Going vertical: functional role and working principles of the protein Inscuteable in asymmetric cell divisions

An Asymmetrically Localized Staufen2-Dependent RNA Complex Regulates Maintenance of Mammalian Neural Stem Cells

(2012) John P. Vessey et al.   Cell Stem Cell

Cortical dynein is critical for proper spindle positioning in human cells

(2012) Sachin Kotak et al.   JOURNAL OF CELL BIOLOGY

Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

(2012) Tomomi Kiyomitsu et al.   NATURE CELL BIOLOGY

Inscuteable Regulates the Pins-Mud Spindle Orientation Pathway

(2012) Jonathon F. Mauser et al.   PLoS One

ABL1 regulates spindle orientation in adherent cells and mammalian skin

(2012) Shigeru Matsumura et al.   Nature Communications

On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN

(2012) M. Mapelli et al.   Open Biology

LGN-dependent orientation of cell divisions in the dermomyotome controls lineage segregation into muscle and dermis

(2011) R. Ben-Yair et al.   DEVELOPMENT

Cell polarity and spindle orientation in the distal epithelium of embryonic lung

(2011) Ahmed H. El-Hashash et al.   DEVELOPMENTAL DYNAMICS

A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells

(2011) Elise Peyre et al.   JOURNAL OF CELL BIOLOGY

LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways

(2011) Jinwei Zhu et al.   MOLECULAR CELL

Asymmetric cell divisions promote Notch-dependent epidermal differentiation

(2011) Scott E. Williams et al.   NATURE

Mouse Inscuteable Induces Apical-Basal Spindle Orientation to Facilitate Intermediate Progenitor Generation in the Developing Neocortex

(2011) Maria Pia Postiglione et al.   NEURON

Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions

(2011) S. Culurgioni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for interaction between the conserved cell polarity proteins Inscuteable and Leu-Gly-Asn repeat-enriched protein (LGN)

(2011) S. Yuzawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Par3 Controls Epithelial Spindle Orientation by aPKC-Mediated Phosphorylation of Apical Pins

(2010) Yi Hao et al.   CURRENT BIOLOGY

Robust control of mitotic spindle orientation in the developing epidermis

(2010) Nicholas D. Poulson et al.   JOURNAL OF CELL BIOLOGY

Identification of an Aurora-A/PinsLINKER/ Dlg Spindle Orientation Pathway using Induced Cell Polarity in S2 Cells

(2009) Christopher A. Johnston et al.   CELL

On the roles of Notch, Delta, kuzbanian, and inscuteable during the development of Drosophila embryonic neuroblast lineages

(2009) Gerald Udolph et al.   DEVELOPMENTAL BIOLOGY

Adherens junction domains are split by asymmetric division of embryonic neural stem cells

(2009) Véronique Marthiens et al.   EMBO REPORTS

Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer

(2009) R. A. Neumuller et al.   GENES & DEVELOPMENT