Neutrophil uptake of nitrogen-bisphosphonates leads to the suppression of human peripheral blood γδ T cells

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human    T-cell subset

(2012) C. Harly et al.   BLOOD

Defining the nature of human γδ T cells: a biographical sketch of the highly empathetic

(2012) Shirin Kalyan et al.   Cellular & Molecular Immunology

Monocytes and γδ T cells control the acute-phase response to intravenous zoledronate: Insights from a phase IV safety trial

(2012) Joanne L Welton et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Can peripheral bloodγδT cells predict osteonecrosis of the jaw? An immunological perspective on the adverse drug effects of aminobisphosphonate therapy

(2012) Shirin Kalyan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bisphosphonates: The first 40years

(2011) R. Graham G. Russell   BONE

Zoledronate and pamidronate depress neutrophil functions and survival in mice

(2011) JWP Kuiper et al.   BRITISH JOURNAL OF PHARMACOLOGY

Phase I/II study of adoptive transfer of γδ T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma

(2011) Hirohito Kobayashi et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Pilot trial of interleukin-2 and zoledronic acid to augment γδ T cells as treatment for patients with refractory renal cell carcinoma

(2011) Joshua M. Lang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Neutrophil Degranulation and Immunosuppression in Patients with GBM: Restoration of Cellular Immune Function by Targeting Arginase I

(2011) T. R. Sippel et al.   CLINICAL CANCER RESEARCH

Aminobisphosphonates and Toll-Like Receptor Ligands: Recruiting Vγ9Vδ2 T Cells for the Treatment of Hematologic Malignancy

(2011) S. Kalyan et al.   CURRENT MEDICINAL CHEMISTRY

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation

(2011) R. Rotondo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Neutrophil Clearance of Bacterial Pathogens Triggers Anti-Microbial γδ T Cell Responses in Early Infection

(2011) Martin S. Davey et al.   PLoS Pathogens

Aminobisphosphonate-pretreated dendritic cells trigger successful Vγ9Vδ2 T cell amplification for immunotherapy in advanced cancer patients

(2010) Florian Cabillic et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Neutrophil Elastase, Proteinase 3, and Cathepsin G as Therapeutic Targets in Human Diseases

(2010) B. Korkmaz et al.   PHARMACOLOGICAL REVIEWS

Zoledronic acid and interleukin-2 treatment improves immunocompetence in HIV-infected persons by activating Vγ9Vδ2 T cells

(2009) Fabrizio Poccia et al.   AIDS

Antiinflammatory Effects of Hydrogen Peroxide in Neutrophil Activation and Acute Lung Injury

(2009) Jaroslaw W. Zmijewski et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Fluorescently Labeled Risedronate and Related Analogues: “Magic Linker” Synthesis

(2008) Boris A. Kashemirov et al.   BIOCONJUGATE CHEMISTRY

Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

(2008) Anke J. Roelofs et al.   BRITISH JOURNAL OF HAEMATOLOGY

Zoledronate facilitates large-scale ex vivo expansion of functional γδ T cells from cancer patients for use in adoptive immunotherapy*

(2008) M. Kondo et al.   CYTOTHERAPY

Insight into bisphosphonate-associated osteomyelitis of the jaw: pathophysiology, mechanisms and clinical management

(2008) Sunil J Wimalawansa   Expert Opinion On Drug Safety

Neutrophil serine proteases fine-tune the inflammatory response

(2007) C PHAM   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY