Developmental mechanisms directing early anterior forebrain specification in vertebrates

Modulation of WNT signaling activity is key to the formation of the embryonic head

(2012) Nicolas Fossat et al.   CELL CYCLE

The hypoblast (visceral endoderm): an evo-devo perspective

(2012) C. D. Stern et al.   DEVELOPMENT

Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling

(2012) D. Carlin et al.   DEVELOPMENT

Function of Wnt/ -catenin in counteracting Tcf3 repression through the Tcf3- -catenin interaction

(2012) C.-I. Wu et al.   DEVELOPMENT

BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis

(2012) Holger Bielen et al.   DEVELOPMENTAL CELL

Directing Differentiation of Human Embryonic Stem Cells Toward Anterior Neural Ectoderm Using Small Molecules

(2012) Beata Surmacz et al.   STEM CELLS

Multi-Cellular Rosettes in the Mouse Visceral Endoderm Facilitate the Ordered Migration of Anterior Visceral Endoderm Cells

(2012) Georgios Trichas et al.   PLOS BIOLOGY

Crosstalk between Nodal/Activin and MAPK p38 Signaling Is Essential for Anterior-Posterior Axis Specification

(2011) Melanie Clements et al.   CURRENT BIOLOGY

Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo

(2011) N. Fossat et al.   DEVELOPMENT

HESX1- and TCF3-mediated repression of Wnt/ -catenin targets is required for normal development of the anterior forebrain

(2011) C. L. Andoniadou et al.   DEVELOPMENT

Sox2-mediated differential activation of Six3.2 contributes to forebrain patterning

(2011) L. Beccari et al.   DEVELOPMENT

β-Catenin-Dependent FGF Signaling Sustains Cell Survival in the Anterior Embryonic Head by Countering Smad4

(2011) Hunki Paek et al.   DEVELOPMENTAL CELL

FGF signalling inhibits neural induction in human embryonic stem cells

(2011) Boris Greber et al.   EMBO JOURNAL

Tracking adult stem cells

(2011) Hugo J Snippert et al.   EMBO REPORTS

Origin and role of distal visceral endoderm, a group of cells that determines anterior–posterior polarity of the mouse embryo

(2011) Katsuyoshi Takaoka et al.   NATURE CELL BIOLOGY

Nodal Dependent Differential Localisation of Dishevelled-2 Demarcates Regions of Differing Cell Behaviour in the Visceral Endoderm

(2011) Georgios Trichas et al.   PLOS BIOLOGY

Sonic hedgehog functions through dynamic changes in temporal competence in the developing forebrain

(2010) Vitor H Sousa et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The origin and identity of embryonic stem cells

(2010) J. Nichols et al.   DEVELOPMENT

The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice

(2010) M. Manuel et al.   DEVELOPMENT

The role of FGF/Erk signaling in pluripotent cells

(2010) F. Lanner et al.   DEVELOPMENT

The role of FGF-signaling in early neural specification of human embryonic stem cells

(2010) Malkiel A. Cohen et al.   DEVELOPMENTAL BIOLOGY

Bmpr1a is required for proper migration of the AVE through regulation of Dkk1 expression in the pre-streak mouse embryo

(2010) Shigeto Miura et al.   DEVELOPMENTAL BIOLOGY

BMP antagonism protects Nodal signaling in the gastrula to promote the tissue interactions underlying mammalian forebrain and craniofacial patterning

(2010) Yu-Ping Yang et al.   HUMAN MOLECULAR GENETICS

Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells

(2010) Asuka Morizane et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neural Induction Intermediates Exhibit Distinct Roles of Fgf Signaling

(2010) Jared Sterneckert et al.   STEM CELLS

Retinoic Acid Synthesis Promotes Development of Neural Progenitors from Mouse Embryonic Stem Cells by Suppressing Endogenous, Wnt-Dependent Nodal Signaling

(2010) Nina Engberg et al.   STEM CELLS

FGF signaling is strictly required to maintain early telencephalic precursor cell survival

(2009) H. Paek et al.   DEVELOPMENT

The Xenopus Irx genes are essential for neural patterning and define the border between prethalamus and thalamus through mutual antagonism with the anterior repressors Fezf and Arx

(2009) Elisa Rodríguez-Seguel et al.   DEVELOPMENTAL BIOLOGY

Incipient forebrain boundaries traced by differential gene expression and fate mapping in the chick neural plate

(2009) Luisa Sánchez-Arrones et al.   DEVELOPMENTAL BIOLOGY

BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus

(2009) Andrea E. Wills et al.   DEVELOPMENTAL BIOLOGY

SOX–partner code for cell specification: Regulatory target selection and underlying molecular mechanisms

(2009) Hisato Kondoh et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Regulation of pre-otic brain development by the cephalic neural crest

(2009) S. E. Creuzet   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genes and signaling events that establish regional patterning of the mammalian forebrain

(2009) Renée V. Hoch et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of Neural Specification from Human Embryonic Stem Cells by BMP and FGF

(2009) Timothy M. LaVaute et al.   STEM CELLS

Integrating positional information at the level of Smad1/5/8

(2008) Edward Eivers et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Wnt-regulated temporal control of BMP exposure directs the choice between neural plate border and epidermal fate

(2008) C. Patthey et al.   DEVELOPMENT

Dkk1 and Wnt3 interact to control head morphogenesis in the mouse

(2008) S. L. Lewis et al.   DEVELOPMENT

Genetic interaction between the homeobox transcription factors HESX1 and SIX3 is required for normal pituitary development

(2008) Carles Gaston-Massuet et al.   DEVELOPMENTAL BIOLOGY

The Endoderm of the Mouse Embryo Arises by Dynamic Widespread Intercalation of Embryonic and Extraembryonic Lineages

(2008) Gloria S. Kwon et al.   DEVELOPMENTAL CELL

Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon

(2007) A. Lavado et al.   DEVELOPMENT