The exportomer: the peroxisomal receptor export machinery

Pex14 is the sole component of the peroxisomal translocon that is required for pexophagy

(2014) Tim van Zutphen et al.   Autophagy

Mitochondrial quality control by the ubiquitin–proteasome system: Figure 1

(2012) Eric B. Taylor et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Biochemically Distinct Vesicles from the Endoplasmic Reticulum Fuse to Form Peroxisomes

(2012) Adabella van der Zand et al.   CELL

The RING-type ubiquitin ligases Pex2p, Pex10p and Pex12p form a heteromeric complex that displays enhanced activity in an ubiquitin conjugating enzyme-selective manner

(2012) Fouzi El Magraoui et al.   FEBS Journal

The peroxisome: an update on mysteries

(2012) Markus Islinger et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Identification of Ubiquitin-specific Protease 9X (USP9X) as a Deubiquitinase Acting on Ubiquitin-Peroxin 5 (PEX5) Thioester Conjugate

(2012) Cláudia P. Grou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Core Components and Transient Interactors of the Peroxisomal Importomer by Dual-Track Stable Isotope Labeling with Amino Acids in Cell Culture Analysis

(2012) Silke Oeljeklaus et al.   JOURNAL OF PROTEOME RESEARCH

Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system

(2012) Hemmo Meyer et al.   NATURE CELL BIOLOGY

Phylloquinone (vitamin K1) biosynthesis in plants: two peroxisomal thioesterases of lactobacillales origin hydrolyze 1,4-dihydroxy-2-naphthoyl-coa

(2012) Joshua R. Widhalm et al.   PLANT JOURNAL

Distinct conformations of the protein complex p97-Ufd1-Npl4 revealed by electron cryomicroscopy

(2012) C. Bebeacua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Requirements for Peroxisomal Targeting of Alanine-Glyoxylate Aminotransferase as an Essential Determinant in Primary Hyperoxaluria Type 1

(2012) Krisztián Fodor et al.   PLOS BIOLOGY

Peroxisomal alterations in Alzheimer’s disease

(2011) Jianqiu Kou et al.   ACTA NEUROPATHOLOGICA

Cdc48/p97, a key actor in the interplay between autophagy and ubiquitin/proteasome catabolic pathways

(2011) Catherine Dargemont et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Insights into ubiquitin-conjugating enzyme/ co-activator interactions from the structure of the Pex4p:Pex22p complex

(2011) Chris Williams et al.   EMBO JOURNAL

Peroxisomes: Membrane events accompanying peroxisome proliferation

(2011) Łukasz Opaliński et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Two Proteases, Trypsin Domain-containing 1 (Tysnd1) and Peroxisomal Lon Protease (PsLon), Cooperatively Regulate Fatty Acid β-Oxidation in Peroxisomal Matrix

(2011) Kanji Okumoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cysteine-dependent Ubiquitination of Pex18p Is Linked to Cargo Translocation across the Peroxisomal Membrane

(2011) Astrid Hensel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PEX5 Protein Binds Monomeric Catalase Blocking Its Tetramerization and Releases It upon Binding the N-terminal Domain of PEX14

(2011) Marta O. Freitas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubp15p, a Ubiquitin Hydrolase Associated with the Peroxisomal Export Machinery

(2011) Mykhaylo O. Debelyy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PEX14 is required for microtubule-based peroxisome motility in human cells

(2011) P. Bharti et al.   JOURNAL OF CELL SCIENCE

Pheromone Gland Development and Pheromone Production in Lutzomyia longipalpis (Diptera: Psychodidae: Phlebotominae)

(2011) Carolina N. Spiegel et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk

(2011) Oksana Ivashchenko et al.   MOLECULAR BIOLOGY OF THE CELL

Functional diversification of the RING finger and other binuclear treble clef domains in prokaryotes and the early evolution of the ubiquitin system

(2011) A. Maxwell Burroughs et al.   Molecular BioSystems

The importomer peroxins are differentially required for peroxisome assembly and meiotic development in Podospora anserina: insights into a new peroxisome import pathway

(2011) Leonardo Peraza-Reyes et al.   MOLECULAR MICROBIOLOGY

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

(2011) Dawn M. Wenzel et al.   NATURE

Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity

(2011) Sabrina Diano et al.   NATURE MEDICINE

Identification of Novel Plant Peroxisomal Targeting Signals by a Combination of Machine Learning Methods and in Vivo Subcellular Targeting Analyses

(2011) Thomas Lingner et al.   PLANT CELL

ArabidopsisABERRANT PEROXISOME MORPHOLOGY9 Is a Peroxin That Recruits the PEX1-PEX6 Complex to Peroxisomes

(2011) Shino Goto et al.   PLANT CELL

A Single Peroxisomal Targeting Signal Mediates Matrix Protein Import in Diatoms

(2011) Nicola H. Gonzalez et al.   PLoS One

Ubiquitination of Substrates by Esterification

(2011) Xiaoli Wang et al.   TRAFFIC

Recruiting Mechanism of the AAA Peroxins, Pex1p and Pex6p, to Pex26p on the Peroxisomal Membrane

(2011) Chika Nashiro et al.   TRAFFIC

Cysteine Ubiquitination of PTS1 Receptor Pex5p Regulates Pex5p Recycling

(2011) Kanji Okumoto et al.   TRAFFIC

AWP1/ZFAND6 Functions in Pex5 Export by Interacting with Cys-Monoubiquitinated Pex5 and Pex6 AAA ATPase

(2011) Non Miyata et al.   TRAFFIC

Peroxisomes Are Required for Efficient Penicillin Biosynthesis in Penicillium chrysogenum

(2010) W. H. Meijer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

Identification of PEX33, a novel component of the peroxisomal docking complex in the filamentous fungus Neurospora crassa

(2010) David Managadze et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Penicillium chrysogenum Pex14/17p - a novel component of the peroxisomal membrane that is important for penicillin production

(2010) Łukasz Opaliński et al.   FEBS Journal

Genetic classification and mutational spectrum of more than 600 patients with a Zellweger syndrome spectrum disorder

(2010) Merel S. Ebberink et al.   HUMAN MUTATION

Contribution of the PeroxisomalacoxGene to the Dynamic Balance of Daumone Production inCaenorhabditis elegans

(2010) Hyoe-Jin Joo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serine Residues in the Cytosolic Tail of the T-cell Antigen Receptor α-Chain Mediate Ubiquitination and Endoplasmic Reticulum-associated Degradation of the Unassembled Protein

(2010) Shuhei Ishikura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Proteome-Wide Perspective on Peroxisome Targeting Signal 1(PTS1)-Pex5p Affinities

(2010) Debdip Ghosh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interdependence of the Peroxisome-targeting Receptors in Arabidopsis thaliana: PEX7 Facilitates PEX5 Accumulation and Import of PTS1 Cargo into Peroxisomes

(2010) Naxhiely Martínez Ramón et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitylation of an ERAD Substrate Occurs on Multiple Types of Amino Acids

(2010) Yuichiro Shimizu et al.   MOLECULAR CELL

Molecular mechanisms of organelle inheritance: lessons from peroxisomes in yeast

(2010) Andrei Fagarasanu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Peroxisomal protein import and ERAD: variations on a common theme

(2010) Wolfgang Schliebs et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Different functions of the C3HC4 zinc RING finger peroxins PEX10, PEX2, and PEX12 in peroxisome formation and matrix protein import

(2010) J. Prestele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reducing PEX13 Expression Ameliorates Physiological Defects of Late-Acting Peroxin Mutants

(2010) Sarah E. Ratzel et al.   TRAFFIC

Peroxisome Metabolism and Cellular Aging

(2010) Vladimir I. Titorenko et al.   TRAFFIC

RING Domain E3 Ubiquitin Ligases

(2009) Raymond J. Deshaies et al.   Annual Review of Biochemistry

In vitro import of peroxisome-targeting signal type 2 (PTS2) receptor Pex7p into peroxisomes

(2009) Non Miyata et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Identification of polyubiquitin binding proteins involved in NF-κB signaling using protein arrays

(2009) Beau J. Fenner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Reactive oxygen species and peroxisomes: Struggling for balance

(2009) Nina A. Bonekamp et al.   BIOFACTORS

Protein transport across the peroxisomal membrane

(2009) Wolfgang Girzalsky et al.   BIOLOGICAL CHEMISTRY

FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination

(2009) Sirio Dupont et al.   CELL

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19

(2009) Christian Neufeld et al.   EMBO JOURNAL

Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase

(2009) Koji Okamoto et al.   FEBS LETTERS

Solution Structure of Human Pex5·Pex14·PTS1 Protein Complexes Obtained by Small Angle X-ray Scattering

