The Akt-associated microRNAs

Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells

(2012) Ming Shi et al.   JOURNAL OF PATHOLOGY

Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells

(2012) Mohit Sachdeva et al.   NUCLEIC ACIDS RESEARCH

Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop

(2012) J Zhang et al.   ONCOGENE

p53 and c-myc: How does the cell balance “yin” and “yang”?

(2011) Mohit Sachdeva et al.   CELL CYCLE

Overexpression of miR-200c Induces Chemoresistance in Esophageal Cancers Mediated Through Activation of the Akt Signaling Pathway

(2011) R. Hamano et al.   CLINICAL CANCER RESEARCH

miR-605joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress

(2011) Jiening Xiao et al.   EMBO JOURNAL

FGF-2 Regulates Cell Proliferation, Migration, and Angiogenesis through an NDY1/KDM2B-miR-101-EZH2 Pathway

(2011) Filippos Kottakis et al.   MOLECULAR CELL

Cellular Stress Induced Alterations in MicroRNA let-7a and let-7b Expression Are Dependent on p53

(2011) Anthony D. Saleh et al.   PLoS One

Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis

(2011) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-190-Mediated Downregulation of PHLPP Contributes to Arsenic-Induced Akt Activation and Carcinogenesis

(2011) Kevin Beezhold et al.   TOXICOLOGICAL SCIENCES

FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis

(2010) Boyi Gan et al.   CANCER CELL

MicroRNAs reduce tumor growth and contribute to enhance cytotoxicity induced by gefitinib in non-small cell lung cancer

(2010) Miao Zhong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

MiR-222 Overexpression Confers Cell Migratory Advantages in Hepatocellular Carcinoma through Enhancing AKT Signaling

(2010) Q. W-L. Wong et al.   CLINICAL CANCER RESEARCH

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

(2010) O. A. Kent et al.   GENES & DEVELOPMENT

Vitamin D3Up-regulated Protein 1(VDUP1) Is Regulated by FOXO3A and miR-17-5p at the Transcriptional and Post-transcriptional Levels, Respectively, in Senescent Fibroblasts

(2010) De Xiang Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Foxo3a Regulates Apoptosis by Negatively Targeting miR-21

(2010) Kun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-101-mediated Akt activation and estrogen-independent growth

(2010) M Sachdeva et al.   ONCOGENE

MicroRNA-145 Targets YES and STAT1 in Colon Cancer Cells

(2010) Lea H. Gregersen et al.   PLoS One

miR-22 Forms a Regulatory Loop in PTEN/AKT Pathway and Modulates Signaling Kinetics

(2010) Nadav Bar et al.   PLoS One

Targeting DNA-PKcs and ATM with miR-101 Sensitizes Tumors to Radiation

(2010) Dan Yan et al.   PLoS One

Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a

(2010) Huanxin Lin et al.   PLoS One

Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486

(2010) E. M. Small et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the miR-106b 25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation

(2010) L. Poliseno et al.   Science Signaling

Switching Akt: from survival signaling to deadly response

(2009) Marek Los et al.   BIOESSAYS

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

The Putative Tumor Suppressor microRNA-101 Modulates the Cancer Epigenome by Repressing the Polycomb Group Protein EZH2

(2009) J. M. Friedman et al.   CANCER RESEARCH

MicroRNA-101, Down-regulated in Hepatocellular Carcinoma, Promotes Apoptosis and Suppresses Tumorigenicity

(2009) H. Su et al.   CANCER RESEARCH

miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-α in human breast cancer cells

(2009) R Spizzo et al.   CELL DEATH AND DIFFERENTIATION

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

(2009) Hong-li Yan et al.   EMBO JOURNAL

Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation

(2009) William C.S. Cho et al.   EUROPEAN JOURNAL OF CANCER

Mechanism of growth inhibition by MicroRNA 145: The role of the IGF-I receptor signaling pathway

(2009) Gaspare La Rocca et al.   JOURNAL OF CELLULAR PHYSIOLOGY

miR-22 Inhibits Estrogen Signaling by Directly Targeting the Estrogen Receptor   mRNA

(2009) D. P. Pandey et al.   MOLECULAR AND CELLULAR BIOLOGY

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors

(2009) M S Ostenfeld et al.   ONCOGENE

Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor

(2009) Miguel F. Segura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-206 Expression Is Down-regulated in Estrogen Receptor  -Positive Human Breast Cancer

(2008) N. Kondo et al.   CANCER RESEARCH

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

MicroRNA-21 targets tumor suppressor genes in invasion and metastasis

(2008) Shuomin Zhu et al.   CELL RESEARCH

Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke

(2008) Alberto Izzotti et al.   FASEB JOURNAL

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

MicroRNA-221/222 Negatively Regulates Estrogen Receptorα and Is Associated with Tamoxifen Resistance in Breast Cancer

(2008) Jian-Jun Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28

(2008) Elena Piskounova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1

(2008) Tyler E. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

REST maintains self-renewal and pluripotency of embryonic stem cells

(2008) Sanjay K. Singh et al.   NATURE

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE

Gene Regulation by Transcription Factors and MicroRNAs

(2008) O. Hobert   SCIENCE

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE