAL OF NEUROCHEMISTRY

Oxysterol Binding Protein-dependent Activation of Sphingomyelin Synthesis in the Golgi Apparatus Requires Phosphatidylinositol 4-Kinase IIα

(2010) Sangeeta Banerji et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of Oxysterol-binding Protein Golgi Localization through Protein Kinase D–mediated Phosphorylation

(2010) Sokha Nhek et al.   MOLECULAR BIOLOGY OF THE CELL

Non-vesicular lipid transport by lipid-transfer proteins and beyond

(2010) Sima Lev   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of ORPs in Sterol Transport from Plasma Membrane to ER and Lipid Droplets in Mammalian Cells

(2010) Maurice Jansen et al.   TRAFFIC

Intracellular sterol dynamics

(2009) Bruno Mesmin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

CERT-mediated trafficking of ceramide

(2009) Kentaro Hanada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Niemann–Pick C2 (NPC2) and intracellular cholesterol trafficking

(2009) Judith Storch et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

(2009) Hyock Joo Kwon et al.   CELL

Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network

(2009) Robin W. Klemm et al.   JOURNAL OF CELL BIOLOGY

Lipid-regulated sterol transfer between closely apposed membranes by oxysterol-binding protein homologues

(2009) Timothy A. Schulz et al.   JOURNAL OF CELL BIOLOGY

Targeted disruption of steroidogenic acute regulatory protein D4 leads to modest weight reduction and minor alterations in lipid metabolism

(2009) Joshua J. Riegelhaupt et al.   JOURNAL OF LIPID RESEARCH

MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein

(2009) Mark Charman et al.   JOURNAL OF LIPID RESEARCH

Yeast oxysterol-binding proteins: sterol transporters or regulators of cell polarization?

(2009) Christopher T. Beh et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Control of Protein and Sterol Trafficking by Antagonistic Activities of a Type IV P-type ATPase and Oxysterol Binding Protein Homologue

(2009) Baby-Periyanayaki Muthusamy et al.   MOLECULAR BIOLOGY OF THE CELL

Oxysterol Binding Protein–related Protein 9 (ORP9) Is a Cholesterol Transfer Protein That Regulates Golgi Structure and Function

(2009) Mike Ngo et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of a Golgi flippase by phosphoinositides and an ArfGEF

(2009) Paramasivam Natarajan et al.   NATURE CELL BIOLOGY

Regulation of Sterol Transport between Membranes and NPC2†

(2008) Zhi Xu et al.   BIOCHEMISTRY

Switch-like Control of SREBP-2 Transport Triggered by Small Changes in ER Cholesterol: A Delicate Balance

(2008) Arun Radhakrishnan et al.   Cell Metabolism

Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation

(2008) Daniel Rodriguez-Agudo et al.   JOURNAL OF LIPID RESEARCH

Coordinated Lipid Transfer between the Endoplasmic Reticulum and the Golgi Complex Requires the VAP Proteins and Is Essential for Golgi-mediated Transport

(2008) Diego Peretti et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

(2008) R. E. Infante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide

(2008) N. Kudo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sterol regulators of cholesterol homeostasis and beyond: The oxysterol hypothesis revisited and revised

(2008) S GILL et al.   PROGRESS IN LIPID RESEARCH

Cholesterol homeostasis and the escape tendency (activity) of plasma membrane cholesterol

(2008) Yvonne Lange et al.   PROGRESS IN LIPID RESEARCH