(2009) Kumiko Shiozawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Properties of the Ubiquitin-Pex5p Thiol Ester Conjugate

(2009) Cláudia P. Grou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping the Cargo Protein Membrane Translocation Step into the PEX5 Cycling Pathway

(2009) Inês S. Alencastre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation

(2009) Z. Kostova et al.   JOURNAL OF CELL SCIENCE

Pex2 and Pex12 Function as Protein-Ubiquitin Ligases in Peroxisomal Protein Import

(2009) H. W. Platta et al.   MOLECULAR AND CELLULAR BIOLOGY

The Peroxisomal Matrix Import of Pex8p Requires Only PTS Receptors and Pex14p

(2009) Changle Ma et al.   MOLECULAR BIOLOGY OF THE CELL

The ubiquitylation machinery of the endoplasmic reticulum

(2009) Christian Hirsch et al.   NATURE

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

(2009) Martin Schwickart et al.   NATURE

Viral avoidance and exploitation of the ubiquitin system

(2009) Felix Randow et al.   NATURE CELL BIOLOGY

The E3 Ubiquitin-Ligase Bmi1/Ring1A Controls the Proteasomal Degradation of Top2α Cleavage Complex – A Potentially New Drug Target

(2009) Iris Alchanati et al.   PLoS One

Crystal structure of the conserved N-terminal domain of the peroxisomal matrix protein import receptor, Pex14p

(2009) J.-R. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peroxisome-associated matrix protein degradation in Arabidopsis

(2009) M. J. Lingard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localization of mRNAs coding for peroxisomal proteins in the yeast, Saccharomyces cerevisiae

(2009) G. Zipor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence analysis of the AAA protein family

(2009) Andreas Beyer   PROTEIN SCIENCE

Divide et Impera: The Dictum of Peroxisomes

(2009) Shirisha Nagotu et al.   TRAFFIC

Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p

(2008) Chris Williams et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The AAA peroxins Pex1p and Pex6p function as dislocases for the ubiquitinated peroxisomal import receptor Pex5p

(2008) Harald W. Platta et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

UBX domain proteins: major regulators of the AAA ATPase Cdc48/p97

(2008) C. Schuberth et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The peroxisomal protein import machinery – a case report of transient ubiquitination with a new flavor

(2008) C. P. Grou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Loss of peroxisome function triggers necrosis

(2008) Helmut Jungwirth et al.   FEBS LETTERS

Members of the E2D (UbcH5) Family Mediate the Ubiquitination of the Conserved Cysteine of Pex5p, the Peroxisomal Import Receptor

(2008) Cláudia P. Grou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cue1p Is an Activator of Ubc7p E2 Activityin Vitroandin Vivo

(2008) Omar A. Bazirgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Jasmonates meet fatty acids: functional analysis of a new acyl-coenzyme A synthetase family from Arabidopsis thaliana

(2008) Lucie Kienow et al.   JOURNAL OF EXPERIMENTAL BOTANY

Organelle dynamics and dysfunction: A closer link between peroxisomes and mitochondria

(2008) F. Camões et al.   JOURNAL OF INHERITED METABOLIC DISEASE

The Specificities of Kaposi's Sarcoma-Associated Herpesvirus-Encoded E3 Ubiquitin Ligases Are Determined by the Positions of Lysine or Cysteine Residues within the Intracytoplasmic Domains of Their Targets

(2008) K. Cadwell et al.   JOURNAL OF VIROLOGY

The DEG15 Serine Protease Cleaves Peroxisomal Targeting Signal 2-Containing Proteins in Arabidopsis

(2008) H. Schuhmann et al.   PLANT PHYSIOLOGY

Improved Structures of Full-Length p97, an AAA ATPase: Implications for Mechanisms of Nucleotide-Dependent Conformational Change

(2008) Jason M. Davies et al.   STRUCTURE

The Peroxisome RING-Finger Complex is Required for Meiocyte Formation in the FungusPodospora anserina

(2008) Leonardo Peraza-Reyes et al.   TRAFFIC

The Ubiquitin E3 Ligase MARCH7 is Differentially Regulated by the Deubiquitylating Enzymes USP7 and USP9X

(2008) James A. Nathan et al.   TRAFFIC